Toyota City, Japan, Nov 10, 2025 - (JCN Newswire via SeaPRwire.com) - Toyota Motor Corporation (Toyota) announced that it will globally deploy diverse powertrains, including battery electric vehicles (BEVs) and fuel cell electric vehicles (FCEVs), based on its multi-pathway approach to achieve a carbon-neutral society. On November 10, Toyota held the world premiere of the new Hilux, which includes a new BEV model, at a new vehicle announcement event held by Toyota Motor Asia (TMA)*1 in Bangkok, Thailand. In Asia, Toyota plans to launch sequentially from 2026 onward. For Japan-bound models, where a diesel version is planned, the launch is scheduled for mid-2026*2.Toward Carbon NeutralityToyota is committed to product- and region-centered management with the aim of making ever-better cars. In developing powertrain systems to achieve carbon neutrality, various types of mobility are being introduced as part of Toyota's multi-pathway approach. This approach offers electrified vehicle options tailored to the energy circumstances and varied customer needs in each country and region worldwide.With the new Hilux, Toyota will further accelerate the multi-pathway approach by developing an FCEV model in addition to the diesel and BEV models announced today. The FCEV model is scheduled to be introduced in Europe and Oceania starting in 2028.*1 Toyota's operating company in Asia*2 A special website will be launched today and information will be updated regularly. The special website can be accessed here.The Hilux (BEV model) announced in ThailandThe Hilux (BEV model displayed at the event, Prototype)This model is equipped with a lithium-ion battery with a total electric power of 59.2 kWh*3. Cruising range of 300 km or more*4 is achieved by increasing eAxle efficiency.The battery pack is installed under the floor, making full use of the frame width.High-output eAxles are used in the front and rear, providing maximum system output*5 of 144 kW, and an advanced control system achieves excellent off-road performance.Main Hilux (BEV model, Prototype) specifications for ThailandDriveline4WDLength (mm)5,320Width (mm)1,855Height (mm)1,800Wheelbase (mm)3,085Battery capacity (total electric power) (kWh)*359.2Cruising range (km)*4300 or moreMaximum system output (kW)*5144 *3 Measured in accordance with IEC standard 62660-1*4 NEDC mode value; development target value*5 Output that can be achieved by the system (value calculated by Toyota)Moving forward, Toyota will continue to address customer needs in each region and contribute to carbon neutrality by developing various options while striving to make ever-better cars.The speech by Chief Branding Officer Simon Humphries during the premiere eventSimon HumphriesSawadee Krap-here in Thailand and tuning in from around the world. It is a great pleasure to be back here in Bangkok.I would like to begin by expressing, on behalf of Chairman Akio Toyoda and all at Toyota Motor Corporation, our condolences on the passing of Her Majesty Queen Sirikit, The Queen Mother.Toyota has had a close partnership with Thailand for over 60 years. Since the very beginning, this has been not simply an investment, but a partnership. And that partnership has become a friendship.At Toyota, we talk a lot about our "Best in Town" approach, and Thailand is a living embodiment of that philosophy-the first country in Asia outside of Japan where Toyota produced cars.The seed that was planted more than 60 years ago, has been nurtured by the people of Thailand.Thanks to the strong support of the Thai government, our partners and customers, Thailand has become a hub of production, innovation, and above all, collaboration.What we have achieved here is proof that global success comes from local strength. People in 133 countries around the world now benefit from that the fruits of our partnership. More than 13 million vehicles have been produced here.Our Chairman Akio Toyoda knows the strength of that partnership first hand.It was his time working with the team here in Thailand that helped shape that fundamental approach to leadership. Respect for local culture, respect for the importance of shared decision-making.The vehicle that best represents Akio's connection to Thailand, is the IMV project over 20 years ago.The Hilux story began in 1968 but in 2004, under Akio's leadership as head of the ASIA region, Hilux became part of the IMV series―a truly global platform that symbolized Toyota's Best in Town approach, and our monozukuri philosophy. It was the IMV platform that took Hilux global.As the flagbearer of the IMV platform, there is no vehicle that better represents Thailand's importance to Toyota, than Hilux.We are proud to hear that many people even call Hilux Thailand's national vehicle.At Toyota, we have always believed in "Mobility for All."For us, mobility is about giving people the means to explore, to work, to connect-and to improve their lives. From day one, the Hilux project carried this philosophy: to create vehicles that enrich communities and empower people across every continent.For farmers transporting produce, for families heading out on long trips, for workers building the cities around us, Hilux quickly earned a reputation for quality, durability and reliability.Tough enough for construction sites, safe enough for a family road trip, trusted around the world.The new Hilux we announce today is the 9th generation of this legendary vehicle.With each generation, it has only grown stronger: shaped by roads, by engineers, and most importantly, by the voices of customers everywhere.As the world changed, so too did Hilux.Because Toyota listened. We listened to the miners who needed toughness. We listened to families who wanted more comfort.We listened to fleet owners who cared about fuel economy, and to young adventurers who wanted design and technology that matched their lifestyle.Dependable transportation. Connecting people to opportunity with vehicles that were tough, simple, and built to last...Looking ahead, Toyota is pursuing carbon neutrality not with a single solution, but with a multi-pathway approach.Because the truth is simple: no two regions are the same, and no customer is the same.This extends to the powertrain, the body variations and the customizability...all with the aim of leaving nobody behind.Each generation of Hilux has evolved, but the promise is unchanged: Hilux is a partner for life.Ladies and gentlemen, Chairman Akio Toyoda believes that cars, and car making, should not only be part of society and economic prosperity, but a part of culture.For Akio, Thailand is a "home away from home". On a professional level and a personal level, our partnership has become a friendship.He often says that "we want to give back to Thailand". Over the years, our relationship with Thailand has grown beyond economic exchange, to cultural exchange.As president of the International Sumo Federation, Chairman Toyoda found great pleasure in seeing Thailand recently host the Sumo World Championship, bringing Japan's national sport to Thailand for the first time.Although Akio couldn't attend personally, former Yokozuna sumo wrestler Hakuho Sho visited Bangkok.Hakuho is known as the greatest sumo wrestler of all-time. He dominated the world of Sumo for over a decade, winning a record 45 championships...and he's in the Guiness Book of Records for his total of 1,187 career wins...a feat unmatched in sumo's long history. And that's a history of 1,500 years!As a Toyota ambassador, he also stopped by Toyota Motor Thailand.Akio is a former sportsman himself, and over the years he and Hakuho have become friends through their shared passion for nurturing upcoming generations of athletes.In that spirit of friendship, ladies and gentlemen, I would like to welcome back to Thailand, Hakuho!Hakuho, thank you so much for joining us.Hakuho ShoGood morning Thailand, I was just here in September to expand the Sumo to the world. It is great to be back.When Akio suggested that I come to Thailand for this occasion, I said "of course".Thank you again for inviting me to a global launch of a global car, I wish to expand sumo to the same global stage.Sumo is about purity. It's training not only for physical strength but also for mental strength. I believe promoting sumo will deliver hope to resolve discrimination and prejudice around the world.I am originally from Mongolia. And as a Mongolian representing Japan on the world stage, I feel very close to the people of Thailand representing Japan on the world stage through Toyota.Simon HumphriesAs a British person who has spent two-thirds of my life in Japan, I very much agree with that sentiment!History and cultural exchange...now we are going to take it to the next level with the next generation Hilux.I would now like to invite Hakuho to join me in introducing a car that, like a world-leading Sumo wrestler, is strong, sturdy and focused!Ladies and gentlemen, the new Hilux!"Achieving zero, and adding new value beyond it"As part of efforts to pass our beautiful "Home Planet" to the next generation, Toyota has identified and is helping to solve issues faced by individuals and overall society, which Toyota calls "Achieving Zero," hoping to help reduce the negative impacts caused by these issues to people and the environment to zero. Additionally, Toyota is also looking "Beyond Zero" to create and provide greater value by continuing to diligently seek ways to improve lives and society for the future.About Beyond Zero: https://global.toyota/en/mobility/beyond-zero/Toyota Motor Corporation works to develop and manufacture innovative, safe and high-quality products and services that create happiness by providing mobility for all. We believe that true achievement comes from supporting our customers, partners, employees, and the communities in which we operate. Since our founding over 80 years ago in 1937, we have applied our Guiding Principles in pursuit of a safer, greener and more inclusive society. Today, as we transform into a mobility company developing connected, automated, shared and electrified technologies, we also remain true to our Guiding Principles and many of the United Nations' Sustainable Development Goals to help realize an ever-better world, where everyone is free to move.SDGs Initiatives: https://global.toyota/en/sustainability/sdgs/  Copyright 2025 JCN Newswire via SeaPRwire.com. All rights reserved. www.jcnnewswire.com

TOKYO, Nov 10, 2025 - (JCN Newswire via SeaPRwire.com) - Mitsubishi Heavy Industries, Ltd. (MHI) has signed an EPC (Engineering, Procurement and Construction) contract with SC Turkmenhimiya, the state-owned chemical company of Turkmenistan, for the construction of a large-scale ammonia and urea fertilizer production complex. The contract was concluded in partnership with Gap Insaat Yatirim ve Dis Ticaret A.S. (GAP), a leading Turkish contractor. The groundbreaking ceremony was held on November 2, 2025, attended by the President of Turkmenistan, His Excellency Serdar Berdimuhamedov. The plant is scheduled to begin operations in 2030.The project involves the construction of the largest ammonia and urea fertilizer production plant in Turkmenistan. Located on the coastline of the Caspian Sea at Kiyanly in the Balkan province in northwestern Turkmenistan, the project covers basic and detailed design, equipment procurement, construction works, and commissioning of the plant. In addition to the ammonia and urea fertilizer production plant with its associated utilities and offsite facilities, the scope also includes peripheral infrastructure such as temporary piers and product shipment facilities. The planned daily production capacity is 2,000 metric tons of ammonia and 3,500 metric tons of urea. MHI will be responsible for the basic and detailed design, procurement, and commissioning of the ammonia and urea fertilizer plant, and will collaborate closely with GAP and Mitsubishi Corporation to execute the project.Turkmenistan is one of the world's leading countries in natural gas reserves and has prioritized the production of high value-added products using its abundant natural resources and the diversification of export products as key pillars of its national strategy. The fertilizers produced at this plant are expected to greatly contribute to the country's economic growth and enhancement of international competitiveness. Additionally, the plant will be equipped with a CO2 capture facility applying MHI's proprietary "Advanced KM CDR Process™", developed jointly with Kansai Electric Power Co., Inc. This facility will improve plant efficiency and reduce environmental impact, thereby contributing to the realization of a sustainable society.MHI has delivered numerous fertilizer production facilities worldwide since its first plant in 1958. In Turkmenistan, MHI delivered a plant in Garabogaz on the Caspian Sea coast in 2018 in partnership with Mitsubishi Corporation and GAP. This plant has maintained stable operations since its commissioning. This contract award is based on that proven track record as well as a high evaluation of MHI's CO2 capture technology.MHI will continue to strengthen its presence in the global fertilizer plant market and contribute to the world by providing safe and reliable production facilities.About MHI GroupMitsubishi Heavy Industries (MHI) Group is one of the world’s leading industrial groups, spanning energy, smart infrastructure, industrial machinery, aerospace and defense. MHI Group combines cutting-edge technology with deep experience to deliver innovative, integrated solutions that help to realize a carbon neutral world, improve the quality of life and ensure a safer world. For more information, please visit www.mhi.com or follow our insights and stories on spectra.mhi.com Copyright 2025 JCN Newswire via SeaPRwire.com. All rights reserved. www.jcnnewswire.com

TOKYO, Nov 7, 2025 - (JCN Newswire via SeaPRwire.com) - Mitsubishi Heavy Industries, Ltd. (MHI, TSE Code: 7011) announced that order intake increased 8.5% year-on-year to ¥3,314.7 billion in the half year ended September 30, 2025. Revenue rose 7.3% year-on-year to ¥2,113.7 billion, resulting in profit from business activities (business profit) of ¥171.5 billion, a 2.1% increase over the previous fiscal year, which represented a profit margin of 8.1%. Profit attributable to owners of parent (net income) was ¥114.9 billion, an increase of 7.3% year-on-year, with a profit margin of 5.4%. EBITDA was ¥229.6 billion, a 2.5% increase over 1H FY2024, with an EBITDA margin of 10.9%.(billion yen, except where otherwise stated)1H FY2025 Financial Results1H FY2024 (Note)1H FY2025YoYYoY%Order Intake3,054.63,314.7+260.0+8.5%Revenue1,969.22,113.7+144.4+7.3%Profit from Business ActivitiesProfit Margin168.08.5%171.58.1%+3.4-0.4 pts+2.1%-Profit Attributable to Owners of ParentProfit Margin107.15.4%114.95.4%+7.7±0.0 pts+7.3%-EBITDAEBITDA Margin224.111.4%229.610.9%+5.5-0.5 pts+2.5%-FCF-85.7151.0+236.8- - 1H FY2024 results have been retroactively adjusted to reflect the planned sale of Mitsubishi Logisnext (ML) shares. For more information on the ML sale, please refer to the following press releases published on September 30, 2025:1) ML Sale Announcement  2) Revision of FY2025 Earnings Forecast (billion yen, except where otherwise stated)1H FY2025 Financial Results by SegmentOrder IntakeRevenueBusiness Profit1HFY2025YoY (Note)1HFY2025YoY (Note)1HFY2025YoY (Note)Energy Systems (Energy)1,981.2+674.5871.0+38.880.7-22.4Plants & Infrastructure Systems (P&I)490.6-108.7415.9+36.744.6+16.4Logistics, Thermal & Drive Systems (LT&D)292.8-35.9282.4-21.47.6+1.3Aircraft, Defense & Space (ADS)545.0-257.0538.8+107.160.3+16.3Others, Corporate & Eliminations (OC&E)4.9-12.65.4-16.7-21.8-8.3Total3,314.7+260.02,113.7+144.4171.5+3.4 - 1H FY2024 results on which YoY figures are based have been retroactively adjusted to reflect the planned sale of ML shares. In Energy, order intake increased by ¥674.5 billion YoY mainly due to continued strong demand in Gas Turbine Combined Cycle (GTCC). Contracts for 23 large frame gas turbine units—up 14 units YoY—were concluded during 1H, the majority of which were from customers in North America and Asia. Revenue increased by ¥38.8 billion YoY; the largest gains were seen in GTCC, which continued to execute its sizeable backlog. Segment business profit decreased by ¥22.4 billion YoY due to one-time charges in Steam Power, which offset strong performance in GTCC from both higher revenue and margins.In P&I, order intake decreased by ¥108.7 billion YoY due to the absence of large orders booked in the previous fiscal year in Metals Machinery and Machinery Systems. Revenue grew by ¥36.7 billion YoY. Improved margins in Metals Machinery and Machinery Systems helped to raise segment business profit by ¥16.4 billion YoY.In LT&D, revenue decreased by ¥21.4 billion YoY due to a decline in units sold in Turbochargers and Heating, Ventilation & Air Conditioning (HVAC) and foreign exchange impact in HVAC. Steady performance in Engines on the back of strong demand in Asia, combined with the rebound from one-time charges associated with a supply chain disruption in Turbochargers during the previous fiscal year, resulted in a ¥1.3 billion YoY increase in segment business profit.In ADS, order intake decreased by ¥257.0 billion YoY due to a high base effect from large orders booked in Defense & Space during the previous fiscal year. Revenue increased by ¥107.1 billion YoY, mainly in Defense & Space, where steady progress in backlog execution continued. Increased revenue and higher margins in Defense & Space and Commercial Aviation served to increase segment business profit by ¥16.3 billion YoY.FY2025 Earnings ForecastMHI revised its guidance for the period ending March 31, 2026, increasing the forecasts for order intake and revenue over the previous announcement made on September 30, 2025, based on stronger-than-anticipated performance during 1H. The full-year dividend forecast of 24 yen per share was unchanged from the announcement made on August 5, 2025. (billion yen, except where otherwise stated)FY2025 Earnings ForecastFY2024Actual (Note)FY2025Forecast(9/30 Announcement)FY2025Forecast(Revised)Revised vs.PreviousOrder Intake6,405.15,250.06,100.0+850.0Revenue4,361.14,750.04,800.0+50.0Profit from Business ActivitiesProfit Margin354.98.1%390.08.2%390.08.1%--0.1 ptsProfit Attributable to Owners of ParentProfit Margin245.45.6%230.04.8%230.04.8%--ROE10.7%-10%-EBITDAEBITDA Margin469.910.8%--510.010.6%--FCF342.7-0.0-Dividends23 yen-24 yen- - FY2024 results have been retroactively adjusted to reflect the planned sale of ML shares. (billion yen, except where otherwise stated)FY2025 Earnings Forecast by SegmentOrder IntakeRevenueBusiness ProfitPreviousRevisedPreviousRevisedPreviousRevisedEnergy2,200.03,200.01,850.02,000.0240.0240.0P&I900.0900.0850.0850.060.070.0LT&D750.0600.0750.0600.040.020.0ADS1,400.01,400.01,350.01,350.0140.0140.0OC&E0.00.0-50.00.0-90.0-80.0Total5,250.06,100.04,750.04,800.0390.0390.0 CFO Message"The strong growth MHI achieved in the first quarter continued through the first half of this fiscal year, with order intake, revenue, and business profit all up year-on-year, and net income marking an all-time high for the company," MHI Chief Financial Officer Hiroshi Nishio commented. Nishio continued, "GTCC was our star performer in terms of order intake, booking 23 large frame gas turbine units across North America and Asia. We continue to see high demand for gas turbines particularly in the U.S., where new electricity demand from the data center buildout and other factors are driving capital expenditures at our utility customers. Revenue was up especially in GTCC and Defense & Space, which made excellent progress executing on their sizeable backlogs. Business profit growth was small, but the fact that we were able to beat last year's figure—despite one-time expenses recognized in Steam Power—reflects the high normalized margins we are achieving today in GTCC and some other businesses.""Based on our results through the first half," Nishio went on, "we have increased our order intake and revenue forecasts due to better-than-expected results in Energy Systems, mainly GTCC. We have maintained the business profit guidance announced on September 30, with continued strength from growing revenue and improving margins in other businesses compensating for one-time expenses in Energy Systems in excess of the initial 20-billion-yen risk buffer and weakness in the remainder of the Logistics, Thermal & Drive Systems segment. MHI's strong performance despite growing uncertainty in global markets is a testament to our resilience as a company, which has been made possible in part by our continued efforts to evolve our portfolio of businesses. We appreciate the continued support of our shareholders and other stakeholders as we work to meet our full-year commitments during the second half of the fiscal year."Attachment 1: 1H FY2025 Financial ResultsFinancial Results (465 KB)Attachment 2: Presentation Materials of Financial ResultsPresentation Materials (508 KB)Downloadable PDF of this press releasePress Release (164 KB)Forward Looking Statements:Forecasts regarding future performance outlined in these materials are based on judgments made in accordance with information available at the time they were prepared. As such, these projections include risk and uncertainty. Investors are recommended not to depend solely on these projections when making investment decisions. Actual results may vary significantly from these projections due to a number of factors, including, but not limited to, economic trends affecting the Company's operating environment, fluctuations in the value of the Japanese yen to the U.S. dollar and other foreign currencies, and trends in Japan's stock markets. The results projected here should not be construed in any way as a guarantee by the Company.In response to U.S. tariff policy, the Company is pursuing mitigation strategies focused on cost passthroughs. As of the date of this release, the Company expects any impact on performance to be limited in nature.About MHI GroupMitsubishi Heavy Industries (MHI) Group is one of the world’s leading industrial groups, spanning energy, smart infrastructure, industrial machinery, aerospace and defense. MHI Group combines cutting-edge technology with deep experience to deliver innovative, integrated solutions that help to realize a carbon neutral world, improve the quality of life and ensure a safer world. For more information, please visit www.mhi.com or follow our insights and stories on spectra.mhi.com Copyright 2025 JCN Newswire via SeaPRwire.com. All rights reserved. www.jcnnewswire.com

TOKYO, Nov 7, 2025 - (JCN Newswire via SeaPRwire.com) - Mitsubishi Heavy Industries, Ltd. (MHI) has reached a basic agreement with Electric Power Development Co., Ltd. (J-POWER) to commence discussions on the transfer of MHI's domestic onshore wind power business (the "Subject Business") to J-POWER. Upon reaching mutual agreement on the necessary conditions for the transfer, both parties will execute a definitive agreement, aiming to complete the transfer by April 1, 2026.Since initiating the manufacturing of large-scale wind turbines domestically in the 1980s, MHI has accumulated more than 40 years of extensive knowledge and expertise in wind turbine technology. To date, MHI has delivered over 4,200 turbines to 11 countries worldwide, primarily in North America and Japan, and has continuously provided after-sales services. Through this business transfer, MHI aims to fully leverage its specialized expertise across a broader range of fields.J-POWER is committed to balancing stable domestic power supply with addressing climate change by actively developing its wind power business. The J-POWER Group contributes to stable electricity supply and is also pursuing carbon neutrality, as outlined in the J-POWER "BLUE MISSION 2050" announced in February 2021.(Note) Wind power has been a core focus for J-POWER since it was among the first in Japan to operate a large-scale commercial wind farm in 2000, and it currently holds the second-largest domestic market share in wind power generation facilities.The transfer of the Subject Business will strengthen and further expand J-POWER's foundation as a wind power developer by integrating MHI's accumulated wind power expertise. This collaboration is expected to accelerate the future expansion of J-POWER's wind power business and related services, leading to further growth. MHI is convinced that this will not only provide customers with greater value but also offer new opportunities for growth and development to employees engaged in this business.MHI Group will continue to optimize its business organization in line with the policy of strengthening portfolio management set out in the 2024 Medium-Term Business Plan.For more information, please visit: https://www.jpower.co.jp/english/bluemission2050/Notice Regarding the Conclusion of a Basic Agreement Concerning the Transfer of Business to a Subsidiary via Company Split (Simplified Absorption-type Split) and the Transfer of Shares in Said Subsidiary (272KB)About MHI GroupMitsubishi Heavy Industries (MHI) Group is one of the world’s leading industrial groups, spanning energy, smart infrastructure, industrial machinery, aerospace and defense. MHI Group combines cutting-edge technology with deep experience to deliver innovative, integrated solutions that help to realize a carbon neutral world, improve the quality of life and ensure a safer world. For more information, please visit www.mhi.com or follow our insights and stories on spectra.mhi.com Copyright 2025 JCN Newswire via SeaPRwire.com. All rights reserved. www.jcnnewswire.com

TOKYO, Nov 7, 2025 - (JCN Newswire via SeaPRwire.com) - The Japan Foundation of Cancer Research (JFCR) and NEC Corporation (NEC; TSE: 6701) have confirmed research results supporting the development of a novel personalized neoantigen cancer vaccine using whole-genome data (*1). Analysis utilizing NEC's proprietary AI technology from breast cancer and soft tissue sarcoma has successfully enabled the prediction of numerous cancer-specific antigens (cryptic antigens, *2) originating from dark genomes—regions of the genome whose function and role remain largely unexplored—in addition to conventional neoantigens (*3). Developing vaccines using these antigens could potentially offer new treatment options for cancers that have been difficult to treat until now.Both organizations will present these findings at the annual meeting of the Society for Immunotherapy of Cancer (SITC), held in National Harbor, Maryland, USA, from Wednesday, November 5 to Sunday, November 9, 2025.This joint research project will be carried out as part of the Japan Agency for Medical Research and Development (AMED)’s "Action Plan for Whole-Genome Analysis for Cancer and Rare/Intractable Diseases," within the research initiative on the "Demonstration of the Clinical Utility of Cancer Whole-Genome Analysis and Research on Establishing Systems for Patient Benefit".In recent years, personalized medicine—aiming for more effective and optimal treatments based on each patient's genomic information and gene expression profiles—has garnered significant attention. Among these approaches, immunotherapy using personalized cancer vaccines that target neoantigens specific to each patient's cancer cells is especially promising for practical application due to its potential for high therapeutic efficacy and reduced side effects. In Japan, efforts to promote research and drug discovery utilizing whole-genome analysis data are accelerating, as demonstrated by the Ministry of Health, Labour and Welfare's formulation of the "Action Plan for Whole Genome Analysis 2022" (*4). Against this backdrop, the Cancer Institute and NEC have been collaborating since 2024 on the development of a novel personalized neoantigen cancer vaccine utilizing whole-genome analysis data.The prevalence of neoantigens is known to vary across cancer types. In this study, the Cancer Institute and NEC analyzed whole-genome data from breast cancer and soft tissue sarcoma, which are considered to have relatively low neoantigen emergence rates, utilizing NEC's proprietary AI technology. This study sought to demonstrate that integration of whole genome data allows the identification of relevant immunogenic targets, even in patients with cancer associated with a low number of canonical antigens.The collaborative research successfully predicted the presence of numerous non-canonical antigens, in addition to previously known classes of antigen targets. Developing vaccines utilizing these findings is expected to open new therapeutic approaches for cancer types that have traditionally been considered difficult to treat with personalized neoantigen cancer vaccines."We are delighted to share the findings of our basic research aimed at developing next-generation personalized cancer vaccines. This work was conducted under an AMED research program based on the Action Plan for Whole-Genome Analysis 2022 (Ministry of Health, Labour and Welfare). By integrating whole-genome data with NEC’s proprietary AI technology, we have revealed the potential presence of diverse cancer-specific antigens, known as cryptic antigens, derived from the dark genome even in cancer types previously considered to have limited neoantigen expression. Moving forward, we will continue to evaluate the immunogenicity of these antigens and advance the development of personalized cancer vaccines to realize the next generation of cancer immunotherapy."Tetsuo Noda, M.D., Ph.D., Advisor, Atsushi Ohtsu, M.D., Ph.D., Research Director, Japanese Foundation for Cancer Research"We are pleased to share our research findings on cryptic antigens, developed in collaboration with JFCR. This work, which utilizes whole-genome data and NEC's proprietary AI technology, will be presented at the SITC Annual Meeting as part of a project supported by AMED. Going forward, the NEC Group remains committed to advancing our mission of delivering innovative AI-powered healthcare solutions to patients around the world."Motoo Nishihara, Executive Officer, Corporate EVP and CTO, NECPresentation DetailsAbstract Number: 162Title: A Whole-Genome-Informed Pipeline for Neoantigen Discovery in Solid Tumors: Integrating SNV, Splice Variant, and Exon-Transposon Junction Analysis to Enable Personalized Cancer VaccinesPresenters: Jun MasudaAuthors: Jun Masuda1, Kazuma Kiyotani2, Kazuhide Onoguchi3, Per Brattås4, Hugues Fontenelle4, Angelina Sverchkova4, Sumana Kalyanasundaram4, Pierre Machart5, Yuki Tanaka3, Daiki Miura3, Noboru Nagata3, Koji Yoshino1, Mingyon Mun1, Yasuji Miyakita1, Hiroki Mitani1, Souya Nunobe1, Yu Takahashi1, Hiroyuki Kanao1, Takashi Akiyoshi1, Keisuke Ae1, Kengo Takeuchi1, Junji Yonese1, Masayuki Watanabe1, Seiichi Mori6, Seiya Imoto7, Ippei Fukada1, Shunji Takahashi1, Takayuki Ueno1, Noboru Yamamoto8, Kaïdre Bendjama4, and Shigehisa Kitano1Affiliation: 1) The Cancer Institute Hospital of Japanese Foundation for Cancer Research, Tokyo, Japan. 2) National Institutes of Biomedical Innovation, Health and Nutrition, Osaka, Japan. 3) NEC Corporation, Tokyo, Japan. 4) NEC OncoImmunity AS, Oslo, Norway. 5) NEC Laboratories Europe GmbH, Heidelberg, Germany. 6) Japanese Foundation for Cancer Research, Tokyo, Japan. 7) The Institute of Medical Science, the University of Tokyo, Tokyo, Japan. 8) National Cancer Center Hospital, Tokyo, Japan.Release Date: November 8, 2025(*1) Genome analysis includes: 1.methods targeting only specific genomic regions called coding regions, and 2.methods targeting both coding and non-coding regions. In this study, whole-genome data analysis (corresponding to 2.) was performed on samples provided by cancer patients.(*2) A type of neoantigen; a cancer antigen originating from non-coding regions of the genome that do not encode proteins.(*3) Refers to "cancer-specific antigens (markers)" newly generated by genetic mutations in cancer cells. Since they are absent in healthy cells and appear only in cancer cells, the immune system can recognize them as foreign substances and target them for attack.(*4) A plan formulated as a national strategy primarily to advance genome analysis in the medical field. Its objectives include developing new diagnostics and treatments for cancers and rare/intractable diseases, as well as promoting the realization of personalized medicine.About Japanese Foundation for Cancer ResearchJapanese Foundation for Cancer Research (JFCR) was founded in 1908 as the first organization in Japan specialized for study and control of cancer. JFCR has been playing a leading role in cancer research and treatment for a long time. We have three research centers and a hospital, which are "Cancer Institute" for basic cancer research, "Cancer Chemotherapy Center" for drug development, "Cancer Precision Medicine Center" (CPM Center) and "Cancer Institute Hospital of JFCR" for development of novel cancer treatments. These centers and a hospital are working together to achieve our common goal which is cancer control.About NECThe NEC Group leverages technology to create social value and promote a more sustainable world where everyone has the chance to reach their full potential. NEC Corporation was established in 1899. Today, the NEC Group's approximately 110,000 employees utilize world-leading AI, security, and communications technologies to solve the most pressing needs of customers and society. For more information, please visit https://www.nec.com, and follow us on Instagram, Facebook, and LinkedIn.  Copyright 2025 JCN Newswire via SeaPRwire.com. All rights reserved. www.jcnnewswire.com

TOKYO, Japan, Nov 7, 2025 - (JCN Newswire via SeaPRwire.com) - NEC Corporation (NEC; TSE: 6701) is sponsoring the NEC Wheelchair Singles Masters*1 scheduled to be held from November 10 (Monday) to November 16 (Sunday) in the city of Huzhou in China’s Zhejiang Province.This tournament is the year-end singles championship on the UNIQLO Wheelchair Tennis Tour (comprised of more than 160 tournaments) hosted by the International Tennis Federation (ITF*2), bringing together the world’s top-ranked players to engage in elite competition.The partnership between NEC and the ITF has endured over 30 years, beginning when NEC first served as the title sponsor of the Wheelchair Tennis Tour in 1992. NEC has sponsored this tournament since its establishment in 1994, and this year marks the first time the historic tournament has been held in Asia.Through the support of parasports, including this sponsorship and its partnership with wheelchair tennis legend Shingo Kunieda, NEC is contributing to the creation of inclusive and diversified environments where everyone has a chance to reach their full potential.Plans are slated for Japan’s Tokito Oda and Yui Kamiji, the number-one-ranked men’s and women’s singles players in the world, respectively, to compete in the tournament.David Haggerty, ITF President, said: "We are thrilled to bring the Wheelchair Masters to China for the first time, marking an important milestone in our mission to grow the sport globally. As the flagship, season-ending event, the Wheelchair Masters showcase the very best in wheelchair tennis. NEC, as title sponsor since 1994, has been instrumental in supporting wheelchair tennis from the very start, and we are grateful for their long-standing commitment. Taking place at the new, world-class Huzhou International Clay Tennis Center, it’s exciting to see top Chinese players, including Wang Ziying and Li Xiaohui, 2025 Australian Open and Wimbledon women’s doubles champions, competing alongside the world’s leading international athletes. This event is a fantastic opportunity to inspire the next generation of wheelchair players both globally and across Asia, and we encourage everyone to follow the action as it promises to be an incredible week of wheelchair tennis.""NEC is once again delighted to be supporting one of the world’s most prestigious competitions," said Takayuki Morita, President and CEO of NEC Corporation. "This year marks a memorable milestone as the tournament is being held in Asia for the first time, with China serving as its host. Over the past several decades, wheelchair tennis has evolved and grown in popularity, and I take great pride in the fact that NEC has been involved in the development of this sport since its inception. The NEC Group remains committed to pursuing its Purpose*3 and contributing to the creation of inclusive and diversified environments where everyone has a chance to reach their full potential."Overview of the 2025 NEC Wheelchair Singles Masters1. DateNovember 10 – 16, 20252. VenueHuzhou International Clay Tennis Center (Huzhou, Zhejiang, China)3. HostInternational Tennis Federation (ITF)4. SponsorNEC5. PlayersThe world’s top eight ranked men’s, women’s, and quad players (*1) International Tennis Federation (ITF) https://www.itftennis.com/The ITF is the international governing body for tennis, headquartered in the outskirts of London. The ITF Wheelchair Tennis Department, comprised of wheelchair tennis associations from approximately 60 countries worldwide, including Japan, manages and grades wheelchair tennis tournaments, establishes world rankings and prize systems, and carries out activities to promote wheelchair tennis. The ITF wheelchair tennis tournaments are said to be the most systematized events for Para athletes in the world.(*2) NEC Wheelchair Singles MastersThis year-end championship for wheelchair tennis (singles) is held around November every year. The top eight players in the men’s, women’s, and quad categories are eligible to participate and compete for prestigious titles. NEC has supported this event since the first tournament was held in 1994.(*3) The NEC Group’s PurposeNEC creates the social values of safety, security, fairness and efficiency to promote a more sustainable world where everyone has the chance to reach their full potential.To learn more about NEC Wheelchair Tennis Sponsorship, please click on the URL below.https://www.nec.com/en/global/ad/wheelchairtennis/index.htmlAbout NEC CorporationNEC Corporation has established itself as a leader in the integration of IT and network technologies while promoting the brand statement of "Orchestrating a brighter world." NEC enables businesses and communities to adapt to rapid changes taking place in both society and the market as it provides for the social values of safety, security, fairness and efficiency to promote a more sustainable world where everyone has the chance to reach their full potential. For more information, visit NEC at https://www.nec.com.  Copyright 2025 JCN Newswire via SeaPRwire.com. All rights reserved. www.jcnnewswire.com

PALO ALTO, CA, Nov 7, 2025 - (JCN Newswire via SeaPRwire.com) - NEC X, the Silicon Valley venture studio backed by NEC Corporation’s (NEC; TSE: 6701) advanced technologies and global businesses, today announced a strategic investment in Indicio, an innovative startup revolutionizing digital trust by enabling people, organizations, connected devices, and AI agents to control cryptographically verifiable digital identities and share instantly-verifiable data.The investment supports Indicio’s participation in NEC X's Elev X! Boost program, which is designed to fast-track tech development and adoption for promising startups.Indicio’s platform and specialized encryption technology addresses critical vulnerabilities in traditional, centralized identity systems, which are prone to data breaches, privacy violations and forgery. These outdated models require people to repeatedly share sensitive data, increasing risks and creating costly administrative burdens for banks, government operations and enterprises.The self-sovereign identity (SSI) market is projected to reach $47.1 billion by 2029, with 500 million smartphone users expected to adopt decentralized identity wallets by 2026. Recognized by Gartner and Juniper Research firms as a market leader in Decentralized Identity, Indicio enables organizations to meet the growing demand for secure, privacy-preserving digital interactions and decentralized infrastructure."We are honored to join NEC X," said Heather Dahl, CEO of Indicio, "and to see our innovation in digital identity authentication and access management, biometrics, AI, seamless digital travel and border management recognized by such a technology leader as NEC X. We see decentralization and verifiable digital identity as the foundation for building the next era of the internet, and for scaling new digital markets and autonomous digital systems. The ability to instantly authenticate any entity and share trusted data securely and in a privacy-preserving way will be a tremendously powerful ‘algorithm’ that synergizes economic growth, business integration, and consumer trust. It will also be critical to successfully deploying autonomous systems that use AI."Being part of NEC X’s Elev X! program will inform, inspire, and above all, accelerate, our work in making this new, better, simpler and safer digital world a reality."NEC X's Elev X! Boost program provides startups with strategic funding, cutting-edge technology access and business resources to accelerate their growth. Indicio will leverage NEC X’s investment and NEC’s world-class biometric authentication technologies to develop new solutions for applications like trusted AI, streamlined travel and secure access management."Indicio’s vision for a user-controlled internet aligns perfectly with NEC X’s commitment to fostering disruptive technologies that solve fundamental global challenges," said Shintaro Matsumoto, CEO of NEC X. "Their leadership in decentralized identity is creating the foundational layer for a more trusted and secure digital future. We are excited to support their journey as they redefine the standards for digital interaction and data privacy."Indicio is already gaining significant market traction. In a pioneering use case with SITA and the Government of Aruba, the company’s technology enables travelers to enter the country using a secure digital travel credential on their smartphone instead of a physical passport. The company's technical excellence has also been recognized with multiple awards, including the EIC Award 2022 and selection as a finalist in the DHS Digital Design Challenge 2020.Indicio provides the technology and services for enterprises to build and deploy decentralized identity solutions across travel, finance, enterprise applications, education and more. Looking ahead, the company is building the infrastructure for a new era of digital trust, extending verifiable identity to AI agents and connected devices to ensure secure, permissioned data access and interaction.For more information on Indicio, visit https://indicio.tech.About IndicioIndicio provides everything needed to build efficient, powerful, and simple, decentralized solutions for a new era of digital trust. With Indicio Proven, travel, hospitality, financial services, and enterprise customers can integrate portable, authenticated biometric credentials into existing workflows enabling seamless border crossing, rapid, remote KYC, and protection against synthetic identity fraud and deepfakes — without requiring biometric data to be stored.Indicio Proven’s Verifiable Credential technology delivers seamless efficiency and transformative security. Data can be shared and verified without direct integrations. Authentication no longer depends on centralized databases, passwords, or third-party identity providers. Verifiable digital identities can be assigned to connected devices, robots, and AI agents, providing the mutual authentication, permissioned data access, and secure interaction needed for these critical technologies to maximize their potential and benefits. By making trusted data and identity the engine of growth, Indicio delivers secure, interoperable solutions that reduce friction, cut costs, and scale markets. For more info, visit https://indicio.tech/About NEC XNEC X is an innovation powerhouse and curator of disruptive startups backed by the global technology leadership of NEC. Leveraging 125 years of IT and network technologies expertise, NEC X’s startup-focused approach transforms visionary ideas into commercial successes that revolutionize how we work and live. Since its inception in 2018, NEC X has helped launch and grow more than 180 startups.Their Silicon Valley programs – Elev X! Ignite and Elev X! Boost – equip early-stage startup founders with the tools to fast-track their tech development and adoption. Elev X! fuels startup success from inception to launch, connecting innovators with NEC’s 45,000 patents; global network of partners, mentors and advisors; reach into 55+ international markets; and $8 billion R&D ecosystem.For more information, visit https://nec-x.com and https://www.elev-x.com.About NEC CorporationNEC Corporation has established itself as a leader in the integration of IT and network technologies while promoting the brand statement of “Orchestrating a brighter world.” NEC enables businesses and communities to adapt to rapid changes taking place in both society and the market as it provides for the social values of safety, security, fairness and efficiency to promote a more sustainable world where everyone has the chance to reach their full potential. For more information, visit NEC at https://www.nec.com. Copyright 2025 JCN Newswire via SeaPRwire.com. All rights reserved. www.jcnnewswire.com