Everest Medicines Enters into Asset Purchase Agreement for Etripamil Nasal Spray, Expanding Cardiovascular Footprint

HONG KONG, March 23, 2026 - (ACN Newswire via SeaPRwire.com) - Everest Medicines today announced that it has entered into an Asset Purchase Agreement with Corxel Pharmaceuticals Hong Kong Limited ("CORXEL"). Under the agreement, the Company has acquired the rights to develop, manufacture, and commercialize CARDAMYST™ (etripamil) nasal spray in Greater China, including Chinese Mainland, Hong Kong, Macao and Taiwan region.Under the terms of the agreement, Everest will pay CORXEL an upfront payment of US$30 million (equivalent to approximately RMB344,895,000), as well as potential development milestone payments of up to US$20 million (equivalent to approximately RMB137,958,000). As part of this agreement, Everest will be assigned and transferred rights, interests, claims, duties, obligations and liabilities (other than certain excluded liabilities) under the Milestone License Agreement entered into by CORXEL in May 2021 and certain related ancillary agreements.CARDAMYST™ (etripamil) nasal spray is a novel, rapid-acting calcium channel blocker as administered as needed via a convenient, portable nasal spray. It offers rapid onset of action, favorable tolerability, and the potential for at-home self-administration, enhancing patient accessibility. In December 2025, CARDAMYST was approved by the U.S. Food and Drug Administration (FDA), becoming the first and only self-administered nasal spray in more than 30 years capable of converting paroxysmal supraventricular tachycardia (PSVT) to sinus rhythm in adults. As a rapid-acting treatment option, CARDAMYST can be self-administered outside the emergency department or other healthcare settings, enabling patients to actively manage episodes and gain greater control over their condition. In addition to its approved indication for PSVT, etripamil nasal spray is also under clinical development for atrial fibrillation with rapid ventricular response (AFib-RVR). Phase II trials have shown encouraging results, and Phase III trials are planned, with the potential to further extend its therapeutic impact to a broader patient population.In China, the New Drug Application (NDA) for etripamil nasal spray was accepted by the National Medical Products Administration (NMPA) on January 17, 2025 and is expected to receive approval in the third quarter of 2026.PSVT is characterized by abnormalities in the heart's electrical system that cause sudden unexpected and often severely symptomatic episodes of rapid heart rate. There are currently no approved self-administered, fast-acting, non-injectable therapies for acute PSVT, leaving patients with limited treatment options beyond emergency care. Approximately 2.3 to 4 per 1,000 individuals are affected by PSVT, representing an estimated 3 to 6 million patients in China.AFib-RVR is a type of irregular heart rhythm, characterized by an irregular and elevated heart rate. Its onset is typically gradual, episodes are less likely to terminate spontaneously, and the condition tends to recur, significantly increasing the risk of thromboembolism and serious complications such as stroke and heart failure. In China, atrial fibrillation affects an estimated 1.6% of the population, representing nearly 20 million patients, and is expected to increase with an aging population. Both PSVT and AFib-RVR are associated with a loss of control and a significant psychological burden for patients.Overall, the combined patient population for PSVT and AFib-RVR exceeds 25 million, representing a significantly unmet clinical need that urgently requires more convenient and more effective treatment options.In terms of clinical data, the NDA for etripamil nasal spray was accepted by the NMPA based on data from the pivotal global Phase 3 RAPID study and the China Phase 3 JX02002 study. Both trials met their primary endpoints. Overall, the treatment emergent adverse events (TEAEs) were comparable between the etripamil and placebo groups. The FDA approval of CARDAMYST was supported by a robust clinical program that included safety data from more than 1,800 participants across more than 2,000 PSVT episodes. This included the Phase 3 RAPID trial, a global, randomized, double-blind comparison of etripamil versus placebo, published in The Lancet in 2023. The RAPID trial achieved its primary endpoint, with 64% of participants who self-administered etripamil (N=99) converting from supraventricular tachycardia (SVT) to sinus rhythm within 30 minutes compared with 31% on placebo (N=85) (HR = 2.62; p<0.001). The median time to conversion was 17 minutes (95% CI: 13.4, 26.5) for etripamil versus 54 minutes (95% CI: 38.7, 87.3) for placebo. Etripamil nasal spray is also under clinical development for AFib-RVR. In the randomized, controlled Phase-2 ReVeRA study, etripamil demonstrated rapid and significant reduction in ventricular rate in patients with AFib-RVR, achieving its primary endpoint. A greater number of patients receiving etripamil achieved a ventricular rate of less than 100 bpm (58.3%) than those receiving placebo (4%). The safety profile was consistent with previous studies.From a strategic perspective, this transaction is also seen as an important step for the Company in implementing 2030 Strategy. Driven by its 2030 Strategy, and led by Mr. Yifang Wu, Chairman of the Board, Everest is accelerating growth through a dual-engine approach that combines strategic business development partnerships with in-house R&D. This transaction further strengthens Everest's expanding cardiovascular franchise, building on recent strategic initiatives and reinforcing the Company's disciplined approach to constructing focused therapeutic verticals with meaningful lifecycle expansion potential. Through continued advancement of its pipeline and product portfolio globally, Everest aims to deliver innovative therapies to more patients, create sustainable long-term value, and advance its position to become a leading global biopharmaceutical company."We are pleased to collaborate with CORXEL, this agreement marks an important step in our continued expansion in the cardiovascular field and a meaningful milestone in advancing our growth 2030 strategy," said Mr. Rogers Yongqing Luo, Chief Executive Officer of Everest Medicines. "CARDAMYST is currently the only therapy designed for at-home self-administration to enable the acute termination of PSVT and AFib-RVR episodes, addressing a significant unmet medical need among patients in China. We will leverage our clinical development expertise and established commercialization platform to accelerate its advancement and future launch in Greater China, while further strengthening our cardiovascular franchise and unlocking its broader potential across atrial arrhythmias."As the registration and commercialization of Etripamil nasal spray progress, the company aims to further expand its cardiovascular portfolio. Leveraging its established clinical development and commercialization capabilities, Everest Medicines will accelerate the delivery of innovative assets, advance its 2030 strategy, and bring more treatment options to patients. Copyright 2026 ACN Newswire via SeaPRwire.com. All rights reserved. www.acnnewswire.com

Xunce Technology’s Revenue Surges 449% Half-on-Half: Is a Structural Revaluation to a Hundred-Billion Market Cap Camp on the Horizon?

HONG KONG, Mar 27, 2026 - (ACN Newswire via SeaPRwire.com) - As AI accelerates into the inference era, enterprise-grade AI is achieving large-scale deployment, driving an exponential surge in Token consumption and ushering data demand into a new development stage. Against this backdrop, high-quality, structured and scenario-specific professional data has become critical for enterprises to forge core strategic competitiveness in the era of AI.As a leading provider of AI real-time data infrastructure and analysis services in China, Xunce Technology is rapidly solidifying its core position in AI data, driven by industry tailwinds, full-chain technological capabilities and diversified growth engines. Amid the unfolding landscape of the intelligent economy, this ten-year industry stalwart is entering a pivotal window for structural revaluation.Token Value Restructuring: Making Every Data Access Quantifiable and MonetizableFounded in 2016, Xunce Technology has built a full-chain technological system spanning data acquisition, cleansing, standardization, real-time computing and large- model optimization over a decade of development. With AI Data Agent at its core, the Company specializes in millisecond-level real-time data processing, serving a diversified portfolio of industries including finance, urban governance, high-end manufacturing, healthcare, robotics, satellite applications, low-altitude economy, electric power, power grids and energy.As the era of AI inference unfolds, Token is evolving from mere “fuel” to a form of “hard currency”. Maximizing the value of each individual Token has emerged as a central challenge in the large-model inference era. Today, general-purpose large models typically rely on a “computing power for precision” approach, where every inference run generates substantial wasteful Token consumption. Should inference fail, all Tokens expended in the process are lost entirely, which is a common pain-point plaguing general AI systems.By contrast, vertical AI solutions equip general large language models with an external industry “brain” powered by domain-specific data. At its core, such solutions optimize inference logic via business-aware models, enabling upfront task feasibility validation and eliminating Token waste at the source. With deep expertise in professional vertical domain data modeling, Xunce Technology leverages its extensive portfolio of high-quality, scenario-specific proprietary data to act as an “efficiency multiplier” for every Token invocation. This structure translates Token consumption into higher-precision outputs while securing maximal result certainty. Crucially, the Company is developing full-chain capabilities spanning data metering, pricing and settlement, enabling quantifiable and monetizable measurement for every data access. By elevating per-unit Token efficiency, it delivers enhanced business value to enterprise clients.Aligned with this strategy, Xunce’s platform features a “LEGO-inspired” modular architecture, enabling clients to flexibly compose modules tailored to their specific needs. This “assemble-on-demand, adapt-in-real-time” design fosters deep and long-term customer stickiness. The Company also employs a highly flexible pricing framework, with fees structured around module count, processing throughput and other key metrics. Supported by subscription, transaction-based and Token-based payment models, its pricing mechanism precisely aligns with diverse client demands.Currently, Xunce Technology is fully building a full-chain data measurement and settlement system. It is exploring pricing mechanisms tied to large model inference frequency and module usage count, allowing customers to pay for effective Tokens rather than raw computing power consumption.Inflection Point Reached, Profitability ConfirmedDriven by Token value restructuring and innovative business models, Xunce Technology has delivered robust performance and reached a historic inflection point. In H2 2025, the Company posted an adjusted net profit of RMB 50 million, achieving its first positive profitability. Meanwhile, revenue rose from RMB 197.85 million in H1 2025 to RMB 1,086.81 million in H2, representing a 449.32% quarter-on-quarter surge. Amid rapid business expansion, the Company has witnessed a substantial improvement in profitability.Explosive Revenue GrowthReturn to Profit in H2Doubled ARPU & Per Capita GrowthImproved Cash Flow & Operating Metrics+103% Y/YNarrowed by 33%+105% Y/YSignificant Improvement2025 full-year revenue YoY growth2025 full-year adjusted net loss2025 ARPU YoY growth2025 net operating cash flow+449% H/HRMB 50 million+135% Y/YAmple cash on hand in 20252025 H2 revenue HoH growth2025 H2 adjusted net profit2025 per capita revenue YoY growthAverage collection period decreased in 2025For the full year, the Company posted total operating revenue of RMB 1,284.66 million, representing a substantial year-on-year increase of 103.28% and successfully breaking the key milestone of RMB 1 billion in revenue. This signifies that the Company has evolved from an early-stage, technology-driven startup into a new era of platform-based development with scalable and replicable business models.Furthermore, the Company’s combined gross proceeds for 2025 amounted to approximately RMB 792.08 million, representing a substantial increase of 63.44% compared to approximately RMB  484.63 million in the previous year. In terms of adjusted net loss, after deducting one-off non-recurring gains and losses, the Company’s adjusted net loss for 2025 was RMB 54.84 million, representing a significant narrowing of 33% from RMB 82.37 million in 2024.Notably, the Company achieved combined gross margin of 62% in 2025, exceeding that of Cambricon (55%), a leading AI chip provider, and far outpacing general large- model developer Minimax (25.4%). This underscores its high-value strategic positioning and resilient business model in the AI data infrastructure sector.In terms of R&D investment, Xunce Technology has also maintained efficient growth conversion. In 2025, the Company’s R&D expenditure reached RMB 450.44 million, with R&D expenses accounting for 48% of revenue, driving a 105% year-on-year increase in operating revenue. For comparison, Minimax’s R&D expenditure accounted for as high as 219% of its revenue, with a revenue growth rate of 159%. Xunce achieved a comparable expansion pace with a lower R&D intensity.As revenue scale continues to expand and gross margin in new industries gradually stabilize, the Company’s short-term objective is to achieve an inflection point in adjusted net profit. Looking ahead, as the industries already deployed enter a period of margin stabilization and Token-based payment and revenue-sharing models gain accelerated traction, its net profit is poised to improve at an accelerated rate.Driven by Diversified Growth Engines, Business Structure Continuously OptimizedThe robust revenue growth is not accidental, but underpinned by Xunce Technology’s multi-dimensional, systematically structured growth framework.Accelerate cross-industry replication. The Company currently covers 9 major industries, benchmarking Palantir’s 17 industries and leaving ample room for horizontal expansion. Xunce Technology is rapidly deepening its presence in key national strategic sectors such as asset management, telecommunications, electric power, urban management, high-end manufacturing, healthcare, energy, robotics training platforms and commercial aerospace. For each new industry, the Company first completes industry-specific data accumulation over 3 to 5 years, enabling rapid replication and scaled deployment across peer customers thereafter.The business model fosters deep customer value enhancement. As customers evolve from single-module adoption to multi-module deployment, and from pilot trials to full integration into core business workflows, substantial upside potential in ARPU remains. By synergistically lifting Token invocation volume, module usage count and per-Token value, the Company will unlock a new dimension of growth.Steadily expand overseas business and establish a global layout. The Company targets raising its overseas revenue share to 10% to 15% in 2026, and will further escalate its globalization strategy during 2027 and 2028, unlocking new avenues for sustained long-term growth.Cultivate a strategic cooperative ecosystem to forge deep integration with upstream and downstream partners in computing power and algorithms. Xunce Technology is engaging in in-depth collaboration with leading domestic GPU providers and large language model enterprises to build a one-stop solution encompassing “infrastructure computing power, upper-layer applications and data governance,” further solidifying its core position in the AI data infrastructure sector.      Pioneer cutting-edge applications to seize commanding heights in future industries. From robotics data platforms to commercial aerospace, low-altitude economy and power grid systems, Xunce Technology has taken the lead in extending AI infrastructure to emerging sectors with stringent demands for real-time performance and operational reliability. Such mission-critical scenarios with ultra-high requirements for data timeliness and stability serve as a rigorous validation of the Company’s technological advantages. The Company will continue to ramp up R&D investment in frontier fields, refine its technical capabilities through high-end application scenarios and unlock new high-growth, high-value growth tracks for long-term development.Evolving from Data Services to Core AI Economy Infrastructure: Building Sustainable Competitive BarriersFrom a macro perspective, the artificial intelligence data sector is witnessing a profound convergence of five defining trends: a surge in demand for real-time, secure, high-quality data in the era of AI Agent; the rise of domain-specific models elevating professional data as a critical enabler for industry-wide intelligent upgrading; standardization of data interfaces driven by next-generation AI operating systems including Open Claw, positioning Xunce Technology as a core data Token provider; Token-based payment emerging as a new paradigm for the data element market; and the implementation of data asset capitalization policies, spurring a sharp rise in enterprises’ mandatory investment in data governance.At the intersection of these five pivotal trends, Xunce Technology has established a robust fundamental logic for sustained long-term growth. The Company has evolved beyond a traditional data infrastructure provider to become a critical “connector” and “enabler” linking large models, computing power and cloud vendors. By integrating upstream models, downstream computing power and horizontal collaboration with cloud vendors, the Company delivers irreplaceable data-centric value to its enterprise clients.The Company stresses that it shares a natural upstream-downstream synergy with general large-model providers, rather than a competitive dynamic. Analogous to the deep collaboration between GPU manufacturers and model developers, the value of Xunce Technology lies in a mutually reinforcing cycle: the wider the adoption of models by its clients, the greater the opportunity for the Company to deliver services and generate incremental value for clients.Notably, in contrast to niche market players offering only isolated modules such as data cleansing or computing engines, Xunce Technology’s core differentiation lies in its full-process coverage and outcome-driven accountability. The Company provides an end-to-end solution spanning data acquisition, cleansing, standardization, modeling, real-time computing and model tuning, ensuring that final data delivered to clients is clean, accurate, real-time and accessible for model invocation at millisecond latency. Furthermore, through deep integration into clients’ private clouds or on-premises environments, the Company acts as a dedicated data steward, fostering exceptional customer stickiness and forging robust, sustainable competitive barriers.Currently, the Company’s product portfolio and solutions feature more than 300 functional modules, covering a full spectrum of scenarios from data infrastructure to upper-layer analytics applications. In 2025, its active paid clients base reached 230, with an outstanding customer retention rate of 90%. ARPU increased substantially from RMB 2.72 million in 2024 to RMB 5.59 million in 2025, representing a year-on-year growth of over 103%.As algorithms become increasingly open-source and computing power tends toward standardization, what truly sets companies apart lies in data — particularly industry data that has undergone sophisticated governance and can effectively empower large models. Backed by a decade of deep industry expertise, Xunce Technology has established a substantial and sustainable competitive barrier in this domain.ConclusionFrom an early-stage private equity tool provider to a cross-industry AI data infrastructure builder, and from a module supplier to a Token-priced core platform, Xunce Technology has remained committed to unlocking data as a scarce, strategic resource that is freely circulable, readily callable and empowered to drive high-quality decision-making.Amid the rapid emergence of new intelligent economic paradigms, the Company stands at the threshold of a fundamental structural revaluation, with the potential to enter the RMB 100-billion market cap camp. It is a competitor to none, but an indispensable partner to all. Copyright 2026 ACN Newswire via SeaPRwire.com. All rights reserved. www.acnnewswire.com

Application Submitted for LENVIMA(R) (lenvatinib) in Japan Seeking Approval of Additional Dosage and Administration for Combination with WELIREG(R) (belzutifan) for Renal Cell Carcinoma that has Progressed After Chemotherapy

TOKYO, Mar 27, 2026 - (JCN Newswire via SeaPRwire.com) - Eisai Co., Ltd. (Headquarters: Tokyo, CEO: Haruo Naito, “Eisai”) and MSD K.K. (Headquarters: Tokyo, Representative Director: Prashant Nikam, “MSD”), a subsidiary of Merck & Co., Inc., Rahway, NJ, USA, announced today that an application for LENVIMA® (lenvatinib), an orally available multiple receptor tyrosine kinase inhibitor (TKI) discovered by Eisai, has been submitted in Japan for the additional dosage and administration in combination with WELIREG® (belzutifan), the first-in-class oral hypoxiainducible factor-2 alpha (HIF-2α) inhibitor from MSD, for the treatment of unresectable or metastatic renal cell carcinoma that has progressed after chemotherapy.This application is based on the results of the Phase 3 LITESPARK-011 trial evaluating the dual regimen of LENVIMA plus WELIREG for the treatment of patients with advanced renal cell carcinoma (RCC) whose disease progressed on or after treatment with anti-programmed death receptor-1 (PD-1)/ programmed death-ligand 1 (PD-L1) therapy. The data from this trial were presented at the 2026 American Society of Clinical Oncology (ASCO) Genitourinary (GU) Cancers Symposium in February 2026. At a pre-specified interim analysis with a median follow-up of 29.0 months (range, 19.3-49.2), the LENVIMA plus WELIREG combination therapy demonstrated a statistically significant and clinically meaningful improvement in progression-free survival (PFS), one of the primary endpoints, reducing the risk of disease progression or death by 30% (HR=0.70 [95% CI, 0.59-0.84]; p=0.00007) compared to cabozantinib. The safety profile of this combination was consistent with those reported for each agent administered as monotherapy, and no new safety signals were identified.In 2022, approximately 435,000 people worldwide were newly diagnosed with kidney cancer, and about 156,000 people died from the disease. 1 In Japan, it is estimated that roughly 21,000 people were newly diagnosed and about 7,000 died in 2022.2 RCC accounts for approximately 85% of kidney cancers3, and the five-year survival rates for patients with stage III and IV RCC have been reported as 63%–78% and 27%–28%4, respectively, indicating that the disease still has a high unmet medical needs.LENVIMA is approved in combination with KEYTRUDA ® (pembrolizumab) in Japan for the first-line treatment of unresectable or metastatic RCC. WELIREG is approved in Japan for the treatment of unresectable or metastatic RCC that has progressed following cancer chemotherapy. Additionally, supplemental New Drug Applications (sNDA) for the LENVIMA and WELIREG combination therapy for the treatment of adult patients with advanced RCC with a clear cell component following a PD-1 or PDL1 inhibitor has been accepted by the U.S. Food and Drug Administration (FDA), with a PDUFA (Prescription Drug User Fee Act) target action date set for October 4, 2026.Eisai and MSD have been collaborating through the provision of information on LENVIMA in Japan since October 2018, and will work together to expedite the maximization of contribution to patients with cancer.About LENVIMA (lenvatinib)LENVIMA, discovered and developed by Eisai, is an orally available multiple receptor tyrosine kinase inhibitor that inhibits the kinase activities of vascular endothelial growth factor (VEGF) receptors VEGFR1 (FLT1), VEGFR2 (KDR), and VEGFR3 (FLT4). LENVIMA inhibits other kinases that have been implicated in pathogenic angiogenesis, tumor growth, and cancer progression in addition to their normal cellular functions, including fibroblast growth factor (FGF) receptors FGFR1- 4, the platelet derived growth factor receptor alpha (PDGFRα), KIT, and RET. In syngeneic mouse tumor models, LENVIMA decreased tumor-associated macrophages, increased activated cytotoxic T cells, and demonstrated greater antitumor activity in combination with an anti-PD-1 monoclonal antibody compared to either treatment alone. LENVIMA has been approved for the indications below.Thyroid cancer- Indication as monotherapy(Approved mainly in Japan, the United States, Europe, China and Asia)Japan: Unresectable thyroid cancerThe United States: The treatment of patients with locally recurrent or metastatic, progressive, radioiodine-refractory differentiated thyroid cancer (DTC)Europe: The treatment of adult patients with progressive, locally advanced or metastatic, differentiated (papillary/follicular/Hürthle cell) thyroid carcinoma (DTC), refractory to radioactive iodine (RAI)Hepatocellular carcinoma- Indication as monotherapy(Approved mainly in Japan, the United States, Europe, China and Asia)Japan: Unresectable hepatocellular carcinomaThe United States: The first-line treatment of patients with unresectable hepatocellular carcinoma (HCC)Europe: The treatment of adult patients with advanced or unresectable hepatocellular carcinoma (HCC) who have received no prior systemic therapy- Indication in combination with KEYTRUDA (generic name: pembrolizumab) and transarterial chemoembolization (Approved in China)Thymic carcinoma- Indication as monotherapy (Approved in Japan)Japan: Unresectable thymic carcinomaRenal cell carcinoma (In Europe other than the United Kingdom, the agent was launched under the brand name Kisplyx®)- Indication in combination with everolimus(Approved mainly in the United States, Europe and Asia) The United States: The treatment of adult patients with advanced renal cell carcinoma (RCC) following one prior anti-angiogenic therapyEurope: The treatment of adult patients with advanced renal cell carcinoma following one prior vascular endothelial growth factor (VEGF) targeted therapy- Indication in combination with KEYTRUDA(Approved mainly in Japan, the United States, Europe and Asia)Japan: Radically unresectable or metastatic renal cell carcinomaThe United States: The first-line treatment of adult patients with advanced renal cell carcinomaEurope: The first-line treatment of adult patients with advanced renal cell carcinomaEndometrial carcinoma- Indication in combination with KEYTRUDA(Approved mainly in Japan, the United States, Europe and Asia)Japan: Unresectable, advanced or recurrent endometrial carcinoma that progressed after cancer chemotherapyThe United States: The treatment of patients with advanced endometrial carcinoma that is pMMR or not microsatellite instability-high (MSI-H), as determined by an FDA-approved test, who have disease progression following prior systemic therapy in any setting and are not candidates for curative surgery or radiationEurope: The treatment of adult patients with advanced or recurrent endometrial carcinoma (EC) who have disease progression on or following prior treatment with a platinum-containing therapy in any setting and are not candidates for curative surgery.About WELIREG (belzutifan)WELIREG, Merck & Co., Inc., Rahway, NJ, USA’s, known as MSD outside of the United States and Canada, first-in-class hypoxia-inducible factor 2 alpha (HIF-2α) inhibitor, is an orally administered small-molecule designed to reduce transcription and expression of HIF-2α target genes associated with cellular proliferation, angiogenesis and tumor growth. By inhibiting HIF-2α signaling, WELIREG aims to disrupt key pathways certain tumors may use to adapt to low-oxygen conditions, including those that help promote abnormal blood vessel formation and support tumor survival. WELIREG has demonstrated antitumor activity in certain von Hippel-Lindau (VHL) diseaseassociated tumors, renal cell carcinoma and in pheochromocytoma or paraganglioma. As part of a broader clinical program, Merck & Co., Inc., Rahway, NJ, USA continues to research WELIREG monotherapy and combination approaches for people with genitourinary, breast and gynecologic cancers across a range of treatment settings to further define where HIF-2α inhibition may provide clinical benefit and to better understand which patients are most likely to respond. WELIREG has been approved in Japan for the treatment of certain von Hippel–Lindau (VHL) disease–associated tumors, as well as for unresectable or metastatic renal cell carcinoma that has progressed after chemotherapy.LITESPARK-011 ResultsData from LITESPARK-011 (ClinicalTrials.gov, NCT04586231) were presented at the ASCO GU Symposium held in February 2026. LITESPARK-011 is a randomized, open-label Phase 3 trial (ClinicalTrials.gov, NCT04586231) evaluating WELIREG in combination with LENVIMA compared to cabozantinib for the treatment of patients with advanced clear cell RCC that has progressed on or after anti-PD-1/L1 therapy. The dual primary endpoints are progression-free survival (PFS) per Response Evaluation Criteria in Solid Tumors version 1.1 (RECIST v1.1) as assessed by blinded independent central review (BICR), and overall survival (OS). Secondary endpoints include objective response rate (ORR) per RECIST v1.1 as assessed by BICR, duration of response (DOR) per RECIST v1.1 as assessed by BICR, and safety. The trial enrolled 747 patients who were randomized to receive WELIREG (120 mg orally once daily) plus LENVIMA (20 mg orally once daily) or cabozantinib (60 mg orally once daily).At a pre-specified second interim analysis with a median follow-up of 29.0 months (range, 19.3- 49.2), WELIREG plus LENVIMA demonstrated a statistically significant and clinically meaningful improvement in the primary endpoint of PFS, reducing the risk of disease progression or death by 30% (HR=0.70 [95% CI, 0.59-0.84]; p=0.00007) compared to cabozantinib. For WELIREG plus LENVIMA, the median PFS was 14.8 months (95% CI, 11.2-16.6) versus 10.7 months (95% CI, 9.2-11.1) for cabozantinib. A trend toward improvement in overall survival (OS), the trial’s other primary endpoint, was also observed for WELIREG plus LENVIMA (HR=0.85 [95% CI, 0.68-1.05]; p=0.06075). The median OS was 34.9 months (95% CI, 27.5-NR) for WELIREG plus LENVIMA versus 27.6 months (95% CI, 24.0-31.4) for cabozantinib. The trial is continuing, and OS will be evaluated at a subsequent analysis per the clinical trial protocol. Regarding secondary endpoints, at the first interim analysis with a median follow-up of 19.6 months (range, 9.9-39.8), WELIREG plus LENVIMA met ORR, demonstrating a statistically significant improvement compared to cabozantinib. A confirmed ORR of 52.6% (95% CI, 47.3-57.7) was observed for WELIREG plus LENVIMA versus 39.6% (95% CI, 34.6-44.8) for cabozantinib. At the second interim analysis with a median follow-up of 29.0 months, the median DOR was 23.0 months (95% CI, 2.0-44.3+) for WELIREG plus LENVIMA versus 12.3 months (95% CI, 1.8+-35.9+) for cabozantinib. WELIREG plus LENVIMA was administered to 370 patients and cabozantinib was administered to 371 patients. Grade ≥3 treatment-related adverse events (TRAEs) occurred in 71.6% of patients receiving WELIREG plus LENVIMA versus 65.8% of patients receiving cabozantinib. Adverse events led to treatment discontinuation in 11.1% of patients receiving WELIREG plus LENVIMA and in 11.3% of patients receiving cabozantinib, respectively. Serious adverse events were observed in 51.6% of patients receiving WELIREG plus LENVIMA versus 43.9% of patients receiving cabozantinib, and AEs led to death in 5.4% of patients (two were treatment-related: thrombotic microangiopathy [n=1] and pneumonitis [n=1]) versus 3.2% (one was treatment-related: hemoptysis [n=1]) of patients, respectively.About the Eisai and Merck & Co., Inc., Rahway, NJ, USA Strategic CollaborationIn March 2018, Eisai and Merck & Co., Inc., Rahway, NJ, USA through an affiliate, entered into a strategic collaboration for the worldwide co-development and co-commercialization of LENVIMA. Under the agreement, the companies jointly develop, manufacture and commercialize LENVIMA, both as monotherapy and in combination with Merck & Co., Inc., Rahway, NJ, USA’s anti-PD-1 therapy, KEYTRUDA, and HIF-2α inhibitor, WELIREG.Eisai’s focus on cancerEisai acknowledges “Oncology” as one of its key strategic areas, and will continue to focus on the discovery and development of anti-cancer drugs within drug discovery domains including “microenvironment”, “protein integrity and homeostasis”, and “cell lineage and cell differentiation” under the Deep Human Biology Learning (DHBL) drug discovery and development organization. Eisai aspires to discover innovative new drugs with new targets and mechanisms of action from these domains, with the aim of contributing to the cure of cancers.6. About EisaiEisai’s Corporate Concept is “to give first thought to patients and people in the daily living domain, and to increase the benefits that health care provides.” Under this Concept [also known as our human health care (hhc) Concept], we aim to effectively achieve social good in the form of relieving anxiety over health and reducing health disparities. With a global network of R&D facilities, manufacturing sites and marketing subsidiaries, we strive to create and deliver innovative products to target diseases with high unmet medical needs, with a particular focus in our strategic areas of Neurology and Oncology.In addition, our continued commitment to the elimination of neglected tropical diseases (NTDs), which is a target (3.3) of the United Nations Sustainable Development Goals (SDGs), is demonstrated by our work on various activities together with global partners. For more information about Eisai, please visit www.eisai.com (for global headquarters: Eisai Co., Ltd.), us.eisai.com (for U.S. headquarters: Eisai Inc.) or www.eisai.eu (for Europe, Middle East, Africa, Russia, Australia, and New Zealand headquarters: Eisai Europe Ltd.), and connect with us on X (U.S. and global), LinkedIn (for U.S. and EMEA) and Facebook (global).Merck & Co., Inc., Rahway, NJ, USA’s Focus on CancerEvery day, we follow the science as we work to discover innovations that can help patients, no matter what stage of cancer they have. As a leading oncology company, we are pursuing research where scientific opportunity and medical need converge, underpinned by our diverse pipeline of more than 25 novel mechanisms. With one of the largest clinical development programs across more than 30 tumor types, we strive to advance breakthrough science that will shape the future of oncology. By addressing barriers to clinical trial participation, screening and treatment, we work with urgency to reduce disparities and help ensure patients have access to high-quality cancer care. Our unwavering commitment is what will bring us closer to our goal of bringing life to more patients with cancer. For more information, visit https://www.merck.com/research/oncologyAbout MSDAt MSD (the name by which Merck & Co., Inc., Rahway, NJ, USA, is known outside of the United States and Canada), we are unified around our purpose: We use the power of leading-edge science to save and improve lives around the world. For more than 130 years, we have brought hope to humanity through the development of important medicines and vaccines. We aspire to be the premier research-intensive biopharmaceutical company in the world – and today, we are at the forefront of research to deliver innovative health solutions that advance the prevention and treatment of diseases in people and animals. We foster a diverse and inclusive global workforce and operate responsibly every day to enable a safe, sustainable and healthy future for all people and communities. For more information, visit www.msd.co.jp and connect with us on Facebook, Twitter, and YouTube.Ferlay J, Ervik M, Lam F, Laversanne M, Colombet M, Mery L, et al. (2024) Global Cancer Observatory: Cancer Today. Lyon, France: International Agency for Research on Cancer. Available from: https://gco.iarc.who.int/media/globocan/factsheets/cancers/29-kidney-fact-sheet.pdf, accessed 27 Mar 2026.Ferlay J, Ervik M, Lam F, Laversanne M, Colombet M, Mery L, et al. (2024) Global Cancer Observatory: Cancer Today. Lyon, France: International Agency for Research on Cancer, Available from: https://gco.iarc.who.int/media/globocan/factsheets/populations/392-japan-fact-sheet.pdf, accessed 27 Mar 2026.National Comprehensive Cancer Network. NCCN Clinical Practice Guidelines in Oncology: Kidney Cancer. 2025; 2026 Version 1. Rose TL and Kim WY. Renal cell carcinoma: a review. JAMA. 2024 Sep 24;332(12):1001– 10.Media InquiriesEisai Co., Ltd.Public Relations DepartmentTEL: +81 (0)3-3817-5120MSD K.K.Communications DivisionTatsuro MuraseTEL: +81 (0)70-8700-0112 Copyright 2026 JCN Newswire via SeaPRwire.com. All rights reserved. www.jcnnewswire.com

迅策科技業績環比激增449% 結構性重估或進入千億市值陣營?

香港, 2026年3月27日 - (亞太商訊 via SeaPRwire.com) - 隨著人工智慧加速邁向推理階段,企業級AI迎來規模化落地,Token消耗呈指數級攀升,資料需求進入全新發展階段。在這一趨勢下,高品質、結構化、場景化的專業資料,正成為AI時代企業構建核心戰略競爭能力的關鍵所在。作為中國領先的AI即時資料基礎設施及分析服務商,迅策科技得益于賽道紅利,憑藉全鏈路技術能力與多元增長引擎驅動,正加速確立其在AI資料層的核心地位。隨著智慧經濟新形態的全面展開,這家深耕十年的企業正迎來結構性價值重估的視窗期。Token價值重構:讓每一次資料調用都可量化、可計價迅策科技成立於2016年,歷經十年發展,已構建起覆蓋資料獲取、清洗、標準化、即時計算至大模型調優的全鏈路技術體系。公司以AI Data Agent為核心,專注於毫秒級即時資料處理,服務領域涵蓋金融、城市運營、高端製造、醫療、機器人、衛星、低空經濟、電力、電網及能源等多元化產業。在AI推理時代開啟的當下,Token正從"燃料"進化為"硬通貨"。如何將每一個Token的價值最大化,成為大模型推理階段的核心命題。當前,通用大模型普遍採用"用算力換精度"的策略,每一次推理都伴隨著大量無效Token消耗。一旦推理失敗,前期投入的Token全部作廢——這是通用AI面臨的共同困境。相比之下,垂類AI解決方案則是用行業資料為通用大模型安裝一個"外腦"。其核心在於用業務模型優化推理路徑,提前判斷任務可行性,從源頭避免Token浪費。長期深耕專業垂類資料建模領域的迅策科技,憑藉其多年積累的高品質、場景化垂類資料,相當於為每一次Token調用加裝了"增效器",在消耗 Token 時換取更高精度的結果,實現最高的產出確定性。更為關鍵的是,公司正在構建全鏈路的資料計量、計費、結算能力,使每一次資料調用,都可量化、可計價,通過提升每單位Token的有效性,為客戶帶來更高的業務價值。圍繞這一思路,迅策科技的平臺採用"樂高式"模組化架構,讓客戶可以根據自身需求靈活組合模組,實現"按需裝配、隨需而變",建立深度黏性。公司在定價與收費模式上亦遵循靈活設定,基於模組數量、處理速度等維度,銷售採用訂閱制、交易制以及按Token收費制的模式,以精准匹配客戶需求。目前,迅策科技正全力構建全鏈路的資料計量與結算體系,探索按大模型調用次數與模組應用個數等維度計價,讓客戶為"有效Token"付費,而不是為算力消耗買單。業績拐點已現,盈利能力得到驗證在Token價值重構背景與商業模式創新的推動下,迅策科技業績表現強勁,迎來歷史性拐點:2025年下半年,公司實現經調整淨利潤0.5億元,首次實現半年度正向盈利。此外,公司在2025年上半年實現營收1.98百萬元,下半年營收躍升至10.87百萬元,環比激增449%。公司在高速擴張的同時,盈利能力已開始實質性釋放。全年來看,公司實現營業收入達1,284.66億元,較上年同期大幅增長103.28%,成功跨越"十億營收"這一關鍵門檻,標誌著公司已從早期技術驅動的初創階段,正式邁入可規模化複製的平臺化發展新紀元。此外,2025年公司綜合毛利約為人民幣792.08百萬元,較上年度約人民幣484.63百萬元大幅增加63.44%。經調整淨虧損方面,扣除一次性非經常性損益後,公司2025年度經調整淨虧損為人民幣54.84百萬元,較2024年度的82.37百萬元大幅收窄33%。值得注意的是,2025年公司綜合毛利率達62%,不僅高於以AI晶片為核心業務的寒武紀(55%),更遠超通用大模型公司Minimax(25.4%),體現出其在AI資料基礎設施領域獨特的高價值卡位元與商業模式韌性。在研發投入方面,迅策科技亦保持了高效的增長轉化。2025年公司研發開支達450.44百萬元,研發支出占收入比重為48%,驅動營業收入實現105%的同比增長;相比之下,Minimax研發支出占比高達219%,收入增幅為159%。迅策以更低的研發強度,實現了接近同等級別的擴張速度。隨著收入規模持續擴大、新行業毛利逐步收斂,公司短期盈利目標為實現經調整淨利潤迎來拐點。未來隨著已投入行業陸續進入毛利收斂期,以及Token付費與分成模式加速落地,公司淨利率有望加速提升。多元增長引擎驅動,業務結構持續優化業績的強勁增長並非偶然,背後是迅策科技多維驅動、系統推進的增長邏輯。加速跨行業複製。公司目前覆蓋9大行業,對標Palantir的17個行業,橫向拓展空間廣闊。迅策科技正加速向資管、電信、電力、城市管理、高端製造、醫療、能源、機器人訓練平臺、商業航太等國家重點發展的行業縱深拓展。每進入一個新行業,公司先用3-5年完成行業資料沉澱,隨後便可實現同行業客戶的快速複製推廣。商業模式驅動客戶價值深耕。 隨著客戶從單一模組走向多模組部署、從局部試用走向核心業務流程嵌入,ARPU值仍有顯著提升空間。通過Token調用次數、模組應用數量及單次Token價值的協同提升,公司將打開全新的增長空間。穩步開拓海外業務,構建全球化佈局。公司規劃2026年海外收入占比提升至10-15%,2027-2028年持續提升全球化戰略,為長期增長開闢新的空間。構建戰略合作生態,與算力及演算法上下游深度綁定。迅策科技正與國內頭部GPU廠商及大模型公司深度合作,構建"底層算力+上層應用+資料治理"的一站式解決方案,進一步鞏固其在AI資料層的核心地位。開拓前沿應用,搶佔未來產業制高點。從機器人資料平臺到商業航太、低空經濟、電力電網,迅策科技率先將AI基礎設施延伸至對即時性、可靠性要求極高的新興領域,這些對資料即時性、可靠性要求極致的場景,正是公司技術優勢的最佳試金石。公司將持續加大在前沿領域的研發投入,以尖端場景錘煉技術能力,為未來發展開闢高增長、高價值的新賽道。 從資料服務商到AI經濟核心基礎設施,構建深厚競爭壁壘宏觀層面來看,人工智慧資料領域正迎來五大趨勢的深度交匯:AI Agent時代對即時、安全、高品質資料的需求爆發;垂類模型崛起使專業資料成為行業智慧化升級的關鍵要素;Open Claw等新一代AI作業系統將資料介面標準化,迅策科技正成為核心資料Token供應商;Token化付費成為資料要素市場的新範式;資料資產入表政策落地,企業對資料治理的剛性投入需求激增。在這五大趨勢的交匯點上,迅策科技逐步構築起長期發展的堅實底層邏輯。迅策科技不再只是資料基礎設施提供商,而是連接模型、算力、雲廠商的"連接器"與"賦能者"。向上連接模型,向下連接算力,橫向協同雲廠商,最終為客戶提供不可替代的資料價值。公司強調,其與通用大模型公司是天然的上下游合作關係,而非競爭關係。正如GPU廠商與模型公司深度合作一樣,迅策科技的價值在於:客戶使用的模型越多,公司的服務機會越多,為客戶創造的價值也越多。值得關注的是,與市場上僅做資料清洗、或僅做計算引擎的單一模組廠商不同,迅策科技的核心差異在於全流程覆蓋與為結果負責的能力。從資料獲取、清洗、標準化、建模、即時計算,到模型調優,提供端到端解決方案,確保最終輸出給客戶的資料是乾淨的、準確的、即時的、可被模型秒級調用的。同時,公司深度嵌入客戶的私有雲或本地系統,扮演"資料管家"角色,形成極高的客戶粘性與競爭壁壘。目前,公司產品與解決方案擁有超過300多個功能模組,覆蓋從資料基礎設施到上層分析的全場景。2025年,公司的付費客戶活躍量達到230家,客戶留存率高達90%。ARPU值從2024年的272萬元,再大幅提升2025年559萬元,同比增幅超過103%。當演算法走向開源,算力趨於標準化,真正拉開差距的,是資料——尤其是經過深度治理、能夠驅動大模型的行業資料。迅策科技憑藉十年深耕,已在這一領域構建起深厚的護城河。結語從早期私募工具到跨行業的AI資料基建,從"模組供應商"到"Token計價平臺",迅策科技始終致力於讓資料成為真正可流動、被調用、可驅動決策的稀缺資源。在智慧經濟新形態加速到來的今天,這家公司正站在結構性重估的起點上, 或進入千億市值陣營。它不是任何人的競爭者,而是所有人都需要的合作夥伴。 Copyright 2026 亞太商訊 via SeaPRwire.com. All rights reserved. www.acnnewswire.com

iGaming In-App Traffic Scaling Now Prioritizes Performance Over Volume

(AsiaGameHub) -   Traffy, a performance marketing agency that focuses on in-app traffic, has observed a significant change in the way iGaming campaigns are scaled today. The days of "launch and forget" strategies in iGaming have ended. The market has grown increasingly competitive, and user expectations have risen dramatically. Campaign scaling is no longer purely a numbers game — achieving success now hinges on sophisticated analytics, rapid response to user behavior, and the quality of traffic. Market Evolution Previously, scaling operated on a straightforward principle: increasing traffic would automatically boost conversions. That methodology is now obsolete. Users have grown more discerning, and both Cost Per Acquisition (CPA) and Return on Investment (ROI) are now directly linked to user behavior after making their initial deposit. When advertisers neglect to monitor critical performance metrics during the initial 72-hour window — such as user engagement, repeat deposits, and First-Time Deposit (FTD) conversion — they lose budget control, and scaling becomes speculative rather than strategic. Modern Scaling Requirements Today's campaign scaling demands a far more systematic methodology: Conducting funnel analysis during the first 72 hours to rapidly pinpoint effective configurations Implementing traffic segmentation and rigorous quality assurance measures Maintaining ongoing surveillance of user engagement, repeat deposit patterns, and FTD conversion metrics When campaigns fail to demonstrate positive performance trends within the initial three-day period, they are terminated promptly. This approach enables teams to limit financial losses and redirect budgets to better-performing initiatives. Traditional Approach Limitations Numerous operators and affiliates continue to depend on obsolete tactics that hinder effective scaling: Concentrating exclusively on CPA metrics while ignoring unit economics and overall profitability Expanding campaigns broadly without adequate traffic segmentation Failing to employ predictive analytics during campaign launch phases Undervaluing traffic quality and exposure to fraudulent activity These shortcomings result in inconsistent performance, increasing Cost Per Install (CPI), and diminished control over ROI. Traffy's Methodology At Traffy, we develop scalable infrastructure specifically engineered to handle in-app traffic through a performance-centric lens. Traffic quality management: employing black and white lists, conducting continuous audits, and utilizing integrated fraud detection analytics AI-powered optimization: leveraging algorithms that forecast campaign performance and automatically shift budgets to the most effective configurations Performance-centric focus: executing real-time analysis during the critical first 72 hours, implementing deep segmentation, and persistently tracking key performance indicators and ROI This methodology enables us to expand only traffic sources that demonstrate proven profitability, thereby mitigating risks and enhancing scalability predictability. Conclusion A performance-driven methodology has become indispensable for scaling in-app campaigns within the iGaming sector. Success hinges on comprehensive analytics, sophisticated traffic segmentation, predictive modeling, and rigorous management during the initial 72-hour window. The market landscape has evolved — and victors are no longer those who simply increase volume, but those who prioritize scaling high-quality traffic. At Traffy, this philosophy forms the foundation of our campaign development and scaling processes, guaranteeing sustainable expansion and quantifiable results for our partners. This article is provided by a third-party. AsiaGameHub (https://asiagamehub.com/) makes no warranties regarding its content. AsiaGameHub delivers targeted distribution for iGaming, Casino, and eSports, connecting 3,000+ premium Asian media outlets and 80,000+ specialized influencers across ASEAN.

Hitachi and MUFG Bank expand NextGen model to finance vehicles and charging infrastructure for decarbonized mobility

TOKYO, Mar 27, 2026 - (JCN Newswire via SeaPRwire.com) - Hitachi, Ltd. (TSE: 6501, “Hitachi”) and MUFG Bank, Ltd. (“MUFG Bank”), a consolidated subsidiary of Mitsubishi UFJ Financial Group, Inc. (TYO: 8306, “MUFG”) today announced a new Memorandum of Understanding (MoU) to expand NextGen, their business co-creation model. Building on their collaboration launched in May 2024*1 and further developed as announced in May 2025*2 , NextGen combines Hitachi’s technology and operational expertise with MUFG’s financial capabilities to accelerate the transition to decarbonized mobility.*1 MUFG’s Business Co-Creation and Investment into UK Battery as a Service project by Hitachi ZeroCarbon May 2024*2 Hitachi ZeroCarbon and MUFG unite technology expertise with financial support to accelerate fleet electrification May 2025NextGen was initially validated through a UK pilot project with First Bus, where the parties collaborated via a special purpose vehicle (SPV) to support the procurement and operation of electrification assets under a Battery-as-a-Service model. This expanded MoU extends NextGen beyond battery-focused structures, enabling broader and more scalable deployment across additional markets outside the UK and across a wider range of asset classes. These include emobility assets such as electric vehicles and charging infrastructure, associated energy management systems, and potentially extending to energy hubs supporting industrial assets, power grids and data centers.Hitachi and MUFG Bank will also develop and scale SPV structures to finance decarbonized mobility assets for fleet and transport operators. This approach removes capital constraints and accelerates implementation, enabling operators to focus on their core transport services. From Hitachi’s side, the initiative is led by its Strategic SIB Business Unit, bringing together expertise from across Hitachi including Hitachi Energy, as ‘One Hitachi’. Hitachi will also provide managed services for asset performance and lifecycle optimization, supported by data-driven solutions from Hitachi ZeroCarbon. Through this initiative, Hitachi aims to further advance and streamline mobility and charging infrastructure operations by expanding HMAX by Hitachi, a suite of next-generation solutions that embodies Lumada 3.0, differentiated by deep domain knowledge and AI.Electrifying commercial transport at pace will require an unprecedented deployment of vehicles, charging and energy infrastructure - alongside innovative financing models to support it. Global investment in electrified transport reached around US$750 billion in 2024, making it the largest segment of the energy transition worldwide*3 - yet many fleet operators face limited access to capital and the operational complexity of transitioning at scale. Against this backdrop, Hitachi and MUFG Bank aim to expand NextGen as a repeatable model to accelerate implementation by combining structured asset financing with managed services and data-driven optimization.*3 Sources: BloombergNEF’s Energy transition Investment Trends 2025In demonstration of the expanded pipeline, Hitachi ZeroCarbon and MUFG Bank have also entered into an MoU with Boreal Norge AS and its subsidiary Boreal Buss AS, one of Norway’s primary transport operators, providing transport services across several counties and employing around 3,000 employees across its fleet, which includes over 850 buses and 35 ferries. The parties will explore how they can support Boreal’s transition planning, de-risk operations, optimize services and strengthen competitiveness as concessions evolve.Jun Taniguchi, Senior Vice President and Executive Officer, CEO of Strategic SIB Business Unit, at Hitachi, Ltd. said:“We are delighted to advance this partnership which combines Hitachi’s deep expertise in social infrastructure and digital technologies with MUFG Bank, Ltd.’s financial strength to accelerate the transition to a decarbonized society. By improving the performance of assets such as batteries and charging infrastructure through Hitachi’s digital services led by HMAX, we can truly help customers optimize the total cost of ownership. This partnership embodies our One Hitachi approach, leveraging our diverse capabilities across the Group to support our customers in achieving their net-zero ambitions.”Masakazu Osawa, Senior Managing Executive Officer Chief Executive, Japanese Corporate & Investment Banking Business Unit of MUFG Bank, Ltd., said:“Building on MUFG’s Business Co‑Creation and Investment approach, this collaboration with Hitachi aims to create value through strategic partnerships that improve society and the environment. For the global EV market, our focus is not only on strengthening Hitachi’s leading position in Battery as a Service, but also on fostering a holistic value chain — including second‑ life battery markets — that supports the acceleration of electric mobility and the achievement of 2050 net‑zero targets. Together with our partners, we are committed to co‑creating sustainable businesses that become a driving force for progress worldwide.”Nikolai Knudsmoen Utheim, Group CEO, Boreal Norge AS said:“Our priority has always been to deliver first-class transport services to our customers, whether that’s on the road, rail or over water. In exploring how we can unlock the power of electrified fleets, we can not only deliver more sustainable operations, but upgrade our infrastructure and thread technology across our entire business model for more efficient, smart transport and energy management.”About Hitachi, Ltd.Through its Social Innovation Business (SIB) that brings together IT, OT (Operational Technology) and products, Hitachi contributes to a harmonized society where the environment, wellbeing, and economic growth are in balance. Hitachi operates globally in four sectors – Digital Systems & Services, Energy, Mobility, and Connective Industries – and the Strategic SIB Business Unit for new growth businesses. With Lumada at its core, Hitachi generates value from integrating data, technology and domain knowledge to solve customer and social challenges. Revenues for FY2024 (ended March 31, 2025) totaled 9,783.3 billion yen, with 618 consolidated subsidiaries and approximately 280,000 employees worldwide. Visit us at www.hitachi.com.About MUFGMitsubishi UFJ Financial Group, Inc. (MUFG) is one of the world’s leading financial groups. Headquartered in Tokyo and with over 360 years of history, MUFG has a global network with approximately 2,000 locations in more than 40 countries. The Group has about 150,000 employees and offers services including commercial banking, trust banking, securities, credit cards, consumer finance, asset management, and leasing. The Group aims to “be the world’s most trusted financial group” through close collaboration among our operating companies and flexibly respond to all of the financial needs of our customers, serving society, and fostering shared and sustainable growth for a better world. MUFG’s shares trade on the Tokyo, Nagoya, and New York stock exchanges. For more information, visit https://www.mufg.jp/english.About BorealBoreal is a leading mobility provider, operating buses, fast ferries, passenger ferries and trams in Norway and Sweden. We remain firmly committed to our societal mission of encouraging more people to travel collectively. At the same time, we are more than public transport. As the only company operating buses, ferries, fast ferries, trams and tourism services, we deliver integrated mobility solutions and travel experiences. Although Boreal is a young company in name, its heritage extends back more than 150 years. The company has around 3,000 employees and is headquartered in Stavanger, Norway. Copyright 2026 JCN Newswire via SeaPRwire.com. All rights reserved. www.jcnnewswire.com

Analogue 2025 Annual Results Profit Attributable to Owners of the Company Increases 23.5% to HK$167.0 Million

HONG KONG, Mar 27, 2026 - (ACN Newswire via SeaPRwire.com) - Analogue Holdings Limited (“Analogue” or the “Company”, together with its subsidiaries, the “Group”) (stock code: 1977), a leading provider of electrical and mechanical (“E&M”) engineering solutions, and information and communications technology services for smart cities, today announced its annual results for the year ended 31 December 2025 (“the Year” or “FY2025”) with net profit growth, contracts-in-hand achieving another record high and order intake more than doubled, providing a solid business foundation for the coming three years and beyond.Financial Highlights- Profit attributable to owners of the Company increased 23.5% to HK$167.0 million.- Contracts-in-hand surged 61.8% to HK$17,878.7 million, hitting another record-high, made possible by a 113.7% increase in order intake to HK$12,913.6 million during the Year.- The intake of new maintenance contracts for housing programmes, environmental projects and lifts and escalators increased 51.4% to HK$1,669 million, reinforcing the recurring revenue stream.- The Group maintained a strong cash position, with bank balances and cash of HK$1,020.8 million and gearing ratio reduced to 10.1% for FY2025 from 26.2%.- The Board has resolved to pay a second interim dividend of HK2.9 cents per share. Total dividend for the year amounted to HK5.5 cents per share with 25.6% increment year-on-year.Chairman Dr Mak Kin Wah said, “The Year 2025 saw profound changes around the world, with challenges and yet also opportunities. Our Group has continued to stride forward: upholding what we commit by delivering the fundamentals well, striving for continuous improvement to make transformation actionable, investing in technology advancement and productivity, and bringing Hong Kong’s engineering excellence to the world. We are pleased to report that the Group achieved profit growth, secured a record level of contracts-in-hand, and continued to build on our international market presence. These accomplishments highlight our distinctive comprehensive capability across diverse business segments, our commitment to excellence, and our leadership in advanced engineering techniques.”“Supported by strong cashflow, we are in a strong position to take on additional work where appropriate and to seize high-value opportunities as they arise. We will continue to stay agile and focused on capturing opportunities across our broad portfolio, build on our competitive strengths through continuous improvement, and reinforce the use of innovative solutions that enhance quality, safety and performance. We remain steadfast in our commitment to our customers, recognising that this is fundamental to earning their trust and cultivating enduring, strategic partnerships. Guided by our motto – ‘We Commit. We Perform. We Deliver’ – we will continue to maximise value for customers, shareholders, suppliers and stakeholders, while contributing to the communities we serve.”Business Review: Building Services- This segment remains the largest revenue contributor, with revenue reaching HK$3,279 million.- Contracts-in-hand reached a record-high level of HK$8,297 million with the total value of new contracts secured in FY2025 doubled to HK$6,470 million. The Group’s competitive edge in multidisciplinary packaged projects and its industry leadership in innovative MiMEP and other new engineering techniques helped it to secure major contracts.- With strategic investments to accelerate innovation and modern manufacturing facilities in Zhuhai and Hong Kong, the Group continues to lead in MiMEP and DfMA technologies.- Following the successful acquisition of a property management licence, the Group expanded its business to deliver integrated solutions across the entire building lifecycle. This new capability, spanning construction, maintenance, operations and long-term facility management, creates a potential revenue stream that complements core services.- Through continuous development of innovative technologies and operational optimisation, the segment is positioning itself to maintain the market competitiveness while exploring opportunities in other markets in Southeast Asia.Environmental Engineering- This segment achieved record-high contracts-in-hand and order intake, increasing 86.9% and 253.7% to HK$8,094 million and HK$5,355 million respectively. Segment revenue also increased by 18.0% year-on-year to HK$1,591 million.- The segment maintained active tendering throughout the period and was awarded significant contracts, including contracts of a record-breaking value to relocate sewage treatment works in Sha Tin to caverns, sewage pumping station at Ma On Shan and more.- Formed a joint venture company in Qingyang city to explore the operation and maintenance business in the Chinese Mainland.- Explored project opportunities in Asia and the Middle East and the expansion of its expert services into Europe.Information, Communications and Building Technologies (“ICBT”)- Segment revenue remained at HK$630 million. Contracts-in-hand totalled HK$852 million at the year end, and order intake was HK$523 million during the Year.- This segment continued to reinforce its leadership in green and intelligent building solutions under the DigiFusion brand, to enable the development of smarter, more sustainable urban environments.- Continued to leverage ATAL Tower as a platform for developing innovative technologies and broaden its technological capabilities through strategic collaborations with leading manufacturers in the Chinese Mainland and around the world, to strengthen its ability to deliver scalable, high-performance solutions across a wide range of sectors.Lifts and Escalators- Revenue and order intake increased 11.0% to HK$587 million and by 3.2% to HK$566 million respectively.- Transel Elevator & Electric Inc. (TEI), the associate company in the United States (US), secured a contract for the world-class vertical transportation system in the iconic 56-storey luxury hotel skyscraper on the border of Times Square in New York. TEI also further strengthened its market position by extending its footprint into the Southeastern part of US.- Actively built on its presence in the UK and broadened its network across other international markets, reinforcing its global ambitions in vertical transportation solutions.- Machine-Room-Less lift products continued to gain traction in key international markets- Streamlined the manufacturing processes of Nanjing factory, broadened its product portfolio and strengthened the overall product quality, aligning with the Group’s global vision and reaffirming its commitment to delivering reliable, high-performance vertical transportation solutions.For further details of the 2025 Annual Results, please refer to the announcement filed with The Stock Exchange of Hong Kong Limited.About Analogue Holdings LimitedEstablished in 1977, Analogue Holdings Limited is a leading provider of electrical and mechanical (“E&M”) engineering solutions and information and communications technology (“ICT”) services for smart cities, with headquarters in Hong Kong and operations in the Chinese Mainland, Macau, the United States, the United Kingdom, Germany, Singapore and Malaysia. Serving a wide spectrum of customers from public and private sectors, the Group provides multidisciplinary and comprehensive E&M engineering and technology services in four major segments, including Building Services, Environmental Engineering, Information, Communications and Building Technologies (“ICBT”) and Lifts & Escalators.The Group also manufactures and sells lifts and escalators internationally and has entered into an alliance with Transel Elevator & Electric Inc. (“TEI”), one of the largest independent lifts and escalators companies in New York, the United States. The Group’s associate partner, Nanjing Canatal Data-Centre Environmental Tech Co., Ltd. (603912.SS), specialises in manufacturing of precision air conditioners. Copyright 2026 ACN Newswire via SeaPRwire.com. All rights reserved. www.acnnewswire.com

安樂工程公佈2025年全年業績 本公司擁有人應佔溢利增23.5%至1.670億港元

香港, 2026年3月27日 - (亞太商訊 via SeaPRwire.com) - 領先的機電工程與智慧城市的資訊及通訊科技服務供應商安樂工程集團有限公司(「安樂工程」或「公司」,連同附屬公司統稱「集團」)(股份代號:1977),今天宣佈截至2025年12月31日止年度(「年內」或「2025財政年度」)的全年業績,除淨利潤錄得增長,集團的手頭合約更再創新高,訂單額增長逾倍,為未來三年及往後的發展奠下穩固基礎。財務摘要- 本公司擁有人應佔溢利按年增23.5%至1.670億港元- 手頭合約增61.8%至178.787億港元,再創歷史新高,受惠於年内訂單額增長113.7%至129.136億港元- 新增維修保養合約涵蓋房屋項目、環保項目以及升降機及自動梯,合約額增51.4%至16.69億港元,鞏固經常性收入來源- 集團維持強健現金水平,銀行結餘及現金為10.208億港元,資產負債比率則由26.2%降低至2025財政年度的10.1%- 董事會已決議派付第二次中期股息每股2.9港仙;全年合共派息每股5.5港仙,較上年度増25.6%主席麥建華博士表示:「2025年見證了全球的重大變化,挑戰與機遇並存。集團穩步向前,以謹慎履行承諾作堅實基礎,不斷精益求精,更推動革新落到實處、投資提升技術及生產力,引領香港工程的卓越實力踏上環球市場。我們欣然宣布,集團實現了利潤增長,更創下歷史新高的手頭合約水平,並持續鞏固在國際市場的影響力。這些成就彰顯了我們在各個業務領域的綜合能力,對卓越品質的承諾,以及在先進工程技術方面的領導地位。」「憑著充裕的現金流支持,我們具實力適時開展更多工程項目,並在高價值商機出現時抓緊機會。我們將繼續保持靈活專注,積極把握集團廣泛業務組合中的機遇,透過持續提升我們具競爭力的優勢,並強化應用創新解決方案,以提升工程品質、安全和表現。我們深知為客戶堅定不移地履行承諾,是贏得他們信任及維繫持久夥伴關係的基礎。秉持『重承諾、慎履行、獻成果』的座右銘,我們將繼續為客戶、股東、供應商和其他持份者創造最高利益,同時為我們所服務的社區作出貢獻。」業務回顧:屋宇裝備工程- 此業務板塊繼續成為集團最大的收益來源,收益達32.79億港元。- 手頭合約創下歷史新高,達82.97億港元,於2025財政年度新簽合約增長一倍達64.70億港元。集團在跨多專業的綜合項目中擁有競爭優勢,並有賴在創新的機電裝備合成法和其他新工程技術方面的領導地位成功取得重要合約。- 憑藉策略性投資以加快創新,並在珠海和香港發展現代化製造設施,集團得以在機電裝備合成法和裝配式設計技術方面繼續領先同儕。- 集團通過成功取得物業管理牌照擴大業務以提供可橫跨整個建築週期的綜合解決方案。此涵蓋建造、維修保養、營運,以至長期的設施管理的新能力,開拓了潛在的收益來源,與核心服務互補優勢。- 透過不斷開發創新技術和優化營運,此業務板塊強化自身定位以維持在市場中的競爭優勢,同時探索東南亞其他市場的發展機遇。環境工程- 此業務板塊的手頭合約與新增訂單額創下歷史新高,分別按年增加86.9%及253.7%至80.94億港元及53.55億港元。同時,業務收益按年增加18.0%至15.91億港元。- 此業務板塊於年內維持積極參與投標,並成功贏得標誌性合約,包括合約額破紀錄的搬遷沙田污水處理廠往岩洞、馬鞍山污水泵房等工程項目。- 於慶陽市開立了合營企業,以拓展中國內地的營運及維修業務。- 探索在亞洲和中東地區的項目機遇,並將專業服務拓展至歐洲市場。資訊、通訊及屋宇科技(「ICBT」)- 業務收益維持在6.30億港元,手頭合約價值截至2025年末為8.52億港元,年內新增訂單額為5.23億港元。- 此業務板塊持續以DigiFusion品牌鞏固其在綠色及智慧屋宇解決方案的領導地位,有助打造更智慧化、更可持續的城市環境。- 持續憑藉安樂工程大廈作為平台以研發創新技術,並透過與中國內地及環球領先生產商的策略合作持續擴大技術能力,從而加強在多個範疇的能力以提供可擴大規模的高效解決方案。升降機及自動梯- 收益與新增訂單額分別按年增加11.0%至5.87億港元,以及增加3.2%至5.66億港元。- 集團位於美國的聯營公司Transel Elevator & Electric Inc (「TEI」)取得重大合約,在聳立於紐約時代廣場旁的地標性56層摩天豪華酒店內提供世界級垂直運輸系統。TEI亦將業務版圖拓展至美國東南部,進一步鞏固其市場地位。- 積極加強在英國的業務,並擴大在其他國際市場的網絡,強化在垂直運輸解決方案領域的全球發展的雄心。- 無機房升降機產品繼續在主要國際市場取得進展。- 南京工廠簡化了生產流程,擴大產品種類,並提高了整體產品質量。這些提升正好配合集團的環球視野,肯定其承諾,矢志提供可靠和高效的垂直運輸解決方案。有關2025年度業績詳情,請參閱已呈交香港聯合交易所有限公司的公告。關於安樂工程集團有限公司安樂工程集團有限公司成立於1977年,為領先的機電工程與智慧城市的資訊及通訊科技服務供應商,總部設於香港,業務遍及中國內地、澳門、美國、英國、德國、新加坡及馬來西亞。本集團為公共和私營機構提供跨專業綜合機電及技術服務,涵蓋屋宇裝備工程、環境工程、資訊、通訊及屋宇科技(「ICBT」),以及升降機及自動梯等四大業務板塊。本集團同時製造及向全球銷售升降機及自動梯,並與美國紐約最大獨立升降機及自動梯公司之一 – Transel Elevator & Electric Inc.(「TEI」)達成夥伴關係。本集團的聯營公司南京佳力圖機房環境技術股份有限公司(603912.SS)專門製造精密空調設備。 Copyright 2026 亞太商訊 via SeaPRwire.com. All rights reserved. www.acnnewswire.com

多維驅動全域突破 海天味業2025年交出高品質發展成績單

香港, 2026年3月27日 - (亞太商訊 via SeaPRwire.com) - 3月26日,海天味業(A股:603288;H股:03288)發佈2025年年度業績報告,面對2025年複雜多變的市場環境,憑藉多元產品矩陣、高效運營體系、硬核科技創新,公司在行業變革浪潮中穩健前行,交出一份彰顯行業龍頭實力與高品質發展成色的優異答卷。財報資料顯示,2025年公司核心經營指標穩健增長,實現營業收入288.73億元,同比增長 7.32%。盈利能力同步提升,全年歸母淨利潤70.38億元,同比增長10.95 %;扣非歸母淨利潤68.45億元,同比增長12.81%;調味品主業毛利率41.78%,同比增加3.15個百分點;各項經營資料均創下歷史新高,盈利品質與增長動力雙雙亮眼,彰顯公司硬核實力。豐富的國民產品矩陣,構築多元增長格局豐富完善的國民級產品矩陣,是海天味業實現穩健增長的核心基石。在產品矩陣方面,海天圍繞用戶需求持續推進品類創新,構建起覆蓋全場景烹飪的一站式產品體系,全方位滿足不同消費群體的多樣化需求。得益于豐富的產品矩陣與優異的產品品質,2025年,公司醬油、蠔油、調味醬等核心品類保持穩健發展,分別實現營業收入149.34億元、48.68億元及29.17億元,同比增長8.55%、5.48%及9.29%,構成業務增長的“金字塔基座”。其中,海天醬油產銷量和市場佔有率已連續數十年位居全國第一,海天蠔油的市場佔有率也連續10年位居全國第一,憑藉優質口感與穩定品質,成為千萬家庭與餐飲機構的首選;公司調味醬已形成產品豐富、風味立體、場景多元的產品體系,涵蓋黃豆醬、香辣醬等具備廣泛消費基礎的大單品,同時亦有柱侯醬、海鮮醬、拌飯醬、香菇醬等適用不同烹飪方式的特色醬料,紫蘇醬、桂林風味辣椒醬等適合不同地域口味的風味醬料,以及蔥油拌麵醬、重慶小面調料等便捷化調味醬,有效滿足用戶需求。此外,為順應消費者對醋類產品的細分化需求,公司堅持「傳統醋+特色醋」的產品佈局,同時不斷推陳出新,推出有機醋、果醋等多元化產品,形成豐富多元的醋類產品體系,進一步彌補品類空白,擴大市場覆蓋面。截至2025年底,公司擁有7個十億級以上產品系列、超30個億級以上產品系列,產品矩陣的豐富度與完整性持續提升。其中,金標生抽、草菇老抽兩大產品系列已暢銷60餘年,味極鮮醬油、海天上等蠔油兩大產品系列連續10餘年實現單品年收入超10億元,成為支撐公司業績穩健增長的「壓艙石」,其市場認可度與用戶忠誠度持續處於行業領先水準。在保持核心品類穩健增長的同時,海天精准把握消費趨勢變化,持續培育新興增長點,不斷豐富產品矩陣的層次與內涵。報告期內,在領先行業的產品力支撐下,以有機和薄鹽為代表的營養健康系列產品實現營業收入同比增速達48.3%,成為拉動業績增長的新引擎;食醋和料酒業務持續發力,規模優勢和體系化能力逐步顯現,市場佔有率穩步提升,為公司長遠發展注入強勁新動能。​值得關注的是,依託供應鏈規模效應、技術研發與柔性生產三大核心壁壘,海天加速從“調味產品供應商”向“一站式風味解決方案提供商”轉型,深度佈局商用市場,實現To C與To B業務雙輪驅動。截至2025年底,公司已為眾多餐飲連鎖、食品工廠及全球頭部零售品牌提供商用調味品一站式解決方案,成為公司業績增長的重要支撐。堅持以用戶為中心,全域深耕驅動效率與價值雙升堅持以用戶為中心,持續優化運營效率與用戶價值,是海天味業保持行業領先地位的關鍵所在。面對消費渠道的多元化變革,海天立足用戶需求,通過數字化賦能傳統渠道、擁抱新興渠道建設、聯動餐飲及工業渠道,實現效率與價值的雙重躍升,進一步鞏固市場滲透率。在傳統渠道方面,海天依託覆蓋全國的終端網路,借助數字化行銷工具和服務模式創新,持續向下沉市場滲透,並延伸到最終用家和消費者,顯著提高了終端覆蓋品質與消費者觸達效率,同時,通過終端管理的精細化升級,讓存量網點煥發新活力。2025年線下渠道營業收入達257.60億元,同比增長7.85%。線上與即時零售等新興陣地,海天主動適應消費場景的變化,通過規範銷售秩序、強化專業運營,實現新興渠道的高品質發展;針對新興渠道的消費特性,公司還推出線上定制化產品,精准匹配消費群體的需求,逐步構建線上與線下協同互促的健康發展模式,2025年線上渠道增幅高達31.87%。在商用渠道方面,依託柔性供應鏈與「銷研產一體化」快速回應機制,海天為餐飲連鎖和食品工廠提供從通用產品到定制化的一站式調味解決方案,實現「3天打樣、15天交付」的高效回應,大幅提升了客戶體驗與合作粘性。目前,餐飲與工業渠道穩健發展,收入占比持續提升,正成長為公司專業增長的重要動力源,進一步拓寬了公司的增長空間。堅持科技立企與創新,驅動價值鏈全面升級堅持科技立企、創新驅動,是海天味業實現高品質發展的核心動力。作為調味品行業數字化轉型的先行者,公司全面擁抱AI時代,推動人工智能、大數據與傳統釀造技藝深度融合,在守護匠心工藝的同時實現提質增效,推動行業從「傳統釀造」向「智慧釀造」轉型升級。海天味業堅持每年將研發投入保持在營業收入約3%的水準,近十年研發投入累計超65億元,累計擁有各類專利超1,000項,形成了完善的研發體系與創新機制。2025年1月,海天高明生產基地獲得全球醬油釀造行業首家「燈塔工廠」認證,標誌著公司數字化轉型已躋身全球行業標杆,也印證了中國調味品企業在智慧製造領域的領先實力。此外,公司部署端到端供應鏈創新用例,將AI與大數據深度應用於研、產、供、銷各環節,實現全鏈條的數字化、智慧化升級。在數字化全面賦能下,海天供應鏈運營效率顯著提升,訂單準時足額交付率(OTIF)不斷提高,綜合成本穩步下降,充分彰顯智慧製造帶來的效率紅利與競爭優勢。受益於在數字化轉型與高品質發展方面的突出成就,海天味業屢獲殊榮。2025年,公司斬獲「CGF中國供應鏈數字化與可持續韌性發展案例」「全國製造業數字化轉型典型案例」等多項殊榮,得到行業與社會的廣泛認可。同時,由海天主導起草的國家標準《食品數字化工廠通用技術要求》正式發佈,填補了國內食品行業數字化工廠通用技術標準的空白,為食品行業數智化升級提供「海天範式」,充分彰顯了公司的行業帶動力與責任擔當。回望2025年,海天味業以穩健業績、多元佈局、硬核實力,在高品質發展之路上行穩致遠,進一步鞏固了行業龍頭地位。展望未來,公司將繼續堅守匠心、深耕主業,持續優化產品矩陣、深化科技賦能、拓展全球市場,以更優質的產品、更高效的服務、更強勁的創新力,守護中國味道、引領行業升級,書寫中國調味品企業全球化高品質發展的嶄新篇章。 Copyright 2026 亞太商訊 via SeaPRwire.com. All rights reserved. www.acnnewswire.com

Southwest Airlines CEO:開會不等於工作——他正採取行動,每週三至週五下午封鎖行事曆

(SeaPRwire) -   企業領導人正拉響警報:會議已經席捲一切,真正的工作反而被拋在腦後。而西南航空(Southwest Airlines)執行長鮑伯·喬丹(Bob Jordan)是最新就此現象發聲的人士——他主張許多領導人誤將頻繁開會等同於領導能力。 「剛開始擔任領導職務時,很容易將忙碌和開會與領導能力畫上等號,」喬丹在2025年12月《紐約時報》DealBook峰會的執行長座談會上表示。「……我相信我們都有同感,就是根本沒有時間做『實際工作』,反而把開會當成了工作本身。」 多年來,喬丹的解決方案越發簡單直接:保護自己的時間。2026年,他的目標是讓每週三、四、五的下午行程完全空白——禁止任何人在這些時段預約會議。 儘管他承認這種做法對某些企業高管而言可能聽起來「瘋狂」,但他指出,執行長被僱用是為了處理只有他們能做的工作——而當他們陷在一場接一場的會議中時,這種工作幾乎不可能完成。  「這樣你才能專注處理需要投入心力的事,思考當下最重要的議題,打電話給需要溝通的人,」喬丹補充道。 這種策略似乎開始見效。儘管2025年航空業局勢動盪,西南航空仍在2025年10月的季度財報中意外獲利。其股價年增約16.5%。 已聯繫西南航空(Southwest Airlines)請求進一步評論。 會議已成為員工與僱主共同的惡夢 喬丹並非唯一感到困擾的人。會議已成為員工與高管共同的痛點。 疫情期間,會議幾乎扮演了「情感支持」的角色——試圖彌補封鎖期間缺乏面對面互動的空缺。由於無需等待會議室空出,日曆迅速被排滿。 但根據2024年Atlassian的一項研究(訪調四大洲5,000名員工),如今近80%的人表示被海量會議與電話淹沒,幾乎沒有時間完成實際工作。約72%的會議被認為效率低落。 這種反彈促使越來越多高管積極刪減——甚至徹底取消——企業日程中的會議,有時還劃出完全無會議的日子。不過,部分專家警告,徹底取消會議可能危及員工對組織的歸屬感,長期反而可能適得其反。 「會議不需要全數驅逐,只有那些低效、浪費時間的才需要,」就業科技公司Employment Hero執行長兼共同創辦人班·湯普森(Ben Thompson)先前向本刊表示。 輝達(Nvidia)與摩根大通(JPMorgan Chase)如何應對會議氾濫 其他執行長也發展出各自的非傳統策略。 例如,輝達(Nvidia)執行長黃仁勳(Jensen Huang)不會與超過50名的直接下屬進行一對一會議。他表示,這麼做不僅會壓垮自己的日程,還會拖慢團隊解決問題、有效運作與維持透明度的能力。 「我們的公司設計講求敏捷——讓資訊以最快速度流動,讓員工憑『行動能力』而非『已知資訊』獲得授權,」黃仁勳去年在史丹佛大學演講時表示。 摩根大通(JPMorgan Chase)執行長傑米·戴蒙(Jamie Dimon)則採取更直接的方式。在2025年致股東信中,他敦促員工重新思考會議是否有召開的必要。 「這是另一個拖慢我們的例子:會議。消滅會議,」他寫道。「但如果真的要開會,必須準時開始、準時結束——且必須有人主持。每場會議都要有明確目的,並永遠附上後續行動清單。」 隨著摩根大通要求員工每週五天回辦公室,效率變得更加重要。戴蒙強調,會議必須獲得全神貫注。 「開會時不能打瞌睡,不能看郵件,」戴蒙在10月本刊舉辦的「最具影響力女性峰會」上重申。「如果你面前擺著iPad,看起來像是在讀郵件或收通知,我會叫你關掉那該死的東西。這是不尊重的表現。」 本文最初於2026年12月15日發表於.com。 更多領導力相關報導: 瑪麗·巴拉(Mary Barra)儘管掌管市值650億美元的汽車大廠通用汽車(General Motors),仍堅持親筆回覆「每一封」收到的信件 AI時代向所有執行長傳達訊息:適應或淘汰 花旗(Citi)執行長珍·弗雷澤(Jane Fraser)篤信巴菲特(Warren Buffett)處理職場衝突的黃金法則:「永遠、永遠不要在憤怒時回覆那封郵件」 本文由第三方廠商內容提供者提供。SeaPRwire (https://www.seaprwire.com/)對此不作任何保證或陳述。 分類: 頭條新聞,日常新聞 SeaPRwire為公司和機構提供全球新聞稿發佈,覆蓋超過6,500個媒體庫、86,000名編輯和記者,以及350萬以上終端桌面和手機App。SeaPRwire支持英、日、德、韓、法、俄、印尼、馬來、越南、中文等多種語言新聞稿發佈。

Cursor CEO警告:氛圍編程將建立「不穩固的基礎」,最終恐致「系統崩潰」

(SeaPRwire) -   Cursor 或許利用人工智慧來協助程式設計師編碼,但請別稱之為氛圍編碼,執行長暨共同創辦人 Michael Truell 表示。 他解釋道,十年前,程式設計意味著在空白的文書處理器中輸入程式碼並手動編輯。但隨著生成式人工智慧的出現,這種類型的程式設計正迅速成為過去式。 「越來越多情況下,你可以從程式碼中退後一步,要求人工智慧為你執行端到端的任務,」Truell 在十二月的 Brainstorm AI 會議上說道。 然而,他補充說,程式設計師可能不想退得太遠,並指出人工智慧輔助編碼是有層次之分的。 什麼是氛圍編碼? 常被提及的術語「氛圍編碼」可能看似涵蓋了所有人工智慧編碼助理。實際上,它指的是業餘開發者或經驗不足的人工智慧使用者,試圖在不一定深入了解底層原理的情況下將想法實現。 「氛圍編碼指的是一種使用人工智慧進行編碼的方法,你幾乎閉上眼睛,完全不去看程式碼,只是要求人工智慧去為你建構東西,」他說。 Truell 將其比喻為在不知道地板下或電線佈線情況的情況下,就蓋起四面牆和屋頂來建造房屋。 他警告說,這種編碼方法對於希望快速模擬遊戲或網站的 AI 使用者來說可能很完美,但當涉及到更高級的程式設計時,事情有可能出錯。 「如果你閉上眼睛不看程式碼,讓人工智慧在搖搖欲墜的基礎上建構東西,當你加蓋一層又一層又一層又一層時,東西就會開始崩潰,」他說。 Cursor 有何不同——以及為何這很重要 相比之下,使用 Cursor,程式設計師可以將人工智慧直接嵌入到他們編寫程式碼的整合開發環境中。透過利用現有程式碼甚至整個程式庫的上下文,它通常可以預測下一行程式碼。該工具包含從多行自動完成到完整函式生成的所有功能。它還可以幫助程式設計師除錯並解釋錯誤。 儘管年僅 25 歲,Truell 對人工智慧編碼的看法具有相當的分量。他與其他三位麻省理工學院的畢業生在 2022 年將後來成為 Cursor 的專案創建出來。 自那時起,Cursor 已成為最受歡迎的編碼助理之一,根據 Bloomberg 報導,截至去年,其每日活躍用戶已超過 100 萬。根據 CNBC 的資料,自推出以來,該公司已達到 10 億美元的年化收入,並聚集了 300 名員工。 Cursor 在 2023 年從 OpenAI 的 Startup Fund 獲得了第一筆 800 萬美元的投資。隨後,它又從一些矽谷最大的風險投資公司,包括 Andreessen Horowitz,籌集了更多資金。2025 年,該公司以 293 億美元的投後估值完成了一輪 23 億美元的融資。最後,截至本月,Bloomberg 報導稱,該公司據稱正在進行一輪融資,其估值將達到約 500 億美元。 Truell 表示,雖然氛圍編碼者可能像是在盲目飛行,但 Cursor 編碼助理卻能兩全其美,幫助其專業客戶深入探究程式碼的細節。 「但在那些你想要退後一步,要求人工智慧執行端到端任務的地方,你也可以這樣做,」他說。 此故事的一個版本最初於 2025 年 12 月 25 日發表在 .com 上。 更多人工智慧相關報導: 特朗普點名祖克柏、黃仁勳、艾里森加入科技顧問委員會——但排除馬斯克和奧特曼 華爾街確信人工智慧將殺死 SaaS。歷史和經濟學則另有說法 Cursor 的十字路口:一家 300 億美元人工智慧新創公司的迅速崛起與極不確定的未來 本文由第三方廠商內容提供者提供。SeaPRwire (https://www.seaprwire.com/)對此不作任何保證或陳述。 分類: 頭條新聞,日常新聞 SeaPRwire為公司和機構提供全球新聞稿發佈,覆蓋超過6,500個媒體庫、86,000名編輯和記者,以及350萬以上終端桌面和手機App。SeaPRwire支持英、日、德、韓、法、俄、印尼、馬來、越南、中文等多種語言新聞稿發佈。

Peter & Sons Launches in Ontario with Ellipse Entertainment

(AsiaGameHub) -   Forward-thinking iGaming studio Peter & Sons has expanded its footprint in the Canadian market by rolling out its full game portfolio in partnership with Ellipse Entertainment, a fully licensed operator based in Ontario. Ellipse Entertainment operates in compliance with the province's regulated gaming framework, and offers players access to its flagship platform HighFlyerCasino.com. The website pairs a wide-ranging collection of casino titles with a secure, smooth, fully regulation-aligned gaming experience that is custom made specifically for players in the Ontario market. Ontario has quickly emerged as one of the most progressive regulated iGaming jurisdictions across North America. Players throughout the province can now access a curated selection of Peter & Sons titles via HighFlyerCasino.com, bringing the studio's unique game worlds and gameplay mechanics to a growing community of Canadian players. Widely recognized for its catalogue of indie-inspired creations, quirky characters, and carefully crafted game worlds, Peter & Sons continues to break new ground in slot design and interactive entertainment. By joining forces with Ellipse Entertainment, a platform dedicated to delivering premium gaming experiences within a trusted regulatory environment, the studio is looking forward to building a long-term collaborative partnership in the Ontario market. Yann Bautista, Peter & Sons Founder and Commercial Director, said: “We are thrilled to launch our game portfolio with Ellipse Entertainment and bring our titles to players in Ontario. This region has quickly cemented its status as a key regulated market in North America, and HighFlyerCasino.com offers a robust platform for introducing our one-of-a-kind games to Canadian audiences.” Larry Galansky, founder of Ellipse Entertainment added: “We are glad to welcome Peter & Sons to our platform as we continue expanding the entertainment options available to our players. Their games are known for their distinct artistic style and immersive gameplay, and we are confident they will strike a chord with our user base.” This article is provided by a third-party. AsiaGameHub (https://asiagamehub.com/) makes no warranties regarding its content. AsiaGameHub delivers targeted distribution for iGaming, Casino, and eSports, connecting 3,000+ premium Asian media outlets and 80,000+ specialized influencers across ASEAN.

VeliTech debuts in Brazil at BiS SiGMA South America 2026

(AsiaGameHub) -   VeliTech is poised to make its inaugural appearance in Brazil at Stand i156 during BiS SiGMA South America 2026, which will be held in São Paulo from 6–9 April. The team is arriving with a double awards shortlist and a casino content offering crafted to attract attention. The company has been shortlisted in two key categories: Best Platform for VeliTech Best Gaming Experience for VeliPlay This recognition highlights two robust components of the VeliTech ecosystem. VeliTech has been shortlisted for the strength of its proven iGaming core platform, while VeliPlay is being acknowledged for the fast-paced, high-energy gameplay experience delivered via its crash and instant games. For its Brazil debut, VeliTech is placing casino content at the forefront. Taking center stage is VeliPlay, whose collection of crash and instant games is designed for speed, immersion, and repeat play. The lineup is further bolstered by Heaven of 7, the slot games provider within the VeliTech group, renowned for visually appealing titles and entertaining mechanics. Both studios have recently expanded their portfolios with new releases, including Pinball Rush from VeliPlay and Coin Up: Rise from Heaven of 7. Completing the showcase is VeliGames, VeliTech’s aggregation platform, recently recognized as the Industry Rising Star by SiGMA. With a single integration, it offers a broad content portfolio and robust back-office capabilities for operators. Together, VeliPlay, Heaven of 7, and VeliGames form a casino proposition aimed at helping operators differentiate themselves, combining adrenaline-fueled crash and instant titles, engaging slot entertainment, and aggregation technology that ensures content delivery is straightforward, scalable, and commercially effective. Mats Lundin, Chief Sales Officer at VeliTech said “Brazil is currently one of the most dynamic markets in iGaming, so making our debut at BiS SiGMA South America is a significant milestone for us. We’re heading to São Paulo with a content lineup designed to leave an impression, from fast-paced crash and instant games to engaging slots, all supported by the power of VeliGames aggregation. Being shortlisted for both Best Gaming Experience and Best Platform ahead of our first event in Brazil makes this milestone even more thrilling.” Visitors can meet the VeliTech team at Stand i156 to discover how connected technology and high-performing content can collaborate to develop a more robust casino offering for iGaming brands. This article is provided by a third-party. AsiaGameHub (https://asiagamehub.com/) makes no warranties regarding its content. AsiaGameHub delivers targeted distribution for iGaming, Casino, and eSports, connecting 3,000+ premium Asian media outlets and 80,000+ specialized influencers across ASEAN.

Eisai and Nuvation Bio Announce Marketing Authorisation Application for Taletrectinib for the Treatment of Advanced ROS1-Positive Non-Small Cell Lung Cancer Validated by the European Medicines Agency

TOKYO and NEW YORK, NY., Mar 27, 2026 - (JCN Newswire via SeaPRwire.com) - Eisai Co., Ltd. (Headquarters: Tokyo, CEO: Haruo Naito, “Eisai”), a human-centered global leading research-based pharmaceutical company working in the neurology and oncology therapeutic areas, and Nuvation Bio Inc. (NYSE: NUVB, Corporate Headquarters: New York, NY, CEO: David Hung, M.D., “Nuvation Bio”), a global oncology company focused on tackling some of the toughest challenges in cancer treatment, today announced that the European Medicines Agency (EMA) has validated the Marketing Authorisation Application (MAA) for taletrectinib for the treatment of advanced ROS1-positive (ROS1+) non-small cell lung cancer (NSCLC). The filing will follow a standard review timeline.Taletrectinib (marketed as IBTROZI® in the U.S. and Japan) is a highly selective, next-generation oral treatment for patients living with advanced ROS1+ NSCLC.1 In January 2026, Eisai and Nuvation Bio announced they had entered into an exclusive licensing and collaboration agreement in Europe and additional countries* outside the U.S., China and Japan to extend the global reach of taletrectinib. Following this filing to the EMA, additional filings are planned for the U.K., Canada and other regions included in Eisai’s licensed territories.Across Europe, nearly 400,000 people are diagnosed with lung cancer each year with NSCLC accounting for 80% of cases.2,3 It is estimated that approximately 2% of patients with NSCLC have ROS1+ disease.4,5“The validation of the MAA is a significant moment for patients in Europe with ROS1+ NSCLC,” said Terushige Iike, Chief Business Officer of Eisai Co., Ltd. “With its efficacy and safety profile, we believe taletrectinib has the potential to become a standard of care therapy for the thousands of patients living with this aggressive disease in Europe. We look forward to working closely with the EMA during the review process with the goal of making this treatment available to appropriate patients who urgently need targeted options.”The application is based on data from the two pivotal Phase 2 clinical studies, TRUST-I and TRUST-II, evaluating taletrectinib in patients globally.6,7 Results from a pooled analysis of the TRUST clinical program were published in the Journal of Clinical Oncology in April 20258, and Nuvation Bio anticipates near-term disclosure of updated data reflecting even longer patient follow-up, further building on the depth and durability of responses observed to date. Additionally, given the comprehensive nature of the taletrectinib clinical dataset and based on favorable feedback received at a pre-submission meeting with the CHMP Rapporteur and Co-Rapporteur, the accepted MAA will be considered to support full approval.“Having seen the meaningful impact taletrectinib has already made for patients with ROS1+ NSCLC in the U.S., China and Japan, we are thrilled to partner with Eisai and have an accepted MAA for review in Europe,” said David Hung, M.D., Founder, President and Chief Executive Officer of Nuvation Bio. “This accepted filing represents an important milestone in our global development strategy and brings us one step closer to delivering this highly selective, next-generation oral therapy to more patients who need it in Europe and around the world.”In June 2025, the U.S. Food and Drug Administration (FDA) granted full approval to taletrectinib for the treatment of locally advanced or metastatic ROS1+ NSCLC across lines of therapy, following a Priority Review and double Breakthrough Therapy designations. Taletrectinib is also approved for patients with advanced ROS1+ NSCLC in Japan, where it is marketed by Nippon Kayaku, and in China, where it is marketed by Innovent Biologics under the brand name DOVBLERON®.* Eisai’s licensed territories: Europe, the Middle East, North Africa, Russia, Turkey, Canada, Australia, New Zealand, Singapore, the Philippines, Indonesia, Thailand, Malaysia, Vietnam and IndiaAbout ROS1+ NSCLCEach year, more than one million people globally are diagnosed with non-small cell lung cancer (NSCLC), the most common form of lung cancer.9 It is estimated that approximately 2% of patients with NSCLC have ROS1+ disease.4,5 About 35% of patients newly diagnosed with metastatic ROS1+ NSCLC have tumors that have spread to their brain.10 The brain is also the most common site of disease progression, with about 50% of previously treated patients developing central nervous system (CNS) metastases.10,11About TaletrectinibTaletrectinib is an oral, potent, CNS-active, selective, next-generation ROS1 inhibitor therapy. On June 11, 2025, following Priority Review and Breakthrough Therapy designations for both TKI-naive and TKI-pretreated disease, the U.S. Food and Drug Administration (FDA) approved taletrectinib for the treatment of adult patients with locally advanced or metastatic ROS1+ NSCLC. Learn more about taletrectinib in the U.S. at IBTROZI.com. 1About the TRUST Clinical ProgramThe TRUST clinical program comprises three registrational studies evaluating the safety and efficacy of taletrectinib. TRUST-I (NCT04395677) and TRUST-II (NCT04919811) are Phase 2 single-arm studies evaluating taletrectinib for the treatment of adults with advanced ROS1+ NSCLC in China (N=173) and globally (N=189), respectively. The primary endpoint of both studies is confirmed objective response rate (cORR) as assessed by an independent review committee. TRUST-IV (NCT07154706) is a Phase 3 placebo-controlled study evaluating taletrectinib for the adjuvant treatment of adults with resected early-stage ROS1+ NSCLC. The study will enroll approximately 180 patients in the U.S., Canada, Europe, Japan and China. The primary endpoint is disease-free survival as determined by investigator, and the primary completion date is estimated to be in 2030. Nuvation Bio is also sponsoring TRUST-III (NCT06564324), a confirmatory randomized Phase 3 study evaluating taletrectinib versus crizotinib in 138 patients in China with advanced ROS1+ NSCLC who have not previously received ROS1 TKIs.6,7About Eisai Co., Ltd.Eisai's Corporate Concept is "to give first thought to patients and people in the daily living domain, and to increase the benefits that health care provides." Under this Concept (also known as human health care (hhc) Concept), we aim to effectively achieve social good in the form of relieving anxiety over health and reducing health disparities. With a global network of R&D facilities, manufacturing sites and marketing subsidiaries, we strive to create and deliver innovative products to target diseases with high unmet medical needs, with a particular focus in our strategic areas of Neurology and Oncology.In addition, we demonstrate our commitment to the elimination of neglected tropical diseases (NTDs), which is a target (3.3) of the United Nations Sustainable Development Goals (SDGs), by working on various activities together with global partners.For more information about Eisai, please visit www.eisai.com (for global headquarters: Eisai Co., Ltd.), and connect with us on X, LinkedIn and Facebook. The website and social media channels are intended for audiences outside of the UK and Europe.About Nuvation BioNuvation Bio is a global oncology company focused on tackling some of the toughest challenges in cancer treatment with the goal of developing therapies that create a profound, positive impact on patients’ lives. Our diverse pipeline includes taletrectinib (IBTROZI®), a next-generation ROS1 inhibitor; safusidenib, a brain-penetrant IDH1 inhibitor; and an innovative drug-drug conjugate (DDC) program.Nuvation Bio was founded in 2018 by biopharma industry veteran David Hung, M.D., who previously founded Medivation, Inc., which brought to patients one of the world’s leading prostate cancer medicines. Nuvation Bio has offices in New York, San Francisco, Boston, and Shanghai. For more information, visit www.nuvationbio.com or follow the company on LinkedIn and X (@nuvationbioinc).U.S. IndicationIBTROZI is indicated for the treatment of adult patients with locally advanced or metastatic ROS1+ nonsmall cell lung cancer (NSCLC).IMPORTANT SAFETY INFORMATION FOR IBTROZI® (taletrectinib)1WARNINGS AND PRECAUTIONSHepatotoxicity: Hepatotoxicity, including drug-induced liver injury and fatal adverse reactions, can occur. 88% of patients experienced increased AST, including 10% Grade 3/4. 85% of patients experienced increased ALT, including 13% Grade 3/4. Fatal liver events occurred in 0.6% of patients. Median time to first onset of AST or ALT elevation was 15 days (range: 3 days to 20.8 months).Increased AST or ALT each led to dose interruption in 7% of patients and dose reduction in 5% and 9% of patients, respectively. Permanent discontinuation was caused by increased AST, ALT, or bilirubin each in 0.3% and by hepatotoxicity in 0.6% of patients.Concurrent elevations in AST or ALT ≥3 times the ULN and total bilirubin ≥2 times the ULN, with normal alkaline phosphatase, occurred in 0.6% of patients.Interstitial Lung Disease (ILD)/Pneumonitis: Severe, life-threatening, or fatal ILD or pneumonitis can occur. ILD/pneumonitis occurred in 2.3% of patients, including 1.1% Grade 3/4. One fatal ILD case occurred at the 400 mg daily dose. Median time to first onset of ILD/pneumonitis was 3.8 months (range: 12 days to 11.8 months).ILD/pneumonitis led to dose interruption in 1.1% of patients, dose reduction in 0.6% of patients, and permanent discontinuation in 0.6% of patients.QTc Interval Prolongation: QTc interval prolongation can occur, which can increase the risk for ventricular tachyarrhythmias (e.g., torsades de pointes) or sudden death. IBTROZI prolongs the QTc interval in a concentration-dependent manner.In patients who received IBTROZI and underwent at least one post baseline ECG, QTcF increase of >60 msec compared to baseline and QTcF >500 msec occurred in 13% and 2.6% of patients, respectively. 3.4% of patients experienced Grade ≥3. Median time from first dose of IBTROZI to onset of ECG QT prolongation was 22 days (range: 1 day to 38.7 months). Dose interruption and dose reduction each occurred in 2.8% of patients.Significant QTc interval prolongation may occur when IBTROZI is taken with food, strong and moderate CYP3A inhibitors, and/or drugs with a known potential to prolong QTc. Administer IBTROZI on an empty stomach. Avoid concomitant use with strong and moderate CYP3A inhibitors and/or drugs with a known potential to prolong QTc.Hyperuricemia: Hyperuricemia can occur and was reported in 14% of patients, with 16% of these requiring urate-lowering medication without pre-existing gout or hyperuricemia. 0.3% of patients experienced Grade ≥3. Median time to first onset was 2.1 months (range: 7 days to 35.8 months). Dose interruption occurred in 0.3% of patients.Myalgia with Creatine Phosphokinase (CPK) Elevation: Myalgia with or without CPK elevation can occur. Myalgia occurred in 10% of patients. Median time to first onset was 11 days (range: 2 days to 10 months).Concurrent myalgia with increased CPK within a 7-day time period occurred in 0.9% of patients. Dose interruption occurred in 0.3% of patients with myalgia and concurrent CPK elevation.Skeletal Fractures: IBTROZI can increase the risk of fractures. ROS1 inhibitors as a class have been associated with skeletal fractures. 3.4% of patients experienced fractures, including 1.4% Grade 3. Some fractures occurred in the setting of a fall or other predisposing factors. Median time to first onset of fracture was 10.7 months (range: 26 days to 29.1 months). Dose interruption occurred in 0.3% of patients.Embryo-Fetal Toxicity: Based on literature, animal studies, and its mechanism of action, IBTROZI can cause fetal harm when administered to a pregnant woman.ADVERSE REACTIONSAmong patients who received IBTROZI, the most frequently reported adverse reactions (≥20%) were diarrhea (64%), nausea (47%), vomiting (43%), dizziness (22%), rash (22%), constipation (21%), and fatigue (20%).The most frequently reported Grade 3/4 laboratory abnormalities (≥5%) were increased ALT (13%), increased AST (10%), decreased neutrophils (5%), and increased creatine phosphokinase (5%).DRUG INTERACTIONSStrong and Moderate CYP3A Inhibitors/CYP3A Inducers and Drugs that Prolong the QTc Interval: Avoid concomitant use.Gastric Acid Reducing Agents: Avoid concomitant use with PPIs and H2 receptor antagonists. If an acid-reducing agent cannot be avoided, administer locally acting antacids at least 2 hours before or 2 hours after taking IBTROZI. OTHER CONSIDERATIONSPregnancy: Please see important information in Warnings and Precautions under Embryo-Fetal Toxicity.Lactation: Advise women not to breastfeed during treatment and for 3 weeks after the last dose.Effect on Fertility: Based on findings in animals, IBTROZI may impair fertility in males and females. The effects on animal fertility were reversible.Pediatric Use: The safety and effectiveness of IBTROZI in pediatric patients has not been established.Photosensitivity: IBTROZI can cause photosensitivity. Advise patients to minimize sun exposure and to use sun protection, including broad-spectrum sunscreen, during treatment and for at least 5 days after discontinuation. Please see accompanying full U.S. Prescribing Information.(1) Nuvation Bio Inc. IBTROZI (taletrectinib) US prescribing information. Available at: https://ibtrozipi.com/IBTROZI_taletrectinib-prescribing-information.pdf. Last accessed: March 2026(2) Wood R, Taylor-Stokes G. Cost burden associated with advanced non-small cell lung cancer in Europe and influence of disease stage. Available here. Last accessed: March 2026(3) European Lung Foundation. Lung cancer. Available here. Last accessed: March 2026(4) Patil T, Smith DE, Bunn PA Jr, et al. The incidence of brain metastases in stage IV ROS1-rearranged non-small cell lung cancer and rate of central nervous system progression on crizotinib. J Thorac Oncol. 2018;13(11):1717-1726. doi:10.1016/j.jtho.2018.07.012.(5) Drilon A, Camidge DR, Lin JJ, et al. Repotrectinib in ROS1 fusion-positive non-small-cell lung cancer. N Engl J Med. 2024;390(2):118-131. doi:10.1056/NEJMoa2302299. (6) ClinicalTrials.gov. A Study of AB-106 in Advanced NSCLC With ROS1 Fusion (NCT04395677). Available at: https://clinicaltrials.gov/study/NCT04395677 . Last accessed: March 2026(7) ClinicalTrials.gov. A single-arm Phase 2 study of taletrectinib in advanced ROS1-positive NSCLC (NCT04919811). Available at: https://clinicaltrials.gov/study/NCT04919811 . Last accessed: March 2026(8) Pérol M, A., et al. Taletrectinib in ROS1-positive non-small cell lung cancer: TRUST. Journal of Clinical Oncology, 43(16), 1920–1929. https://doi.org/10.1200/JCO-25-00275(9) Global Data. Diagnosed incident cases of non-small cell lung cancer across 8MM to reach 1.46 million in 2032, forecasts GlobalData. Available here. Last accessed: March 2026(10) Patil T, Smith DE, Bunn PA Jr, et al. The incidence of brain metastases in stage IV ROS1-rearranged non-small cell lung cancer and rate of central nervous system progression on crizotinib. J Thorac Oncol. 2018;13(11):1717-1726. doi:10.1016/j.jtho.2018.07.012.(11) Drilon A, Camidge DR, Lin JJ, et al. Repotrectinib in ROS1 fusion-positive non-small-cell lung cancer. N Engl J Med. 2024;390(2):118-131.MEDIA CONTACTSEisai Co., Ltd.Public Relations DepartmentTEL: +81 (0)3-3817-5120Nuvation Bio Inc.Kaitlyn Nealymedia@nuvationbio.comINVESTOR CONTACTSEisai Co., Ltd.Investor Relations DepartmentTEL: +81 (0) 3-3817-5122Nuvation Bio Inc.JR DeVitair@nuvationbio.comForward-Looking Statements of Nuvation Bio Inc.Certain statements included in this press release that are not historical facts are forward-looking statements for purposes of the safe harbor provisions under the United States Private Securities Litigation Reform Act of 1995. Forward-looking statements are sometimes accompanied by words such as “believe,” “may,” “will,” “estimate,” “continue,” “anticipate,” “intend,” “expect,” “should,” “would,” “plan,” “predict,” “potential,” “seem,” “seek,” “future,” “outlook” and similar expressions that predict or indicate future events or trends or that are not statements of historical matters. These forward-looking statements include, but are not limited to, statements regarding taletrectinib’s therapeutic potential and the urgent need for new therapeutic options for patients with advanced ROS1+ NSCLC in Europe, our expectations that the MAA filing for taletrectinib will follow a standard review with a decision in 1H 2027 and be considered for full approval, plans for additional filings for the U.K., Canada and other regions included in Eisai’s licensed territories, and expectations for near-term disclosure of updated data. These statements are based on various assumptions, whether or not identified in this press release, and on the current expectations of the management team of Nuvation Bio and are not predictions of actual performance. These forward-looking statements are subject to a number of risks and uncertainties that may cause actual results to differ from those anticipated by the forward-looking statements, including but not limited to the challenges associated with conducting drug discovery and commercialization, and initiating or conducting clinical studies due to, among other things, difficulties or delays in the regulatory process, enrolling subjects or manufacturing or acquiring necessary products; the emergence or worsening of adverse events or other undesirable side effects; risks associated with preliminary and interim data, which may not be representative of more mature data; physician and patient behavior; and competitive developments. Risks and uncertainties facing Nuvation Bio are described more fully in its Form 10-K filed with the SEC on March 2, 2026 under the heading “Risk Factors,” and other documents that Nuvation Bio has filed or will file with the SEC. You are cautioned not to place undue reliance on the forward-looking statements, which speak only as of the date of this press release. Nuvation Bio disclaims any obligation or undertaking to update, supplement or revise any forward-looking statements contained in this press release. Copyright 2026 JCN Newswire via SeaPRwire.com. All rights reserved. www.jcnnewswire.com

Unlimited Super Free Spins in ELA’s Spring Release, Golden Bunny

(AsiaGameHub) -   ELA Games has unveiled Golden Bunny, a mid-volatility slot with an Easter theme. Ideal for the spring season, Golden Bunny combines a vibrant, hand-painted garden backdrop with streamlined, action-packed gameplay. The slot features a 5-reel, 3-row grid and uses a ‘Pays Anywhere’ system. At its core is an instant-reward mechanism where Egg symbols break open to show immediate payouts. Game progression revolves around Golden Eggs. Landing these symbols activates the regular Free Spins, which add extra prizes to the reels. At the same time, the eggs are collected in an Egg Basket located above the reels. As the basket gains value and expands, players progress toward the game’s key feature: Super Free Spins. When the basket overflows, this non-stop bonus round begins. The distinction here is that Super Free Spins eliminate the usual spin limits, continuing until the player hits the MINI, MINOR, MAJOR, or GRAND jackpot—revealed by the player in an interactive 'pick one' game. Marharyta Yerina, Managing Director of ELA Games, shared thoughts on the new title: “Golden Bunny is our spring 2026 release, and we aimed to pair our adorable bunny and playful theme with gameplay that gives players a clear goal. The ‘what you see is what you win’ aspect of the instant Egg rewards keeps the action going, but the real highlight is the Super Free Spins. Knowing the feature won’t stop until a jackpot is won builds great anticipation.” Golden Bunny will launch on March 26, 2026. Game Stats: Grid: 5×3 Paylines: Pays Anywhere Volatility: Mid (3/5) RTP: 93.93% / 96.01% Min Bet: €0.10 Max Bet: €50 Max Win Cap: x2000 Max Exposure: 100,000 This article is provided by a third-party. AsiaGameHub (https://asiagamehub.com/) makes no warranties regarding its content. AsiaGameHub delivers targeted distribution for iGaming, Casino, and eSports, connecting 3,000+ premium Asian media outlets and 80,000+ specialized influencers across ASEAN.

美麗田園2025年報重磅發佈!經調淨利潤大增41% 現金牛實力凸顯

香港, 2026年3月27日 - (亞太商訊 via SeaPRwire.com) - 3月27日,美麗田園醫療健康(02373.HK)正式發佈2025年度業績報告。年內,集團營收、利潤、現金流全方位高質量增長,以硬核業績凸顯行業龍頭的強增長韌性。集團盈利能力實現跨越式躍升。2025年,美麗田園集團總收入30億元,同比增長16.7%;毛利率提升至49.1%,同比提高2.8個百分點;經調淨利潤攀升至3.8億元,同比大幅增長41.0%,經調整淨利率達12.7%,提高2.2個百分點,盈利水平邁上新台階。公司持續顯現「現金牛屬性」。2025年集團經營活動產生的現金流量淨額達10.0億元,同比大幅增長25.4%;截至2025年12月31日,集團現金及類現金項目金額合計高達25.9億元,同比淨增41.6%,充沛且強勁的現金流為集團戰略投資與股東回報提供充足動能。這份營收與利潤大幅增長的亮眼業績,是集團「內生增長+外延並購」商業模式的成功體現,也是集團精益管理、提質增效及數智化賦能帶動整體效率提升的有力印證。「雙美+雙保健」模式賦能,盈利能力全面上揚作為核心基石業務,集團美與健康板塊逆勢高增,全年交出令市場矚目的亮眼答卷。2025年,美容和保健服務收入16.6億元,同比增長14.9%;毛利率提升1.2個百分點至41.9%;直營門店客流達172.4萬人次,同比增長23.2%;直營活躍會員增至14.6萬名,同比增長11.8%,直營活躍會員年均消費金額9738元,同比提升320元。直營活躍會員規模與年均消費實現雙增長。業績高質量增長的同時,集團錨定長期發展戰略。2025年,我們正式發佈超級供應鏈戰略,全面升級產品創研體系。未來,產品創研方式將全新拓展為全球精選、國際品牌合作、國際頂尖實驗室聯合研發三大模式並進,在傳承卓越品質的同時,注入創新動能。2026年2月,我們重磅宣佈與全球知名護膚品牌資生堂達成重磅戰略合作,在品牌影響力、服務體驗、科研共創等多維度深度攜手,開啟美與健康領域合作的新篇章。消費醫療兼具醫療價值屬性與消費彈性,是承載長期結構性機遇的優質賽道。美麗田園集團深耕消費醫療賽道,圍繞高端女性美與健康的核心醫療需求深度延伸佈局。過去16年,我們從0到1自建消費醫療能力,目前全國落地38家消費醫療機構,形成規模化佈局。2025年,消費醫療板塊整體收入13.4億,同比增長18.9%,占收入比例達到44.8%,成為重要的增長驅動力。具體來看,2025年集團醫療美容服務-秀可兒醫美逆勢增長,實現收入10.2億元,同比增長9.6%,毛利率大幅提升3.6個百分點至55.9%;客流10.2萬人次,同比增長13.1%,活躍會員攀升至3.6萬名,同比增長7.7%;活躍會員年均消費27,862元,同比增加490元。為進一步破局行業競爭、打造差異化核心優勢,秀可兒醫美精准錨定「專研抗衰」賽道,以「專家、專研、專注原生美」為品牌定位。2026年3月,Cellcare秀可兒品牌舉辦「專研抗衰」品牌升級發佈會,圍繞不同年齡層女性抗衰需求,打造 「初老抗衰、凍齡抗衰、逆齡抗衰」 的全週期產品藍圖,正式開啟秀可兒專研抗衰新時代。亞健康醫療服務--研源醫療作為集團增值業務迎來爆發式增長。2025年,研源醫療收入3.3億元,同比大增62.2%,收入佔比首次突破10%,成為集團業績增長的重要引擎;毛利率升至64.3%,同比提升6.1個百分點;客流量3.7萬人次,同比增長35.7%,活躍會員人數同比大增37.9%,活躍會員年平均消費28,032元,同比增加6287元。2025年,研源醫療旗下功能醫學板塊收入同比增長101%。在AI浪潮之下,我們將通過自研AI模型,深度融合精准檢測數據、專家診療路徑與臨床案例,實現「千人千面」的個性化診療方案與7x24全天候服務,以科技賦能醫療服務全面升級。研源醫療旗下女性特護板塊收入增長64%。我們將持續拓展服務版圖,構建「預防-治療-抗衰」女性健康醫療服務。並購整合戰略升級,以共贏之姿賦能行業發展中國「美與健康」市場坐擁萬億賽道規模,機遇與挑戰並存,合作共贏已經成為行業發展的必然趨勢。美麗田園主動投身行業整合進程,將投資並購上升為集團級核心戰略,以開放共贏的姿態攜手行業夥伴,共同推動美業高質量發展。2026年3月,集團重磅舉辦「尋找100位美業同行者」戰略投資暨行業賦能發佈會,宣佈將聚焦中國20個高線城市的美與健康服務機構,誠邀更多行業夥伴融入美麗田園生態體系,依託持續打磨精進的商業系統為行業夥伴提供全方位賦能提效,實現共生共贏。這一戰略佈局的底氣,源自集團過往逾30多起收並購項目中所積澱的深厚實戰經驗與可複製的整合方法論。2024年,集團完成對中國美容行業市占率第二大品牌奈瑞兒的收購,並通過系統化、精細化整合,實現奈瑞兒收入和利潤雙提升。2025年,奈瑞兒單店收入從收購前的575萬提升至810萬、經調淨利率從6.5%大幅提升至10.5%,以亮眼的數據印證了美麗田園強大的並購整合能力,更形成了一套可複製、可延展的行業整合成功範式。2025年10月,美麗田園集團宣佈以12.5億元人民幣全資收購行業第三大品牌思妍麗100%股權。伴隨著思妍麗於2026年1月正式併入集團報表,我們將複製奈瑞兒成功經驗,充分發揮自身模式優勢和平台能力,為業績增長注入新動能。至此,三大品牌齊聚美麗田園集團麾下,市場佔有率實現跨越式提升,中國美容行業競爭格局重塑。重磅打造商業系統,構建企業可持續增長核心壁壘33 年深耕,美麗田園集團從美容服務逐步延伸至消費醫療,已成功建成面向高線城市女性的美與健康綜合服務平台。2025年,集團重磅打造美麗田園商業系統,從多維度構建企業可持續增長模式,為長遠發展築牢體系根基。客戶價值成長系統。通過精細化客戶運營體系,我們構建起覆蓋推廣、獲客、轉化、會員留存、價值提升、複購、裂變的全鏈路運營閉環,為客戶持續創造長期價值。強平台+多品牌系統。我們構建了「強平台+多品牌事業部」協同的組織體系,支撐多品牌、多業務高效聯動與協同發展。前台事業部聚焦市場與客戶,靈活作戰、快速響應;平台沉澱能力、輸出標準,讓協同貫穿業務全流程,有效提升運營效率與業務延展性,為多品牌有序擴張提供堅實組織支撐。並購價值成長系統。我們構建了「投資+整合+成長」全週期並購價值成長體系,通過持續積累行業獨特的投資數據、成熟的投前模型、精進的投中整合,全面提升投後價值,形成成熟的並購與賦能機制,可適配不同規模、不同業務的優質標的,真正實現「並購即融合、融合即增值」。數智化與AI系統。集團將構建數智化驅動的管理體系,深度賦能美麗田園商業系統,讓體系能力可落地、可複製、可迭代,成為集團穿越經濟週期、持續引領行業發展的堅實支柱。資本市場價值提升,持續釋放長期投資價值2025年3月,集團正式發佈三大舉措,圍繞股東結構優化、高分紅比例及管理層激勵,持續向資本市場釋放長期投資價值。股東結構優化方面,2025 年 8 月,原PE股東中信產業基金正式退出主要股東行列,同步引入優質長期戰略投資者,股東結構進一步夯實。分紅方面,2026年董事會提議延續高分紅比例,將2025年歸母淨利潤的50%用於分紅,派發每股0.72港元,同比增長38.5%,以真金白銀的回報持續強化股東回報,彰顯企業對自身發展的堅定信心。管理層激勵方面,2025年,集團將未來三年收入及利潤目標與股權激勵深度綁定,首年業績目標已超額達成,激勵機制的有效性得到充分驗證。在此基礎上,公司進一步上調管理層股權激勵對應的三年業績目標,以更高標準統一公司與股東利益,在釋放增長潛力的同時,為投資者創造長期穩定回報。2025 年 11 月,公司成功納入 MSCI 全球小型股指數,進一步進入全球被動及主動型基金視野,吸引更廣泛的國際投資者關注。未來展望:三大超級戰略領航,錨定長期高質量發展美麗田園集團的長期願景是成為中國美與健康的領航者。站在行業整合與品牌升級的新起點,2025年11月,美麗田園正式發佈超級品牌、超級連鎖、超級數字化三大戰略,為未來高質量發展指明方向,擘畫長期發展藍圖。超級品牌,構建美與健康品牌矩陣。我們持續升級專業實力,打造超越客戶期待的體驗,重塑美容行業價值新空間。同時,積極參與並推動行業標準制定,將美麗田園的高標準上升為行業共識,提升消費者信任與品牌價值。超級連鎖,我們將發揮「雙美+雙保健」商業模式優勢,通過內生增長與外延並購雙輪驅動戰略帶動公司價值躍升。我們致力於打造20個收入過億的核心城市,同時構建自有供應鏈能力,融合全球精選與聯合專研,為中國高線城市女性提供兼具專業性、個性化、高品質的美容和消費醫療產品與服務。超級數字化,我們致力於打造數智化與AI系統基礎建設,構建數智化驅動的企業管理體系,打造數智引領的美與健康服務連鎖標杆企業。結語未來,美麗田園將繼續堅守「以客戶為中心」的初心,依託「美麗田園商業系統」,以「三大超級戰略」為指引,在不斷滿足高線城市女性對美與健康的多元需求的同時實現立體增長,推動中國美與健康行業的高質量發展。 Copyright 2026 亞太商訊 via SeaPRwire.com. All rights reserved. www.acnnewswire.com

梅琳達· francês·蓋茨處理工作衝突有著原則:發言前等待 48 小時

(SeaPRwire) -   Melinda French Gates 分享了她處理職場衝突的秘訣。她選擇延後處理。 「如果我對你所做的工作不滿意,你會在 48 小時內收到我的消息,」French Gates 本週在接受 Bloomberg Business 的 Leaders with Francine Lacqua 播客採訪時說。「我不會馬上告訴你,因為我需要時間仔細思考。」 「如果我對某件事感到生氣,[我會這樣做來讓自己冷靜下來],」她補充說。「這是我的問題。」 她解釋說,這種做法與其說是為了壓制批評,不如說是為了以誠實、正直和恩典的方式提出批評。48 小時的時限也有其深意。如果時間過去了而沒有收到任何回饋,那就意味著員工做得很好。 「如果他們過了 48 小時的期限,他們就可以放心,他們的工作做得很好,」她說。「你不會在績效評估時遇到驚喜。」 這位億萬富翁慈善家數十年來一直在磨練這種做法。她從 2000 年到 2024 年一直擔任 Bill & Melinda Gates Foundation(世界上最大的私人慈善組織)的聯合主席,直到她於 2024 年卸任,這是在她與比爾·蓋茲離婚後約三年。 如今,French Gates 經營著自己的組織 Pivotal Ventures,這是一家她於 2015 年創立的投資和孵化公司,旨在促進美國女性和家庭的機會。作為與 Microsoft 創始人離婚協議的一部分,French Gates 獲得了 125 億美元,用於通過 Pivotal 進行慈善工作。她承諾在 2026 年之前每年額外捐贈 10 億美元,以增強全球女性的力量。 Melinda French Gates 的領導方法及其與其他高管的比較 Bloomberg 的 Lacqua 將 French Gates 的回饋方法稱為她的「領導超級能力」,這需要情緒紀律和坦誠。 「清晰就是善良,」French Gates 回應道,「因為我提供回饋是為了讓他們能夠真正成長並變得更好。」 French Gates 還將她的 48 小時回饋原則描述為在保持個人正直的同時,維護對方的尊嚴:「在開口之前,要恩典、周到。」 她的哲學與一些高管更具攻擊性的回饋文化相衝突。例如,Ray Dalio 將他的公司文化建立在他所謂的「徹底透明」之上,這是一種員工在各個層級都被期望提供未經篩選的實時批評的系統,幾乎所有會議都會被記錄下來以供事後分析。 Dalio 告訴 Business Insider:「如果你開始在智力上意識到,彼此之間真正誠實是一件值得珍惜的事情。」「這將建立信任。」 「有很多信任在其中,」創辦了全球最大對沖基金公司 Bridgewater Associates 的 Dalio 補充道。他甚至回憶起 Business Insider 曾有一次,一名初級員工給他發了一封電子郵件,將他在會議中的表現評為「D-」,因為他組織混亂。 因此,雖然 Dalio 偏愛即時和直白的批評,但 French Gates 則選擇更多的反思時間和尊重的語氣。 Microsoft 首席執行官 Satya Nadella 採取了略有不同的方法。當他接任 Microsoft 的領導職務時,他推動將「無所不知」的文化轉變為「無所不學」的文化——一種植根於謙遜、好奇心和心理安全感的文化。這是受到美國心理學家 Carol Dweck 的啟發,她以在動機和思維模式方面的研究而聞名。 Nadella 在 2016 年接受 Bloomberg 採訪時說:「如果你有兩個人,一個是無所不學的人,另一個是無所不知的人,那麼無所不學的人最終會勝過無所不知的人,即使他們最初的內在能力較差。」 儘管如此,French Gates 清楚地表示,她並不迴避困難的對話。 「我不介意衝突,」她告訴 Bloomberg。「我學會了以一種對我來說能保持我正直的方式來處理它。」本文由第三方廠商內容提供者提供。SeaPRwire (https://www.seaprwire.com/)對此不作任何保證或陳述。 分類: 頭條新聞,日常新聞 SeaPRwire為公司和機構提供全球新聞稿發佈,覆蓋超過6,500個媒體庫、86,000名編輯和記者,以及350萬以上終端桌面和手機App。SeaPRwire支持英、日、德、韓、法、俄、印尼、馬來、越南、中文等多種語言新聞稿發佈。

New “L00 Series” Train for the Seibu Railway’s Yamaguchi Line Begins Commercial Operation

The Frst New Leo Liner "L00 Series"TOKYO, Mar 27, 2026 - (JCN Newswire via SeaPRwire.com) - Mitsubishi Heavy Industries, Ltd. (MHI) has completed delivery of the first trainsets L00 Series ("Leo-kei") trains (4 cars per trainset, total 12 cars) ordered by Seibu Railway Co., Ltd. for its Yamaguchi Line, an automated guideway transit (AGT) system. Commercial operation of the first train began on March 27th. That same day, Seibu Railway held a commemorative ceremony for the start of commercial operation, attended by Tokorozawa City Mayor Masatoshi Onozuka and Higashimurayama City Mayor Takashi Watanabe.The new L00 Series are being manufactured at MHI's Mihara Machinery Works in Hiroshima Prefecture, and are scheduled to be delivered sequentially by FY2027. The seating arrangement has been changed from the bench seats used in the existing 8500 Series vehicles to longitudinal seats to increase transport capacity to BELLUNA DOME baseball stadium and Seibuen Amusement Park. To meet diverse passenger needs, wheelchair spaces, children's seats, and in-car information displays have been installed to enhance convenience.In addition, the new trains incorporate many unique specifications designed by MHI especially for AGT system vehicles, including aluminum bodyshells, the MHI bogie,(1), a ceiling duct air conditioning system,(2) and A-MVCS (Advanced Mitsubishi Vehicle Control System). The A-MVCS in particular, in addition to the vehicle control function, has monitoring and commissioning functions for each piece of on-board equipment, allowing it to flexibly meet the needs of railway operators.Further, a large glass window has been installed in the partition wall between the driver's cab and the children's seat, allowing children to enjoy the view from the front window and driver's seat, enhancing the sense of excitement for passengers.This AGT system utilizes rubber tires for a smooth ride and low noise. In addition, as a type of clean mobility with low CO2 emissions, the system has a reduced environmental impact, supporting the realization of a decarbonized and energy-efficient world. The adoption of vehicles that combine excellent design and environmental performance also enhances the impression of the surrounding facilities.Going forward, MHI Group will continue to strive for technological innovation, and through services that safely and comfortably transport people and goods, contribute to the development of public transport that supports the lives of people around the world.(1) A bogie developed by MHI for AGT systems. It is compatible with general rubber tire operation for AGTs.(2) A system that directs air through ducts behind the ceiling to provide air conditioning.About MHI GroupMitsubishi Heavy Industries (MHI) Group is one of the world’s leading industrial groups, spanning energy, smart infrastructure, industrial machinery, aerospace and defense. MHI Group combines cutting-edge technology with deep experience to deliver innovative, integrated solutions that help to realize a carbon neutral world, improve the quality of life and ensure a safer world. For more information, please visit www.mhi.com or follow our insights and stories on spectra.mhi.com Copyright 2026 JCN Newswire via SeaPRwire.com. All rights reserved. www.jcnnewswire.com

Modern Dental Group Announces 2025 Annual Results, Net Profit Surges 47.7% on Digitalization-Driven Operational Efficiency Gains

RESULTS HIGHLIGHTS:- The Revenue for the year ended 31 December 2025 was approximately HK$3,736.5 million, representing an increase of approximately 11.1% as compared with the same period last year.- The Gross Profit Margin for the year ended 31 December 2025 was approximately 55.8%; the gross profit was approximately HK$2,085.0 million, representing an increase of approximately 15.9% as compared with the same period last year.- The Group’s EBITDA for the year ended 31 December 2025 was approximately HK$938.1 million, representing an increase of approximately 32.4% as compared with the same period last year.- The Group’s net profit for the year ended 31 December 2025 was approximately HK$601.2 million, representing an increase of approximately 47.7% as compared with the same period last year.- Basic earnings per share for the year ended 31 December 2025 amounted to approximately HK63.7 cents, representing an increase of approximately 47.5% as compared with the same period last year.- The Board recommended the payment of a final dividend of HK15.0 cents per ordinary share for the year ended 31 December 2025.- For the year ended 31 December 2025, the Group recorded approximately 1,039,000 cases digital solution cases produced from the Group’s production facilities in Mainland China, Thailand and Vietnam, reflecting an increase of 32.7% as compared with the same period in 2024 as a result of our clients’ continued adoption of intra-oral scanners.HONG KONG, Mar 27, 2026 - (ACN Newswire via SeaPRwire.com) - 26 March 2026, Modern Dental Group Limited (“Modern Dental” or “the Group”, stock code: 03600.HK), a leading global dental prosthetic device provider, announces its annual results for the year ended 31 December 2025 (“the year”).During the year ended 31 December 2025, the Group’s multi-dimensional strategies and continuous enhancement of operational efficiency and productivity as supported by the ongoing trend of digitalization in the dental industry have resulted in the Group reporting record revenues, net profit and EBITDA numbers during this period. This occurred in a period of challenging macro-economic environment with general softness in demand for dental procedures and trade war uncertainties. The Group has been proactive in its approach to deal with the unprecedented international trade environment leveraging its international production facilities located in Thailand, Vietnam and Mainland China.The global digitalization trend continues to drive consolidation within the dental prosthetics industry, enabling the Group to further expand its market share. Our ongoing digital transformation initiatives are enhancing both customer and patient experiences while improving operational efficiency, further differentiating the Group from competitors and positioning us to outperform industry peers. The Group’s underlying fundamentals remain solid, and we are well positioned to capitalize on emerging opportunities going forward.European BusinessesDuring the year ended 31 December 2025, the European market recorded a revenue of approximately HK$1,887.0 million, representing an increase of approximately HK$268.0 million as compared with the year ended 31 December 2024. This geographic market accounted for 50.5% of the Group’s total revenue. The increase of revenue from the European market was mainly attributable to the increase in sales order volume driven by the launch of new products, such as digital dentures, and our state-of-the-art digital workflows.The Group has been the frontrunner to provide comprehensive digital solutions offerings, ranging from numerous minimal invasive and aesthetic prosthetic solutions to intra-oral scanners and clear aligners, and is well positioned to capture the opportunities arising from the accelerated digitalization trend of the dental industry. The Group continues to aggressively gain market share from international and domestic competitors through our established dental ecosystem solutions with a focus on education and digitalization, which is available within close proximity to our clients; effectively meeting our clients’ high expectations through our various onshore and offshore resources. The Group is committed and will continue to equip ourselves to provide the state-of-the-art digital solutions offerings to the dental community in the market.North American BusinessesDuring the year ended 31 December 2025, the North American market recorded a revenue of approximately HK$696.4 million, representing a decrease of approximately HK$55.7 million as compared with the year ended 31 December 2024. This geographic market accounted for approximately 18.6% of the Group’s total revenue.A significant portion of our business in the North America region comprises higher-end products manufactured domestically by MicroDental Laboratories, Inc. and its subsidiaries (“MicroDental Group”). While demand for discretionary cosmetic treatments remained soft throughout 2025, our centralized digital workflows and network-wide production oversight enabled us to deliver enhanced service quality and operational efficiencies to our North American customers.Our diversified supply bases in the US, China, Vietnam and Thailand continue to provide greater flexibility to navigate US tariff uncertainties — an advantage that sets us apart from competitors. Although digitalization of imported product lines drove growth in mass market cases, implementation of the US tariff in April 2025 introduced new uncertainties and contributed to a slow growth in sales for our import-focused business unit.Greater China BusinessesFor the year ended 31 December 2025, the Greater China market recorded a revenue of approximately HK$615.4 million, representing a decrease of approximately HK$46.8 million as compared with the year ended 31 December 2024. This geographic market accounted for approximately 16.5% of the Group’s total revenue.The Mainland China market faced headwinds from the volume-based procurement policies and a prolonged period of intense price competition and the situation started to stabilize in the second half of 2025. This also led to aggressive promotions for dental implant treatments by Mainland China dental clinics in Hong Kong (which experienced a notable decrease in patient visits in Hong Kong). The Group’s has deliberately pivoted away from low-margin segments and stay focused on serving mid- and high-value customers, ensuring long-term sustainable profitability of the Group’s business.The Group is optimistic in its mid/long-term outlook for this market in particular where the latest procurement-related government measures are expected to (i) standardize the pricing of dental prosthetics and develop price transparency, which would level the playing field; (ii) allow the Group’s leading brand name and reputation to be a key consideration for its client and customer; and (iii) have the Group benefit from its large production team and its ability to allocate resources efficiently according to the customer or client.Australian BusinessesFor the year ended 31 December 2025, the Australian market recorded a revenue of approximately HK$289.1 million, representing an increase of approximately HK$24.4 million as compared with the year ended 31 December 2024. This geographic market accounted for approximately 7.7% of the Group’s total revenue. The increase in revenue from Australia reflected a strong uptake of new digital products driven by the digitalization trend in dental industry and the revenue contribution from the acquisition of Digital Sleep which is partially offset by the depreciation of AUD against HK$ by 2.4% compared with the year ended 31 December 2024.Through our various brands, which offer onshore-and offshore-made products, at multiple price points ranging from economy and standard to premium/boutique, the Group is able to effectively penetrate the entire Australian market. We have invested in local production capacity to provide faster service to our customers, and to provide choices around where the products are made. The Group is one of the largest players in the Australian market and is a preferred supplier to the major corporate dental groups in the market.Other MarketsOther markets primarily include Thailand, Indian Ocean countries, Malaysia, Taiwan and Singapore. For the year ended 31 December 2025, these markets recorded a revenue of approximately HK$248.9 million, representing an increase of approximately HK$182.4 million as compared with the year ended 31 December 2024. This geographic market accounted for approximately 6.7% of the Group’s total revenue. The increase in revenue from Other markets was primarily driven by the revenue contribution from the newly acquired Hexa Ceram.Future Prospects and StrategiesThe global macroeconomic environment remains uncertain, with geopolitical tensions and potential tariff changes continuing to create headwinds. However, the Group’s geographically diversified production footprint and global distribution network position us strongly to navigate these challenges. Unlike many competitors reliant on single-country manufacturing, our operations across China, Vietnam and Thailand (including the newly acquired Hexa Ceram) provide superior resilience and flexibility. This strategy, combined with our ability to adapt quickly to local market conditions, enables the Group to mitigate risks and capitalize on opportunities across regions.The dental industry has continued to demonstrate remarkable resilience, underpinned by irreversible demographic trends, including aging populations and increasing awareness of oral health, which drive consistent long-term demand. Building on our record 2025 performance, the Group is well placed to sustain momentum and further strengthen its market leadership.Digitalization remains an irreversible industry trend that is accelerating consolidation of the dental prosthetics industry. We are at the forefront of this transformation, with digital solution cases now representing approximately 35–40% of total volume. Our centralized digital workflows, intra-oral scanner partnerships, proprietary solutions and global education centers have enhanced operational efficiency, reduced turnaround times and delivered superior customer experiences. These initiatives create high entry barriers and will continue to drive margin expansion and market share gains in the coming years.Following the successful integration of Hexa Ceram (Thailand’s largest dental laboratory, acquired in January 2025) and Digital Sleep Design (Proprietary nylon oral appliance to treat obstructive sleep apnea), our Southeast Asian presence and specialized capabilities have been significantly strengthened. This expansion, coupled with our diversified supply bases in the US, China, Vietnam, and Thailand, provides enhanced flexibility to address potential trade and geopolitical risks while supporting faster regional delivery.Looking ahead, the Group remains committed to reinforcing its worldwide leading position through a multi-dimensional approach. We will continue to pursue selective acquisitions, joint ventures and partnerships to expand and complement our product offerings, particularly in our high-growth clear aligner, Trioclear, while strengthening our distribution and sales networks. Ongoing investments in mass-scale production facilities, AI, automation, research and development, and digital innovation will drive efficiency gains and secure our position at the forefront of the industry.About Modern Dental GroupModern Dental Group Limited (Stock code: 03600.HK) is a leading global dental prosthetics provider, distributor and consultant with a focus on providing custom-made prostheses to customers in the growing prosthetics industry. Our product portfolio is broadly categorized into three product lines: fixed prosthetic devices, such as crowns and bridges; removable prosthetic devices, such as removable dentures; and other devices, such as orthodontic devices, sports guards, clear aligners, and anti-snoring devices. Modern Dental Group has a global portfolio of respected brands, including Labocast, Permadental and Elysee Dental in Western Europe, YZJ Dental in China, Modern Dental Lab in Hong Kong, Modern Dental USA and MicroDental in the United States, Modern Dental Pacific in Australia and New Zealand, Modern Dental SG in Singapore, Modern Dental TW in Taiwan, Apex Digital Dental in Malaysia and Hexa Ceram in Thailand. We have grown these brands by providing premium and consistent quality products and superior customer service. We have more than 80 service centers in over 28 countries and serve over 35,000 customers. Copyright 2026 ACN Newswire via SeaPRwire.com. All rights reserved. www.acnnewswire.com

iGaming Real Talk Establishes Media Collaboration with Centurion FC

(AsiaGameHub) -   iGaming Real Talk is thrilled to reveal a new media partnership with Centurion FC, bringing exclusive behind-the-scenes content and detailed coverage to the global iGaming community. This collaboration seamlessly bridges the worlds of elite MMA and iGaming, delivering impactful cross-industry content for both fans and industry leaders. Centurion FC 28: Progredior will take place on April 8, 2026, at the Transamerica Expo Center in São Paulo as a flagship event of the renowned SiGMA World Tour.Happening right in the middle of BiS SiGMA South America—where top leaders from gaming, technology, and entertainment come together—this gives iGaming professionals an excellent opportunity to enjoy high-energy MMA fights and connect with key industry players. CFC 28 will broadcast live on XSPORT, which averages 10 million daily users with a potential reach of 150 million across Brazil, alongside international partner RYZ Sports Network. iGaming, tech, and entertainment companies now have the chance to secure exclusive sponsorship packages for this high-visibility event. Packages include premium octagon branding, weigh-in activations, full digital campaigns on Facebook, Instagram, and YouTube, VIP hospitality, and fighter brand ambassador opportunities. This article is provided by a third-party. AsiaGameHub (https://asiagamehub.com/) makes no warranties regarding its content. AsiaGameHub delivers targeted distribution for iGaming, Casino, and eSports, connecting 3,000+ premium Asian media outlets and 80,000+ specialized influencers across ASEAN.