日期: 2026 年 4 月 23 日

SHENZHEN, Apr 23, 2026 - (ACN Newswire via SeaPRwire.com) - China Medical System Holdings Limited (the “Group” or “CMS”) is pleased to announce that the New Drug Application (NDA) in China for the Seasonal Allergic Rhinitis (SAR) indication of MG-K10 (generic name: Comekibart Injection, “MG-K10” or the “Product”), a Class 1 innovative drug anti-IL-4Rα humanized monoclonal antibody injection, for which the Group holds co-development rights (excluding the indication of atopic dermatitis (AD)) and exclusive commercialization rights, was accepted by the National Medical Products Administration of China (NMPA) on 23 April 2026. The Product is proposed for the treatment of adult patients with moderate-to-severe seasonal allergic rhinitis whose symptoms remain inadequately controlled after treatment with intranasal corticosteroids.The acceptance of the NDA represents an important milestone for the Group’s ophthalmology business, CMS Vision, as it expands its therapeutic focus from ophthalmology into the field of otolaryngology (ENT). It also marks another significant milestone in the Group’s research and development progress in the field of type 2 inflammatory diseases. If the Product is successfully approved for marketing, the Group will leverage its strong academic promotion capabilities and extensive commercialization network to accelerate the commercialization of the Product. It is also expected to further enhance the academic brand influence of CMS Vision in the relevant specialty areas and provide new momentum for the Group’s business growth.BIC Potential: Dosing once every 4 weeks; Phase III study met the primary endpoint with a favorable safety profileMG-K10 is an innovative long-acting anti-IL-4Rα humanized monoclonal antibody that simultaneously blocks the signaling pathways of the key type 2 inflammatory cytokines IL-4 and IL-13, thereby exerting immunomodulatory effects. It is being developed for the treatment of type 2 inflammatory diseases, including seasonal allergic rhinitis, asthma, atopic dermatitis (AD), prurigo nodularis, chronic obstructive pulmonary disease (COPD), chronic spontaneous urticaria (CSU), chronic rhinosinusitis with nasal polyps, and eosinophilic esophagitis. Currently marketed anti-IL-4Rα therapies require administration once every two weeks. MG-K10, with its longer half-life, enabling a once-every-four-weeks dosing regimen. It therefore has the potential to become the first long-acting anti-IL-4Rα monoclonal antibody to be marketed globally, with the potential to be best-in-class. MG-K10 has met the primary endpoint in a multicenter, randomized, double-blind, placebo-controlled Phase III clinical trial in adult patients with moderate-to-severe seasonal allergic rhinitis. The results of the Phase III study demonstrated that the primary endpoint achieved statistical significance, with significantly superior efficacy compared with the placebo group, and a favorable safety profile.Focusing on Unmet Needs: ~250 million patients; 62% of moderate-to-severe patients remain inadequately controlled; long-acting breakthrough brings new treatment opportunitiesAllergic rhinitis is a chronic inflammatory disease of the nasal mucosa mediated by IgE, with type 2 inflammation as the core pathogenic mechanism. It occurs in susceptible individuals upon exposure to environmental allergens such as pollen and dust mites. In recent years, the prevalence of the disease in China has increased from 11.1% to 17.6%, affecting approximately 250 million people[1], among whom 52.2% are patients with persistent moderate-to-severe disease[2]. The disease burden is significant and has become an important public health issue. Current standard treatments, including intranasal corticosteroids and antihistamines, have notable limitations. 62% of patients with moderate-to-severe disease remain inadequately controlled[3]. Long-term use of intranasal corticosteroids may lead to adverse reactions such as epistaxis[4], while antihistamines are often associated with side effects such as drowsiness[5], indicating significant unmet clinical needs. As a biologic therapy targeting IL-4Rα, MG-K10 can block the type 2 inflammatory pathway at its source. Compared with currently approved biologics targeting the same pathway (which require dosing once every two weeks), MG-K10 achieves a differentiated breakthrough in dosing frequency with its long-acting property allowing administration once every four weeks, thereby significantly extending dosing intervals. This may help improve patient treatment adherence and reduce the time and economic burden associated with frequent hospital visits. The Product has the potential to provide a new treatment option for patients with moderate-to-severe disease who respond poorly to conventional therapies, thereby reducing the individual and socio-economic burden associated with the disease.On 24 January 2025, the Group through subsidiaries of the Company entered into a Collaboration Agreement (“Agreement”) with Hunan Mabgeek Biotech Co., LTD and its subsidiary for MG-K10. In accordance with the Agreement and supplementary agreements, the Group has obtained the co-development rights (excluding AD) and exclusive commercialization rights for the Product in Mainland China, Hong Kong Special Administrative Region, Macao Special Administrative Region, Taiwan Region and Singapore; its subsidiary Dermavon Holdings Limited has obtained, through its subsidiary, the co-development rights (excluding AD) and exclusive commercialization rights for the Product in the field of dermatological indications in Mainland China.About CMSCMS is a platform company linking pharmaceutical innovation and commercialization with strong product lifecycle management capability, dedicated to providing competitive products and services to meet unmet medical needs.CMS focuses on the global first-in-class (FIC) and best-in-class (BIC) innovative products, and efficiently promotes the clinical research, development and commercialization of innovative products, enabling the continuous transformation of scientific research into clinical practices to benefit patients.CMS deeply engages in several specialty therapeutic fields, and has developed proven commercialization capabilities, extensive networks and expert resources, resulting in leading academic and market positions for its major marketed products. CMS continues to promote the in-depth development in its advantageous specialty fields, strengthening the competitiveness of the Cardiovascular-Kidney-Metabolic/ gastroenterology/ ophthalmology/ skin health businesses, bringing economies of scale in specialty fields. Among them, the skin health business (Dermavon) has become a leading enterprise in its field, and is proposed to be listed independently on the SEHK. Meanwhile, CMS continuously promotes the operation and development of its integrated R&D, manufacturing and commercialization chain in Southeast Asia and the Middle East, capturing growth opportunities in emerging markets to support the high-quality and sustainable development of the Group.Reference1. Cheng L, Chen J, Fu Q, et al. Chinese Society of Allergy Guidelines for Diagnosis and Treatment of Allergic Rhinitis. Allergy Asthma Immunol Res. 2018;10:300‑353.2. Zheng, Ming et al. “Clinical characteristics of allergic rhinitis patients in 13 metropolitan cities of China.” Allergy vol. 76,2 (2021): 577-581. doi:10.1111/all.145613. White, P et al. “Symptom control in patients with hay fever in UK general practice: how well are we doing and is there a need for allergen immunotherapy?” Clinical and experimental allergy : journal of the British Society for Allergy and Clinical Immunology vol. 28,3 (1998): 266-70. doi:10.1046/j.1365-2222.1998.00237.x4. Rosenblut, A et al. “Long-term safety of fluticasone furoate nasal spray in adults and adolescents with perennial allergic rhinitis.” Allergy vol. 62,9 (2007): 1071-7. doi:10.1111/j.1398-9995.2007.01521.x5. Bernstein, Jonathan A et al. “Allergic Rhinitis: A Review.” JAMA vol. 331,10 (2024): 866-877. doi:10.1001/jama.2024.0530CMS Disclaimer and Forward-Looking StatementsThis press release is not intended to promote any products to you and is not for advertising purposes. This press release does not recommend any drugs, medical devices and/or indications. If you want to know more about the diagnosis and treatment of specific diseases, please follow the opinions or guidance of your doctor or other medical and health professionals. Any treatment-related decisions made by healthcare professionals should be based on the patient’s specific circumstances and in accordance with the drug package insert.This press release which has been prepared by CMS does not constitute any offer or invitation to purchase or subscribe for any securities, and shall not form the basis for or be relied on in connection with any contract or binding commitment whatsoever. This press release has been prepared by CMS based on information and data which it considers reliable, but CMS makes no representation or warranty, express or implied, whatsoever, and no reliance shall be placed on, the truth, accuracy, completeness, fairness and reasonableness of the contents of this press release. Certain matters discussed in this press release may contain statements regarding the Group’s market opportunity and business prospects that are individually and collectively forward-looking statements. Such forward-looking statements are not guarantees of future performance and are subject to known and unknown risks, uncertainties and assumptions that are difficult to predict. Any forward-looking statements and projections made by third parties included in this press release are not adopted by the Group and the Company is not responsible for such third-party statements and projections.Media ContactBrand: China Medical System Holdings Ltd.Contact: CMS Investor RelationsEmail: ir@cms.net.cnWebsite: https://web.cms.net.cn/en/home/ Copyright 2026 ACN Newswire via SeaPRwire.com. All rights reserved. www.acnnewswire.com

HONG KONG, Apr 23, 2026 - (ACN Newswire via SeaPRwire.com) - The 3rd Smart Lighting Expo and the 17th Hong Kong International Lighting Fair (Spring Edition), organised by the Hong Kong Trade Development Council (HKTDC), successfully concluded today at the Hong Kong Convention and Exhibition Centre. The four-day fairs brought together some 900 exhibitors and attracted some 13,000 buyers from 114 countries and regions for on-site visits and sourcing. Buyer numbers recorded growth, including those from Asian markets such as Malaysia and the Philippines; European markets including France, Germany, the Netherlands, Russia and Türkiye; and North and South American markets, including Brazil, Canada and the US, highlighting Hong Kong’s role as a key global hub for lighting products and technology exchange.Jenny Koo, Deputy Executive Director of the HKTDC, said: "This year’s two lighting fairs attracted industry-leading enterprises who showcased cutting-edge high-performance, smart lighting and sustainable products and solutions. The events also attracted quality buyers from global markets. This helps companies diversify supply chains, explore new markets, and underscores Hong Kong’s strength as an ‘International Exhibition Capital’ which boosts efficient business platforms. The fairs are the preferred platform for the industry to showcase innovation, connect with global buyer networks and accelerate business development.”Survey findings: Respondents were most optimistic about the India and Australia marketsTo keep abreast of the latest industry developments, the HKTDC conducted an on-site survey during the fairs, interviewing 450 exhibitors and buyers. The findings show that overall confidence among exhibitors and buyers in future business development has shown a general increase.Key market outlook and product trend findings:49.1% of respondents expect overall sales to increase in the next 12 to 24 months, while 47.6% expect sales to remain stable.Respondents consider India (73.4%), Australia (71%), ASEAN countries (70.4%), and Japan (68.1%) to be promising or very promising target sales markets for lighting products over the next two years in terms of growth.In terms of new market development, exhibitor respondents are actively exploring Middle East (31.8%), Europe (29.5%), ASEAN countries (23.9%), Latin America (17.6%) and North America (14.8%).In the smart lighting segment, respondents identified home automation and intelligent lighting control systems (48.2%), energy saving lighting control solutions (38.2%), and outdoor smart security lighting systems (31.1%) as having the greatest growth potential over the next two years.Compared with conventional lighting products, respondents indicated that consumers are willing to pay an average premium of 29% for lighting products equipped with smart functions.Scenario-based displays and new zones enhance sourcing effectiveness, with positive trade outcomesThe newly launched “Light Lab” features various scenario-based and immersive designs, integrating lighting products into landscape, sports, cultural and artistic application settings. Shanghai Sansi Electronic Engineering showcased plant clamp lights and compact downlights suitable for museum applications. Guoli Zhu, Deputy Chief Engineer of the company said: “The Light Lab has effectively enhanced the presentation of our products, enabling buyers to more intuitively and swiftly grasp product features and their real-world application scenarios. This has successfully attracted buyers from Argentina, Canada, Germany, India, Japan and the US to visit our booth for in-depth discussions. We expect this to result in orders worth over US$1 million.”The Smart Lighting Expo also debuted the “Smart Display and Stage Lighting & Sound Zone” which displayed a wide range of intelligent display solutions. Industry leader Absen participated in the fair for the first time. Benjamin Tang, Senior Sales Engineer, said: “The new zone has effectively enhanced product visibility, attracting buyers from Eastern Europe, Oceania, North America, South America, and South Asia to our booth. These inquiries came from new clients across key sectors such as cultural tourism and stage engineering. We have also successfully engaged in several promising collaboration discussions with potential clients from the Dominican Republic, Hong Kong and Thailand, further strengthening the company’s market expansion plan. We estimate the value of orders from the expo will amount to US$930,000. Riding on this momentum, we have decided to join the Hong Kong International Lighting Fair (Autumn Edition) this year.”The newly launched “Leisure Lighting Zone” has injected new momentum into the Spring Lighting Fair. Rebecca Seo, CFO of NIZ, a first-time exhibitor from Korea, said: “The fair has provided us with an excellent platform to connect with international buyers. We have successfully connected with buyers from Denmark, Germany, Japan, and the US, and a well-known Japanese homeware retailer has already placed an on-site order. Thanks to the strong traffic generated by the new zone, we expect the fair to bring up to US$70 million in orders for our company this year."Supported by Zhongshan as the Special Partner City, the fairs featured the Zhongshan Guzhen Pavilion and Zhongshan Henglan Pavilion under the Zhongshan Smart Home Zone, presenting the manufacturing strength and competitiveness of the region’s lighting industry while supporting enterprises in “going global”. Merry Liu, Manager of Bairan Lighting, an industrial enterprise above designated size in Henglan, Zhongshan, said: “The two lighting fairs provide Zhongshan enterprises with an efficient ‘go-global’ gateway, enabling us to connect directly with buyers from Europe, the Middle East, South America, and Southeast Asia. This helps drive our products and brand onto the international stage. We expect to achieve US$2 million in sales.”During the fair, the HKTDC organised a buying mission to Zhongshan for the first time, visiting several lighting factories and participating in business matching meetings. This initiative aimed to deepen exchange and cooperation within the Zhongshan lighting supply chain. The visit successfully facilitated several substantive business collaborations; New Zealand buyer Spark100 Ltd established a connection with a Zhongshan lighting supplier, with a potential order value estimated between US$100,000 and US$300,000.This year’s exhibition also attracted buyers from the Middle East. Patrick Zhang, VP of sales of Tecnon Lighting Technology from the Shenzhen Pavilion, stated: “At this year’s fair, a buyer from the United Arab Emirates and a US buyer from a leading women’s fashion brand are likely to become our cooperation partners. We expect to generate US$2 million in sales turnover for our company.”As construction projects in the ASEAN region accelerate, market demand for smart lighting solutions continues to expand. Sambath HK, Manager of RS Decoration from Cambodia, stated, “I travelled here specifically to source lighting products for 14 new commercial building and luxury residential projects. I have already met with over 20 new suppliers and identified two potential partners offering smart street lights, solar lights, and decorative lighting products. I will initially purchase US$100,000 worth of smart street lights.”Driven by the Belt and Road Initiative, urban development in participating countries and regions are in full swing, fuelling a continuous surge in demand for high-efficiency and smart lighting products. Aigerim Beisekina, Supply Manager of Karelz.kz from Kazakhstan, said: “This is our first time visiting the twin lighting fairs, to find reliable suppliers for a solar-powered stadium and sports lighting for three international schools currently under construction in Kazakhstan. Through the Click2Match business matching platform, we have identified three potential suppliers from the Chinese Mainland and plan to purchase lighting equipment valued between US$600,000 and US$900,000.”During the fairs, multiple professional events were held, including the Asian Lighting Conference and the Smart Lighting Solutions Forum. Designers and industry representatives from different regions shared market trends, application cases and technological developments, providing forward-looking market insight for the industry.EXHIBITION+ model sustains post-fair business opportunitiesUnder the hybrid EXHIBITION+ model, the twin lighting fairs combined in-person sourcing with online meetings via the HKTDC’s Click2Match smart business-matching platform and hktdc.com sourcing platform. Click2Match will be available until 30 April to facilitate discussions between exhibitors and buyers around the world.Photo download:  https://bit.ly/42m6sqDThe 3rd Smart Lighting Expo and the 17th Hong Kong International Lighting Fair (Spring Edition), organised by the Hong Kong Trade Development Council (HKTDC), successfully concluded today at the Hong Kong Convention and Exhibition Centre, attracted some 13,000 buyers from 114 countries and regions for on-site visits and sourcing.The newly launched “Light Lab” adopted a series of scenario-based and immersive designs, integrating lighting products directly into landscape, sports, cultural and artistic application settings, enabling buyers to better understand product features and practical applications.At the Spring Lighting Fair, the featured “Hall of Aurora” brought together 120 international and premium lighting brands, attracting numerous global buyers.The Shanghai Pudong Intelligent Lighting Association also returned to the Smart Lighting Expo for the third consecutive year, presenting the “Intelligent Ecosystem & IoT Supply Chain Zone”.As for the Spring Lighting Fair, exhibitors include the Xiamen Pavilion, and newly participating Changzhou Zouqu District Pavilion and Zhejiang Pavilion, further broadening industry exchange.The two fairs gathered numerous renowned brands and industry leaders, including Absen (photo), an LED display provider featured at the NBA All-Stars Games, the FIFA Qatar World Cup and Qatar Doha World Expo, and a Guinness World Record holder; and Shanghai Sansi, which supplies over 60% of the display screens in Times Square, New York.During the fairs, the HKTDC arranged various matching activities to connect buyers and exhibitors. The photo shows buyer Powermep from the UAE in discussion with an exhibitor.During the fairs, the HKTDC organised a buying mission to Zhongshan for the first time, visiting several lighting factories and participating in business matching meetings, strengthening exchange and cooperation within the Zhongshan lighting supply chain.‍The Smart Lighting Solution Forum was held on 21 April. Industry experts shared developments in smart home lighting systems and human-centric lighting for home entertainment as well as discussion of the eco-system of health and connected lighting supply chains.As part of the city’s mega-event economy, the Hong Kong Tourism Board (official exhibition promotion partner) arranged special “Cheung Po Tsai” Victoria Harbour night cruises during the fairs to enhance the business travel experience of convention and exhibition visitors.WebsitesHong Kong International Lighting Fair (Spring Edition): hklightingfairse.hktdc.com/tcSmart Lighting Expo: smartlightingexpo.hktdc.com/tcHKTDC Mediaroom: http://mediaroom.hktdc.com/enMedia enquiriesHKTDC’s Communications & Public Affairs Department:Stanley So Tel: (852) 2584 4049 Email: stanley.hp.so@hktdc.orgNavin Law Tel: (852) 2584 4525  Email: navin.cm.law@hktdc.orgSerena Cheung Tel: (852) 2584 4272 Email: serena.hm.cheung@hktdc.orgAbout HKTDCThe Hong Kong Trade Development Council (HKTDC) celebrates its 60th anniversary this year. The HKTDC is a statutory body established in 1966 to promote, assist and develop Hong Kong's trade. With over 50 offices globally, including 13 in the Chinese Mainland, the HKTDC promotes Hong Kong as a two-way global investment and business hub. The HKTDC organises international exhibitions, conferences and business missions to create business opportunities for companies, particularly small and medium-sized enterprises (SMEs), in the mainland and international markets. The HKTDC also provides up-to-date market insights and product information via research reports and digital news channels. For more information, please visit: www.hktdc.com/aboutus. Copyright 2026 ACN Newswire via SeaPRwire.com. All rights reserved. www.acnnewswire.com

SPRINGVILLE, UT, Apr 23, 2026 - (ACN Newswire via SeaPRwire.com) - Sisel International�today announced that it has appointed Pamela Ferry as General Manager of Australia and New Zealand as the company accelerates its expansion and transitions to full market operations across the region.Ferry brings more than 20 years of experience in the global direct selling industry, with a focus on international market expansion, distributor growth, and leadership development, including experience supporting the relaunch of underperforming markets and driving renewed growth. Throughout her career, she has held leadership roles focused on building strong teams, developing field leaders, and fostering long-term organizational success. An experienced presenter, trainer, and events professional, Ferry is recognized for her ability to connect with audiences and translate strategy into practical field execution. Her strengths in relationship building and education position her to play a key role in developing Sisel's distributor network and establishing a strong foundation in the region.The appointment comes at a pivotal stage as Sisel expands into the Australian market, with a focus on building infrastructure, enabling�distributor growth, and introducing its science-driven wellness solutions to new audiences. Ferry will lead efforts to develop market operations, strengthen field support, and drive sustainable growth across Australia and New Zealand."Australia represents an important opportunity for Sisel as we continue our international expansion," said Tom Mower Jr., CEO and Co-Founder of Sisel International. "Pamela brings not only deep industry experience, but a proven ability to develop leaders and build strong distributor networks. Her leadership will be instrumental as we establish a long-term presence in the region."About Sisel International Sisel International is a global health and wellness company dedicated to developing high-quality, science-driven products designed to support healthier living. Co-founded by Tom Mower Sr. and led by CEO Tom Mower Jr., Sisel creates supplements, personal care, home care, and wellness solutions formulated without harmful or unnecessary ingredients. Guided by its founding principles, the company is committed to innovation, safety, and quality while empowering individuals to pursue health, longevity, and personal success worldwide.Media Contact:Sisel InternationalMarketing TeamEmail:�marketing@sisel.netWebsite: www.sisel.netSOURCE: Sisel International Copyright 2026 ACN Newswire via SeaPRwire.com. All rights reserved. www.acnnewswire.com

NEW YORK, Apr 23, 2026 - (ACN Newswire via SeaPRwire.com) - FastX today announces the official launch of its platform, a next-generation exchange built for professional and active traders who require institutional‑grade tools without surrendering custody or control of their assets. FastX goes live globally on 5 May, with traders able to access the platform directly at fastx.co.FastX combines deep on‑chain liquidity, multi‑asset perpetual futures markets, and an advanced copy-trading engine designed to bridge the gap between traditional finance and the decentralized digital asset ecosystem. By leveraging blockchain technology, the platform delivers low‑latency mirroring of trades across major decentralized networks worldwide—while keeping users in full control of their own wallets and risk."FastX was created by traders for traders," said Adelene, Chief Executive Officer of FastX. "We've spent our careers on Wall Street desks and in crypto markets, and we've seen the same problems repeat: opaque execution, misaligned incentives, and copytrading systems that ask users to blindly outsource decisions. FastX is our answer—a decentralised, transparent infrastructure layer where traders keep custody, and technology works to augment, not replace, their edge."Backed by a team of veteran traders with more than 50 years of combined experience across top Wall Street institutions and leading crypto trading firms, FastX is built from the ground up as a decentralised protocol. Users connect their own wallets, maintain self‑custody at all times, and interact with smart contracts that execute trades on‑chain, rather than relying on a centralised broker or custodial exchange.At launch, FastX will offer:Deep, on‑chain liquidity across a wide range of perpetual markets, designed to support serious position sizes with tight spreads and minimal slippage.A fast, intuitive trading interface accessible directly via fastx.co, allowing traders to plug in with their preferred wallet and start trading in minutes.A transparent affiliate and points system that shares a meaningful portion of platform fees with the community and rewards traders and partners who help grow liquidity and volume.The flagship feature of FastX is its next‑generation copytrading system. Unlike traditional social trading products that mirror orders on a single venue with unpredictable delays, FastX's engine is designed to route and synchronise copy trades across major decentralised exchanges, layering those capabilities on top of FastX's own liquidity.The result is a copytrading experience that aims to:Minimise latency between lead and follower execution.Mitigate structural risks such as slippage, desync, and obvious forms of manipulation.Exploit decentralised advantages, such as transparent on‑chain track records and programmable risk controls, without turning the platform into a centralised black box."Copytrading has always been typecast as a blind, autonomous disaster waiting to happen," Adelene added. "FastX takes the opposite stance. We use technology to bring more transparency, not less—on‑chain track records, built‑in risk parameters, and infrastructure that reduces front‑running and execution games wherever possible. Over time, our goal is to layer AI‑driven intelligence on top of this foundation so that users can benefit from advanced analytics and risk management, rather than just 'follow and hope'."FastX is currently seed‑funded by a network of angels deeply embedded in the global crypto trading ecosystem. These backers share a common view that the next generation of markets will be built on open, verifiable rails and that traders deserve better, more transparent instrumentation for expressing and managing risk. FastX is assembling a strong advisory board of experienced traders, market makers, and technologists to guide the exchange through its next phase of growth.As a decentralised protocol, FastX does not take custody of user funds and does not operate as a traditional broker. All positions, liquidations, and fee flows are visible on‑chain, giving traders clear, verifiable insight into how the system behaves under all market conditions."Our vision is simple," said Adelene. "We want professional‑grade perpetuals and intelligent copytrading to live where they belong: on transparent, decentralised infrastructure, not in a black box. Launching FastX on 5 May is the first step. From here, we'll continue to ship faster execution, smarter tooling, and AI‑enhanced copytrading that helps traders survive and thrive in 24/7 markets."Traders can learn more and access the exchange at https://fastx.co.About FastXFastX focuses on building decentralised financial infrastructure and tools for professional traders and sophisticated market participants. The company backs products that prioritise self‑custody, transparency, and robust risk management in rapidly evolving digital asset markets.Media ContactBrand: FastX Perpetuals ExchangeContact: Ella HuangWebsite: https://fastx.co/ Copyright 2026 ACN Newswire via SeaPRwire.com. All rights reserved. www.acnnewswire.com

Zurich, Apr 23, 2026 - (ACN Newswire via SeaPRwire.com) - Akkodis, a global leader in digital engineering consulting and part of the Adecco Group has been named a "Leader" by Information Services Group (ISG) in the ISG Provider Lens™ Digital Engineering Services 2026 reports, recognizing the company's strength across critical engineering and technology domains in Europe and the United States.Image: Akkodis named leader in ISG Digital Engineering Services 2026. Source: AkkodisAkkodis earned Leader status in the following quadrants:Augmented Design and R&D Services (Europe)Intelligent Operations and Connected Experiences (Europe)Integrated Platform and Application Services (Europe and U.S.)Leadership in augmented design & R&D servicesISG highlights Akkodis' expertise in end‑to‑end product development, including systems architecture, Model-based Systems Engineering (MBSE) integration, unified tool chains and multi‑domain engineering. The company's digital twin methodologies support deep physical-digital integration for safety‑critical products. By integrating engineering and digital toolchains, Akkodis accelerates agile product development from concept to lifecycle management across automotive, aerospace, rail and industrial sectors.ISG also recognizes Akkodis' leadership in software-defined vehicle (SDV) engineering, with capabilities spanning hardware-in-the-loop (HIL) automation, telemetry pipelines, cloud‑scale validation and AI‑supported analytics. This has been successfully showcased through the Akkodis SDV Academy where clients accelerate advanced driver‑assistance systems (ADAS) and SDV verification while addressing engineering talent gaps. Expertise in embedded systems, sensor fusion and real‑time software reinforces Akkodis' position across mobility, industrial and defense applications.Advancing intelligent operations & connected experiencesISG recognizes Akkodis for advancing industrial intelligence and transforming factory and mission-critical operations. Through smart commissioning frameworks, digital twins and advanced simulation tools, the company helps clients accelerate digital factory planning, reduce layout risks and improve overall equipment effectiveness (OEE). Akkodis also supports predictive quality and maintenance through acoustic sensing, physics-based AI and data-driven diagnostics. Its operations capabilities (including ruggedized hardware engineering, over-the-air (OTA) lifecycle management and industrial asset health solutions), have been applied across industries and asset-intensive environments requiring reliability, safety compliance, environmental resilience and long-term continuity.Strength in Integrated Platform & Application ServicesAkkodis' digital solutions advance AI‑led autonomous engineering by accelerating validation, enhancing quality and enabling compliance‑by‑design at scale. In Europe, ISG highlights Akkodis' Unified AI Platform, powered by AI-Core, alongside its deep expertise in cloud, hybrid and sovereign architectures, including AWS, Azure and sovereign deployments, which helps organizations balance agility with security, compliance and data residency requirements.In the U.S., ISG cites Akkodis' leadership in cloud‑native, MACH‑aligned modernization. Its AI‑enabled development frameworks embed intelligence into workflows, accelerating modernization and enabling personalized digital experiences. DevSecOps, compliance‑by‑design models and a secure, modular AI‑Core platform, enable Akkodis to provide scalable, cloud‑native innovation and flexible integration across modern enterprise and platform ecosystems."We are proud to receive this recognition from ISG which underscores the depth of Akkodis' global digital engineering expertise and our ability to combine AI‑driven engineering, cloud‑agnostic platforms and compliance‑by‑design at global scale to help clients innovate with Akkodis Intelligence across dynamic and complex environments," said Jo Debecker, President & CEO of Akkodis.Shirish Madhukar Kulkarni, Lead Analyst, ISG, said, "Akkodis uniquely combines deep engineering expertise with AI‑led digital twins and scalable platforms to enable faster product innovation, resilient operations, and connected, data‑driven experiences." Srinivasan P N, Senior Lead Analyst, ISG added, "Akkodis' leadership is rooted in four decades of European engineering excellence, where systems engineering, validation depth and software defined innovation converge through Akkodis Intelligence to deliver trusted, AI enabled digital engineering at scale."Media contactsAnne FriedrichSVP, Global Head of Communications, AkkodisM. +4915174633470E. anne.friedrich@adeccogroup.comLisa BushkaVP, External Communications, AkkodisM. +18604630770E. lisa.bushka@adeccogroup.comAbout AkkodisAkkodis is a global digital engineering consulting company that enables organizations to innovate and accelerate by applying technology to redefine how processes and products are developed, powered and optimized. With deep expertise across AI, data, cloud, edge and software engineering, we offer best-in-class technology consultancy. Through our strong, scalable delivery models and specialized talent, we provide end-to-end solutions, from strategy and consulting through implementation. Our commitment to Akkodis Intelligence helps businesses connect the exponential power of technology with the irreplaceable strengths of human thinking and collaboration. Part of the Adecco Group and headquartered in Switzerland, Akkodis brings together 40,000 engineers and digital experts in over 30 countries, with services that span Consulting, Solutions and Academy. With deep experience across the world's major industries, Akkodis empowers businesses to solve complex challenges and achieve sustainable impact.  akkodis.com | LinkedIn | Instagram | Facebook | XAbout the Adecco GroupThe Adecco Group is the world's leading talent company. Our purpose is making the future work for everyone. Through our three global business units - Adecco, Akkodis and LHH - across 60 countries, we enable sustainable and lifelong employability for individuals, deliver digital and engineering solutions to power transformation and empower organisations to optimise their workforces. The Adecco Group leads by example and is committed to an inclusive culture, fostering sustainable employability, and supporting resilient economies and communities. The Adecco Group AG is headquartered in Zurich, Switzerland (ISIN: CH0012138605) and listed on the SIX Swiss Exchange (ADEN). www.adeccogroup.comAbout ISGISG (Information Services Group) is a leading global technology research and advisory firm. A trusted business partner to more than 900 clients, including more than 75 of the world's top 100 enterprises, ISG is committed to helping corporations, public sector organizations, and service and technology providers achieve operational excellence and faster growth. The firm specializes in digital transformation services, including automation, cloud and data analytics; sourcing advisory; managed governance and risk services; network carrier services; strategy and operations design; change management; market intelligence and technology research and analysis. Founded in 2006, and based in Stamford, Conn., ISG employs more than 1,600 digital-ready professionals operating in more than 20 countries-a global team known for its innovative thinking, market influence, deep industry and technology expertise, and world-class research and analytical capabilities based on the industry's most comprehensive marketplace data. For more information, visit www.isg-one.com.SOURCE: Akkodis Copyright 2026 ACN Newswire via SeaPRwire.com. All rights reserved. www.acnnewswire.com

香港, 2026年4月23日 - (亞太商訊 via SeaPRwire.com) - 全球ADC藥物市場正經歷爆發式增長，2024年市場規模突破250億美元，其中前五大商業化產品的年度銷售額均突破10億美元，Padcev更是以近26億美元的成績證明了靶向Nectin-4 ADC的廣闊前景。與此同時，中國創新藥企不再滿足於本土市場，紛紛將目光投向海外。在這一輪出海浪潮中，邁威生物憑藉差異化的管線設計、積極的對外授權策略以及新興市場的商業化落地，逐步展現出清晰的全球化路徑。邁威生物成立於2017年，是一家具備從藥物發現到商業化銷售全產業鏈能力的中國創新製藥公司。公司已於2022年1月在上海證券交易所科創板上市（股票代碼：688062），此次赴港上市旨在構建「A+H」雙融資平臺，進一步打開國際資本通道，為海外商業化創造更便利的條件。核心產品獲FDA多項認定，國內外臨床試驗啟動截至目前，邁威生物擁有4款已上市產品及10款候選藥物，覆蓋腫瘤、免疫、骨科、眼科等領域。其中，核心產品9MW2821（靶向Nectin-4 ADC）在多個適應症上展現出全球領先的臨床開發進度。在尿路上皮癌領域，該產品是在中國開發的同類靶點ADC中進展最快的，全球範圍內僅次於已上市的Padcev；其聯合特瑞普利單抗的一線療法III期試驗正在推進中，有望於2027年提交新藥上市申請（NDA）。在宮頸癌領域，9MW2821更是全球首款進入關鍵III期試驗階段的靶向Nectin-4 ADC，該III期臨床試驗已於2024年9月啟動，預計2027年完成。針對三陰性乳腺癌，9MW2821精准聚焦拓撲異構酶抑制劑ADC經治後的耐藥患者這一差異化賽道，已在中國開展II期試驗，並於2025年8月在美國啟動I期研究，計畫後續開展全球多中心II期或III期臨床試驗。目前，9MW2821已累計獲得美國FDA授予的多項快速通道認定及孤兒藥資格認定，並獲中國國家藥監局授予兩項突破性療法認定，充分驗證了其全球同類最佳的潛力。除核心產品9MW2821外，邁威生物的ADC管線儲備同樣頗具看點。靶向B7-H3的7MW3711已在國內獲批聯合特瑞普利單抗及JS207等療法的Ib/II期研究，並獲FDA授予小細胞肺癌孤兒藥資格，初步臨床資料在肺癌、食管癌等實體瘤中顯示出良好安全性與抗腫瘤活性。另一款靶向CDH17的7MW4911則在中美雙軌並行，國內I期與美國I/II期臨床同步推進，精准聚焦高發消化道腫瘤。兩款產品的快速推進不僅豐富了公司ADC產品矩陣，更凸顯了其在差異化靶點佈局與全球臨床開發上的創新執行力。超20億美元對外授權，驗證管線全球價值通過對外授權將早期管線的價值變現，同時加速已上市產品的商業化放量，邁威生物已形成清晰的商業閉環。2025年，公司總收入達到6.59億元人民幣，同比增長230.0%。其中對外授權收入4.09億元，收入占比62%。主要授權合作包括：授予齊魯製藥在大中華區獨家開發及商業化邁粒生®（長效G-CSF）的權利，獲得首付款及里程碑付款；授予Disc在除大中華區及東南亞以外的全球範圍內獨家許可9MW3011（抗TMPRSS6單抗）的權利，潛在里程碑金額最高達4.125億美元，並已達成II期試驗里程碑；授予Calico在除大中華區以外的全球獨家開發及商業化9MW3811（靶向IL-11單抗）的權利，潛在里程碑金額最高近6億美元；授予Kalexo Bio在全球範圍獨家開發、生產和商業化雙靶點siRNA候選藥物的權利，潛在里程碑金額最高可達10億美元，此外公司還有權獲得其雙位數A輪優先股股權。上述合作總潛在里程碑金額超過20億美元，不僅為公司帶來了即期現金流入，也證明了其創新管線的國際競爭力。通過精准選擇深耕細分領域的合作夥伴並實施對外授權，公司已將創新管線的價值推向全球舞臺；與此同時，依託自主研發夯實長期創新根基，邁威生物在早期價值變現與持續研發投入之間建立起良性迴圈，實現了全球化佈局與內生增長的雙重驅動，構建起可持續的創新發展範式。生物類似藥持續落地，商業化網路持續擴張在產品出海方面，邁威生物以生物類似藥作為切入新興市場的突破口。2025年8月，邁利舒®及邁衛健®在巴基斯坦獲批上市，成為巴基斯坦首個獲批的Prolia®及Xgeva®生物類似藥。此外，公司已與巴西、秘魯、沙特阿拉伯、菲律賓等多個國家的領先製藥公司簽訂合作協定，推動產品在當地的註冊與商業化。2025年12月，君邁康®（阿達木單抗生物類似藥）也在印尼獲批上市，並已與16個國家訂立海外合作協定。同時，公司自主研發的長效G-CSF邁粒生®於2025年5月獲批上市，是首個全球上市的採用白蛋白長效融合技術開發的G-CSF藥物，公司已將其在大中華區的獨家開發及商業化權利授予齊魯製藥。依託齊魯製藥在腫瘤領域成熟的銷售網路和強大的商業化能力，邁粒生®有望快速切入龐大的G-CSF市場，有效解決該領域大量未得到滿足的醫療需求，在競爭激烈的市場中佔據一席之地。這些海外上市進展表明，邁威生物不僅具備研發能力，更擁有將產品推向國際市場的註冊與商業化執行力。對於新興市場而言，高品質且具成本優勢的生物類似藥存在巨大未滿足需求，邁威生物的提前佈局有望在未來數年持續貢獻收入增量。為支撐海外商業化佈局，邁威生物始終堅持以國際標準構建品質體系。公司位於江蘇泰州的生產基地嚴格符合中國GMP標準及歐盟EMA GMP標準，而正在建設的上海金山大規模商業化生產基地同樣遵循歐盟EMA GMP標準設計。此外，公司的地舒單抗生產線已零缺陷通過哥倫比亞INVIMA的現場審計。基於此，邁衛健®（地舒單抗，120mg）和邁利舒®（地舒單抗，60mg）已成功實現海外商業化發貨。接軌國際的品質管制體系不僅為產品在新興市場的註冊與商業化奠定了堅實基礎，也確保了公司在全球供應鏈中的合規性與競爭力。結語邁威生物已構建起涵蓋差異化ADC管線、對外授權落地、生物類似藥海外上市及國際品質體系認證的全球化佈局，實現了自主研發、對外授權與海外商業化的協同驅動。此次赴港上市不僅是其資本戰略的關鍵一步，更將為其打開國際資本通道，加速海外臨床研究、全球註冊申報以及商業化網路拓展。在港股生物醫藥板塊估值處於歷史低位的當下，公司用扎實的管線與商業化成果，向國際投資者展示了中國創新藥的務實路徑。具備真正全球化能力的ADC新貴，值得長期關注。 Copyright 2026 亞太商訊 via SeaPRwire.com. All rights reserved. www.acnnewswire.com

SINGAPORE, Apr 23, 2026 - (ACN Newswire via SeaPRwire.com) - Sinch Mailgun, part of Sinch, has released its Email Impact Report 2026, introducing new industry benchmarks across 10 high-volume sending sectors and revealing a gap between email performance and execution.Based on insights from more than 400 billion emails sent in 2025 and a global survey of over 1,200 email senders, the report shows that while email remains a critical, high-performing channel, poor deliverability is leaving significant revenue on the table. Nearly 18% of emails fail to reach the inbox, putting up to a fifth of potential return on investment at risk for many organisations.78% of respondents say email is critical to business success. At the same time, the research highlights a growing disconnect between performance and execution, driven by gaps in measurement, deliverability practices and AI application.“APAC businesses rely heavily on email to drive sales, loyalty and customer experience but many are not set up to capture its full value,” said Ginger Kidd, Vice President Marketing & Communications APAC at Sinch. “What we see in this data reflects what’s happening locally: brands are investing in email and seeing strong returns, yet there is still a high number of messages that never reach inboxes. For instance, in a market as competitive and cost-conscious as Australia, marketers simply can’t afford for emails to get lost in inboxes. When budgets are under pressure, fixing deliverability is one of the fastest ways to unlock more value from the spend they already have.”AI adoption is widespread, but its impact remains uneven. Many teams focus on basic use cases such as content generation, while higher-impact applications such as optimisation, segmentation and deliverability remain underutilised. Organisations that use AI more effectively are significantly more likely to report improved email performance.Ginger Kidd said: "Across the diverse markets of APAC, we’re seeing a common theme: marketers are enthusiastically adopting AI, but the initial focus has primarily been on content creation. The true opportunity now lies in leveraging AI for smarter decision-making. For instance, who to send to, how often, and with what level of risk. This strategic shift is the key to ensuring every campaign improves performance, not just adds volume.“The most sophisticated teams are already using AI to predict which subscribers are at risk of disengaging, to fine-tune send times and to protect sender reputation. That’s where we’re seeing a real uplift in performance, not just faster content production.”Key findings of the report include:60% of companies measuring email ROI report returns above $10 for every $1 spentMore than 1 in 10 achieve returns as high as 40:146% say AI improves speed and efficiency41% of teams use AI to generate email content23% say AI has not improved their email programs49% report improved email performance year-over-year79% plan to maintain or increase investment in emailFewer than half of organisations can confidently measure email ROIAbout the reportThe Email Impact Report 2026 combines:Data from 400+ billion emails sent in 2025Insights from 1,200+ email senders globallyBenchmarks across 10 high-volume industriesRead more about the report here.About SinchSinch’s vision is to connect every business with every customer, everywhere in the world. With the industry’s most trusted foundation for intelligent customer communications, Sinch powers over 900 billion customer interactions annually for more than 200,000 customers across the globe. Leading global companies, including AI innovators, rely on Sinch to strengthen customer relationships and deliver seamless experiences across messaging, email and voice. Profitable since its founding in 2008, Sinch generated net sales of USD 3 billion (SEK 27 billion) in 2025 and has over 4,000 Sinchers in 60 countries, with headquarters in Stockholm. Sinch is listed on Nasdaq Stockholm (XSTO: SINCH). Visit us at sinch.com.About Sinch MailgunSinch Mailgun is the email infrastructure platform built for developers and businesses that demand reliable, high-performance delivery at scale. Trusted by companies worldwide, Mailgun powers transactional, marketing, and programmatic email through a developer-first API, advanced deliverability tools, and real-time analytics. As part of Sinch — the industry’s most trusted foundation for intelligent customer communications — Mailgun connects businesses to their customers through every send, at every scale. Visit us at mailgun.com.For more information, please contact:Tracey ChooCommunications Manager, APAC at SinchE-mail: tracey.choo@sinch.com Copyright 2026 ACN Newswire via SeaPRwire.com. All rights reserved. www.acnnewswire.com