HONG KONG, Mar 26, 2026 - (ACN Newswire via SeaPRwire.com) – CALB (03931.HK) rolled its pioneering 'R46 cylindrical battery' system off the production line at the Chengdu factory on March 25, an aviation power battery set to power the XPENG ARIDGE X3-F Land Aircraft Carrier flying car. The recently unveiled R46 cylindrical battery technology boasts an energy density of 360 Wh/kg, the highest-density solid-liquid hybrid cylindrical battery in the industry. It achieves an exceptional balance between high safety, high power density and high energy density, meets aviation-grade safety standards, and will be equipped in several of ARIDGE's flying car models.The partnership between the two parties began in 2022, with CALB assisting ARIDGE in completing the world’s maiden flight of an electric vertical take-off and landing (eVTOL) flying car. Following rigorous validation, the reliability of CALB’s battery product has been fully verified. Building on this momentum, CALB assembled a team of top researchers to focus on the next-generation advanced R46 cylindrical battery system, tasked with addressing a range of scientific and technological challenges.Taking the lead in collaborating with leading institutions including ARIDGE, CALB has been awarded support by the National Key R&D Program Project, further positioning the technologies at the forefront of global innovation in intrinsic safety and high-specific-energy aviation power batteries. Consequently, the two parties signed a deepened strategic cooperation agreement in April 2025, establishing an exclusive supply relationship for next-generation models.From leading the National Key R&D Program focused on advanced R46 cylindrical battery system technology to achieving the mass production of flying car batteries, CALB is accelerating its expansion into forward-looking emerging sectors. The company's commercialization capability across diversified application scenarios continues to strengthen, opening new growth opportunities in the competition for next-generation energy technologies. CALB Group Co., Ltd. https://en.calb-tech.com/ [03931.HK] Copyright 2026 ACN Newswire via SeaPRwire.com. All rights reserved. www.acnnewswire.com

- 华堂宁(R)全年銷量超400萬盒，同比增長91%，銷售額達4.929億元，同比增長93%，公司全面自主商業化運營成效卓著。- 實現創紀錄盈利，稅前盈利達11.064億元；現金餘額穩健，截至年末達 10.923億元，為持續運營發展奠定堅實基礎。- 毛利率提升至56.9%，銷售開支占比從59.9%優化至33.6%，盈利能力顯著增強。- 华堂宁(R)原價續約新版醫保目錄，2026-2027年維持2025年的價格不變，臨床價值和創新價值再獲認可。- 隨著PTE獲批，中國市場獨佔權獲5年延期至2034年4月，商業確定性進一步提升。- 多格列艾汀（HYHOMSIS(R) ，華領片(R)）獲得香港地區上市批准，加速其面向東南亞的全球擴張進程。- 發佈多項真實世界證據，證實多格列艾汀治療優勢。- 持續拓展血糖穩態治療潛力，啟動多項全新的疾病首創新適應症研究，研究範圍涵蓋糖尿病預防、罕見病、輕度認知障礙及衰弱症領域。上海, 2026年3月27日 - (亞太商訊 via SeaPRwire.com) - 華領醫藥（「公司」，香港聯交所股份代號：2552）宣佈公司及其附屬公司截至2025年12月31日止年度（「報告期」）經審核的綜合業績。報告期內，公司核心產品、全球首創抗糖尿病新藥、葡萄糖激酶激活劑（GKA）华堂宁(R)（多格列艾汀片）實現全方位推進，公司自主商業化團隊於運營首年即實現高效組建和運轉，研發管線持續豐富，財務表現實現歷史性突破，成功邁入盈利新階段，為全球糖尿病治療領域的創新發展注入強勁動力。華領醫藥創始人、CEO陳力博士表示：「2025年是華領醫藥商業化運營中的意義非凡的一年。公司成功完成從研發驅動型組織向商業化驅動型組織的轉型，具備了全球首創新藥、血糖穩態調節劑华堂宁(R)的完全自主商業化運營能力。憑藉強勁的市場執行力與產品競爭力，相較於2024年將商業化業務委託給營銷合作夥伴的階段，公司的銷量與營收實現了近三位數的增長。與此同時，通過推動多格列艾汀在香港的註冊工作，公司在全球市場拓展方面取得了關鍵性進展，我們將向覆蓋7億人口的東南亞地區進行市場佈局。我們持續拓展血糖穩態調控技術的臨床應用場景，積極佈局早期阿爾茨海默病、衰弱症等新適應症領域。針對GCK-MODY及衰弱症開展的疾病首創新藥研發工作，將為華領醫藥未來五年的創新發展劃定全新方向。」業務亮點與運營進展- 商業化全面發力，盈利實現歷史性突破2025年1月1日起，公司正式全面接管华堂宁(R)在中國的商業化工作，獲得全部運營與戰略主導權，公司成功搭建了專業的銷售團隊，覆蓋全國10個銷售區域，專注於產品營銷、醫學事務及商業運營。通過人工智能賦能的數字商業化平台，運營效率與銷售生產力大幅提升，為公司商業化發展注入新活力。受益於國家醫保藥品目錄的持續廣泛覆蓋，华堂宁(R)在二級和三級醫院的處方量顯著增長，患者可及性不斷提高，通過3000多家醫院、社區衛生中心、藥房和線上渠道，惠及超過50萬名患者。報告期內，產品銷量達401.1萬盒，同比增長91%；銷售額達4.929 億元，同比增長93%，在單價保持穩定的情況下，充分印證了市場需求的強勁增長和自主商業化團隊的高效執行能力。盈利能力方面，2025年，公司毛利達到2.804億元，同比增長125%，得益於生產規模擴大及製造工藝優化，公司毛利率從2024年的48.7% 提升至56.9%，增加8.2個百分點；銷售開支僅增長1230萬元至1.655億元，占收入比例優化至33.6%，較2024年的59.9%大幅下降；商業化業務實現約1.149億元盈利（按毛利扣除銷售開支計算）。公司預期仍將持續擴充商業化團隊規模，但商業化運營的盈利趨勢也將持續增長。在2024年底終止與拜耳合作後，多格列艾汀銷售額創歷史新高，報告期內，公司稅前盈利增加至人民幣11.064億。截至2025年末，現金結餘約為人民幣10.923億元，穩健的現金情況為公司持續發展奠定了堅實基礎。- 全球佈局加速推進，核心權益得到強化公司全球化佈局邁出關鍵步伐。2026年2月27日，多格列艾汀（香港地區商品名：MYHOMSIS(R)，華領片(R)）成功獲得香港監管機構的上市批准，公司計劃2026年中正式在香港市場推出該產品，並將進一步向亞洲地區拓展。此外，公司已于2025年向澳門藥監局遞交華領片(R)（MYHOMSIS(R)）的新藥上市申請。公司在知識產權保護方面也再獲進展。2026年2月，中國國家知識產權局批准多格列艾汀專利期限補償（PTE）申請，核心專利保護期延長至2034年4月，新增5年市場獨佔權，為產品長期市場競爭提供有力保障。2025年，多格列艾汀獲中國監管機構認定為國家級創新藥及慢病有效治療藥物，國家醫保局已確認，2026-2027年，华堂宁(R)的國家醫保目錄價格維持不變，公司將持續保障產品的市場競爭力和患者可及性，尤其在二級和三級醫院，加速患者的用藥普及。- 真實世界研究推進，臨床價值獲持續驗證真實世界證據（RWE）研究持續佐證多格列艾汀在葡萄糖依賴性胰島分泌功能改善中的關鍵作用，並顯示其在糖尿病預防、緩解及延緩或預防糖尿病併發症方面的功效。HMM0701已完成入組，共招募380名2型糖尿病患者。2025年6月，在美國ADA年會上發表的中期分析結果顯示，86%的患者同時服用兩種或以上降血糖藥物，41%的患者使用胰島素。經6個月治療後，血糖控制明顯改善，糖化血紅蛋白由8.1%降至7.3%，平均TIR（目標範圍內時間）提升至70%以上。迄今為止的研究顯示，多格列艾汀與其他降糖藥物聯合使用時，患者的餐後血糖水平和β細胞功能均顯著改善。另外，在美國進行的多格列艾汀機制研究（採用雙示蹤劑測量法），為平均確診糖尿病17年的2型糖尿病患者的肝糖原生成提供了科學證據。在該研究中，患者每日服用兩次多格列艾汀，持續6周。結果顯示，多格列艾汀能增加葡萄糖直接流入肝糖原的通量，意味著其有助於恢復肝臟GK功能。結合臨床研究數據顯示，多格列艾汀可改善早期胰島素釋放和GLP-1分泌，恢復2型糖尿病患者的肝臟GK功能，不僅為控制餐後血糖波動提供重要途徑，並在控制糖尿病併發症（如糖尿病腎病變及輕度認知障礙）方面提供獨特契機。HMM0601研究已經完成臨床試驗，共納入2000名受試者，平均患病時間為7.9年，其中超過30%患病時間超過10年。初步結果顯示，多格列艾汀在中國2型糖尿病患者中安全性、耐受性良好。研究中未觀察到新的不良反應，不良反應發生率維持在III期臨床試驗中觀察到的低水平，患者的用藥依從性普遍較高，平均依從率約為95%。在本研究中，80%的受試者已使用一種或多種口服降血糖藥，20%的受試者使用胰島素。多格列艾汀不僅在整體患者群體中展現出良好的療效及安全性，在老年、肥胖及高血糖患者群體中同樣有效，無論作為單藥治療或與二甲雙胍、SGLT-2抑制劑、胰島素及其他藥物聯合使用。頂線結果將於2026年ADA年會上發表。- 臨床研發持續深化，新適應症不斷拓展多格列艾汀用於治療MODY-2患者。中國內地及香港地區醫學專家已獨立開展多格列艾汀用於MODY-2治療的臨床研究及臨床前研究。MODY-2（又稱GCK-MODY）是一種單基因疾病，患者因葡萄糖激酶基因(GCK)存在遺傳缺陷，導致血糖升高及第二時相胰島素釋放顯著減少。在中國，MODY-2患者群體規模約為170萬人。此類患者確診糖尿病時年齡偏小，且由於現有治療藥物療效不佳，這一患者群體存在未被滿足的醫療需求。中國研究人員在針對MODY-2患者的臨床研究中報告指出，對於先前使用二甲雙胍、TZD、DPP-4抑制劑及SGLT-2抑制劑仍無法控制高血糖的MODY-2患者，多格列艾汀能有效將血糖降至正常水平。其他結果顯示，單劑量多格列艾汀可顯著改善這類患者的整體葡萄糖敏感性及第二時相胰島素分泌，表明多格列艾汀具有調節GLP-1分泌的獨特作用機制。基於以上結果，華領醫藥已與國家藥品監督管理局（NMPA）藥品審評中心溝通，將於2026年提交多格列艾汀用於MODY-2患者的IND申請。多格列艾汀用於糖尿病預防。糖尿病預防是華領醫藥的重要研發重點。公司已於香港啟動針對糖尿病前期糖耐量異常（IGT）受試者及早期糖尿病患者的SENSITIZE 3臨床研究。這項雙盲安慰劑對照研究將評估受試者在靜脈葡萄糖耐量試驗及口服葡萄糖耐量試驗下的血糖控制及胰島功能，以更明確界定臨床治療基線及終點指標。我們預計於2026年完成研究後，將在中國及亞太地區探索提交多格列艾汀用於糖尿病預防的IND申請的新機遇。多格列艾汀用於神經退行性疾病。研究顯示，中國老年人的輕度認知障礙患病率約為15.5%，美國則約為22%；該症狀在2型糖尿病患者中也相當常見，發病率達45%。多格列艾汀用於神經退行性疾病的研究已成為公司藥物研發工作的新焦點。通過全基因組關聯分析(GWAS)及孟德爾隨機化（MR）研究，我們發現GK基因激活在預防人類記憶力衰退及認知障礙方面具有重要作用。同時我們也發現，餐後血糖波動與阿茲海默症及失智症密切相關。血糖穩態異常及糖尿病狀況會導致大腦葡萄糖轉運蛋白及胰島素受體表達減少，而低劑量多格列艾汀可預防該功能損傷。我們已確認多格列艾汀在治療輕度認知障礙方面的潛在價值，並將於未來啟動針對該疾病領域的首創療法的相關臨床研究。多格列艾汀用於治療衰弱症。衰弱症是一種與年齡相關的老年綜合症，其特徵為對內外應激因子的耐受性降低。約17%的美國人及11%的亞洲人（50歲以上）患有衰弱症，而處於衰弱症前期者則分別約占此兩個群組的50%及47%。衰弱症並非單一器官疾病，而是多系統內穩態失調所導致的後果。遺傳學證據支持GK激活對降低衰弱症風險具有因果作用。我們計劃於未來啟動臨床研究，以推進多格列艾汀在衰弱症治療領域的應用。聯合用藥用於糖尿病及併發症的治療。臨床與基礎研究結果顯示，多格列艾汀能恢復胰腺在葡萄糖刺激下的胰島素及GLP-1分泌，也可以通過恢復2型糖尿病患者肝臟葡萄糖激酶功能，改善肝臟胰島素敏感性並降低肝臟胰島素抵抗。多格列艾汀與DPP-4抑制劑、SGLT-2抑制劑及GLP-1受體激動劑的聯合使用已證明可有效調節脂質代謝，與抗癌PI3K抑制劑聯合使用的研究也為血糖穩態管理帶來獨特優勢。- 產品管線豐富多元，創新佈局未來增長華領醫藥在核心產品基礎上持續豐富管線佈局。依託多格列艾汀與二甲雙胍聯合用藥在III期臨床試驗和真實世界應用中取得的優異數據，公司加速推進多格列艾汀與二甲雙胍固定複方製劑（FDC）的研發。該製劑為每日兩次給藥方案，適用于單用二甲雙胍血糖控制不佳的2型糖尿病患者，旨在以進一步提升患者的用藥依從性。公司已向NMPA提交IND申請文件。此外，GMP商業化生產工藝也已成功開展，為2027年新藥上市申請的關鍵生物等效性研究做好準備。臨床研究顯示，多格列艾汀與二甲雙胍聯用能夠更好地控制血糖，降低餐後血糖，改善空腹血糖，為優化血糖穩態終點提供了新的臨床價值。第二代GKA的研發取得重要突破。作為肥胖2型糖尿病患者每日一次治療的緩釋新片劑，公司已在美國啟動多格列艾汀多劑量遞增（MAD）研究，以探討第二代GKA在血糖穩態控制方面的療效及新藥的作用機制，首例患者已於2025年12月入組，預計2026年中公佈頂線數據。同時，公司還在探索多格列艾汀與GLP-1受體激動劑、SGLT-2抑制劑等藥物的聯合治療方案。近期，在一項中國的臨床試驗中，研究者報告：多格列艾汀聯合司美格魯肽治療12周，療效顯著優於司美格魯肽單藥治療。聯合治療組在血糖控制、體重相關指標及β細胞功能等多項關鍵指標上均表現更優。財務摘要截至2025年12月31日，- 华堂宁(R)全年銷量約401.1萬盒，相較2024年全年，同比增長91%，實現營收約4.929億元，同比增長93%。- 毛利約人民幣2.804億元，同比增長125%，毛利率提升至56.9%；- 稅前盈利約人民幣11.064億元，較2024年增長542%；- 銀行結餘及現金約人民幣10.923億元，資金狀況穩健；- 總開支約人民幣4.334億。前瞻性聲明本文包含有關華領醫藥以及產品未來預期、計劃和前景的陳述。該等前瞻性陳述僅與本文作出該陳述當日的事件或資料有關，可能因未來發展而出現變動。除法律規定外，於作出前瞻性陳述當日之後，無論是否出現新資料、未來事件或其他情況，我們並無責任更新或公開修改任何前瞻性陳述及預料之外的事件。請仔細閱讀本文並理解，由於各種風險、不確定性或其他法定要求我們的實際未來業績或表現可能與預期有重大差異。關於華領華領醫藥（「本公司」）是一家總部位於中國上海的創新藥物研發和商業化公司，在美國、中國香港設立了公司。華領醫藥專注於未被滿足的醫療需求，為全球患者開發全新療法。華領醫藥彙聚全球醫藥行業高素質人才，融合全球創新技術，依託全球優勢資源，研究開發突破性的技術和產品，引領全球糖尿病醫療創新。公司核心產品华堂宁(R)（多格列艾汀片）以葡萄糖傳感器葡萄糖激酶為靶點，提升2型糖尿病患者的葡萄糖敏感性，改善患者血糖穩態失調。2022年9月30日，华堂宁(R)已獲得中國國家藥品監督管理局（NMPA）的上市批准，用於單獨用藥或者與二甲雙胍聯合用藥，治療成人2型糖尿病。對於腎功能不全患者，無需調整劑量，是一款可用於腎功能損傷的2型糖尿病患者的口服降糖藥物。2026年2月，多格列艾汀（商品名：MYHOMSIS(R)，華領片(R)）獲得中國香港特別行政區政府衛生署藥物辦公室的上市批准。詳情垂詢華領醫藥網址：www.huamedicine.com投資者電郵：ir@huamedicine.com媒體電郵：pr@huamedicine.com新聞免責聲明本材料，如為上下文論述的準確性和完整性，提及在中國上市的產品相關信息的，特別是標識或要求，應遵循中國監管機構批准的相關文件。另外，相關信息不應被解讀為對任何藥物或者診療方案的推薦或者宣傳，亦不應替代任何醫療衛生專業人士的醫療建議，涉及醫療的相關事宜務必諮詢醫療衛生專業人士。 Copyright 2026 亞太商訊 via SeaPRwire.com. All rights reserved. www.acnnewswire.com

HONG KONG, Mar 27, 2026 - (ACN Newswire via SeaPRwire.com) – 26 March, Unisound (09678.HK) announced its audited annual results for the year ended December 31, 2025. As the Company's first annual results announcement since listing, it underscores strong growth momentum and continued improvement in its financial profile.Revenue Mix Continues to Improve, with Faster Growth in H2For the full year of 2025, Unisound achieved total revenue of $175 million, representing a year-on-year (YoY) increase of 29%. Revenue in the second half of the year increased by 33% YoY to $117 million.It is worth noting that the Company's large language model (LLM) business generated a full-year revenue of $88.43 million, surging by over 10 times YoY. In particular, this business contributed approximately $72.49 million in H2 revenue, five times the level recorded in H1, demonstrating a compelling capacity for large-scale commercial application.Losses Narrowed Significantly, Making the Path to Profitability Increasingly ClearAlongside the rapid revenue growth, the Company's losses improved markedly. In the second half of 2025, the Company's net loss narrowed by 84% YoY, and its adjusted loss narrowed by 92% YoY, approaching break-even. This reflects the Company's ongoing improvements in cost control and operational efficiency.Simultaneously, some of the Company's operating metrics saw marked improvement. The adjusted expense ratio declined significantly by 10 percentage points YoY, while selling expenses decreased rather than increased and accounted for only 5.4%, highlighting a clear improvement in cost-to-efficiency ratio. In 2025, revenue per employee reached $365,300, up 25% YoY from $292,900 in 2024. Employee productivity continued to lead the industry, clearly underscoring the Company's core strengths in technology-driven, lean operations.Dual-Engine Strategy Gains Traction, with AI in Healthcare and AI in Daily Life Advancing in TandemIn 2025, driven by both technological breakthroughs and policy tailwinds, global demand for AI continued to rise. Unisound adhered to its "Strong Foundation Model + Deep Application" strategy, continued to strengthen its multimodal technology foundation, and drove the continuous elevation of the global influence of its proprietary large model matrix in fields such as healthcare, speech, and OCR.On the commercialization front, the Company leveraged its AI-native organization to accelerate business execution, and its dual-engine strategy in AI in Healthcare and AI in Daily Life delivered notable results. During the reporting period:The AI in Daily Life business achieved revenue of $140 million, a YoY increase of 30.8%. Among this, the Transportation segment recorded nearly 40% YoY growth. At present, AI agent applications based on the Shanhai large model have been deployed in more than 10 cities, including Qingdao, Ningbo, Shenzhen and Nanning. In addition, cumulative AI chip shipments exceeded 110 million units, further validating the Company's scale capabilities in endpoint AI products.The AI in Healthcare business achieved revenue of $35.38 million, a YoY increase of 22.3%, with average revenue per customer growing by 53.2% YoY. In 2025, over 70% of the hospitals the Company collaborated with were tertiary hospitals, and more than one-third of customers had maintained continuous cooperation for over three years. The medical-record entry and generation products powered by the medical large model delivered a 10-fold YoY increase in full-annual medical record generation at a single campus of a leading Class III hospital. The commercial insurance AI agent platform recorded a 37-fold YoY increase in case processing volume. In deep cooperation with a leading insurance group, the expense control rate was effectively raised to approximately 20%, delivering more than $145 million in incremental cost management compared with traditional review methods, comprehensively empowering insurance institutions to refine their medical risk management operations.Continued R&D Investment Strengthens the Technology MoatTo consolidate its industry-leading position, the Company continued to invest heavily in R&D in 2025. Full-year R&D expenses exceeded $55.09 million, accounting for 75% of the Company's adjusted operating expenses, while R&D personnel accounted for 69% of the total workforce. This sustained investment drove breakthroughs across multiple technology areas. For example, in the MedBench 4.0 evaluation, the Company ranked first place in three technical paradigms: "Medical AI Agent," "Medical Large Language Model," and "Medical Multimodal Large Model," earning a "Triple Crown."Outlook: Deepening the Technological Foundation and Expanding Application BoundariesLooking ahead, Unisound will continue to deepen its "Strong Foundation Model + Deep Application" strategy. On the technological front, the Company will continue to increase strategic investment in foundational large models and strive to maintain a world-class level. On the application front, it will use the large-scale expansion of MaaS (Model-as-a-Service) and AI agents as its core growth engine, driving exponential growth in its AI in Daily Life and AI in Healthcare businesses. Meanwhile, the Company is actively exploring the establishment of a recurring revenue system through models such as API calls and Token-based billing, and regards opportunities in consumer-facing (C-end) products as a second growth curve to further expand its commercialization boundaries.Between Q2 and Q3 2026, Unisound will launch a native AI agent large model for programming and office applications, which is expected to double both intelligence density and token production efficiency. Copyright 2026 ACN Newswire via SeaPRwire.com. All rights reserved. www.acnnewswire.com

香港, 2026年3月27日 - (亞太商訊 via SeaPRwire.com) - 3月26日，雲知聲（09678.HK）發佈截至2025年12月31日止年度的經審核全年業績，展現上市後首份成績單強勁的增長動能與持續優化的財務結構。營收結構持續優化，下半年增長提速2025年全年，雲知聲實現總營收12.1億元人民幣，同比增長29%。其中，下半年收入同比增長33%，達8.1億元。值得關注的是，公司大模型業務全年收入6.1億元，同比增長超10倍。尤其是下半年，該業務貢獻收入約5億元，為上半年規模的5倍，顯示出強勁的規模化落地能力。虧損大幅收窄，盈利路徑日漸清晰在營收高速增長的同時，公司虧損狀況顯著改善。2025年下半年，公司淨虧損同比收窄84%，經調整後虧損同比收窄92%，接近盈虧平衡點，反映出公司在成本控制與運營效率方面的持續優化。同時，公司的部分經營指標也得到明顯改善。經調整營業費用率較去年同比大幅下降10%，銷售費用不升反降，佔收入比重僅為5.4%，費效比提升明顯。從數據端來看，2025年公司人均產值為252萬元/人，相較24年的202萬元同比增長25%，人均創效能力持續領跑行業，直觀彰顯了公司技術驅動、精益運營的核心優勢。雙輪驅動戰略落地，智慧醫療與智慧生活齊頭並進2025年，在技術突破與政策紅利的雙重驅動下，全球人工智能市場需求持續升溫。雲知聲堅持「強基模+深應用」戰略，持續夯實全模态技術底座，推動自研大模型矩陣在醫療、語音、OCR等領域的全球影響力不斷提升。在商業化層面，公司以AI原生組織推動業務落地，智慧醫療與智慧生活雙輪驅動戰略成效顯著。報告期內：智慧生活業務實現收入9.68億元，同比增長30.8%。其中，智慧交通業務同比增長近40%，目前，已在青島、寧波、深圳、南寧等10餘個城市落地基於山海大模型的智能體應用。此外，AI芯片累計出貨量突破1.1億顆，進一步驗證公司在終端AI產品的規模化能力。智慧醫療業務實現收入2.44億元，同比增長22.3%，客單價同比增長53.2%。2025年，合作的醫院中超70%為三級醫院，且超過三分之一客戶已經連續合作三年以上；而基於醫療大模型的病歷錄入與生成產品已在某頭部三甲醫院單院區實現全年病歷生成同比增長10倍；商業保險智能體平台案件處理量同比增長37倍；與頭部保險集團的深度合作中，控費率水平有效提升至約20%，相較傳統審核方式實現超10億元級別的增量成本管控，全面賦能保險機構在醫療風控領域的精細化運營。持續加碼研發，夯實技術護城河為鞏固行業領先地位，2025年公司持續在技術端大力投入，全年研發費用超3.8億元，佔經調整三費的75%；研發人員佔比達69%。持續的研發投入在多個技術領域取得突破，如在MedBench 4.0評測中，公司一舉斬獲「醫療智能體」「醫療大語言模型」「醫療多模态大模型」三項技術範式第一，榮膺「三冠王」。未來展望：深耕技術底座，拓展應用邊界展望未來，雲知聲將繼續深化「強基模+深應用」戰略。技術層面，公司將持續加大對基座大模型的戰略性投入，力爭保持全球一流水平；應用層面，將以MaaS（模型即服務）與智能體的規模化拓展為核心增長引擎，推動智慧生活與智慧醫療業務的指數級增長。同時，公司正積極探索以API調用、Token計費等模式構建經常性收入體系，並將C端產品機會作為第二增長曲線，進一步拓展商業化邊界。2026年第二季度，雲知聲將推出面向編程和辦公的原生智能體大模型，並預計能實現智能密度和Token生產效率的倍增。 Copyright 2026 亞太商訊 via SeaPRwire.com. All rights reserved. www.acnnewswire.com

香港, 2026年3月27日 - (亞太商訊 via SeaPRwire.com) - 2026年3月26日，北京城建設計發展集團股份有限公司（"本公司"或"公司"，簡稱"城建設計"，股票代碼：1599.HK）董事會（"董事會"）欣然公佈本公司及其子公司（合稱"本集團"）截至2025年12月31日止年度（"2025年度"或"報告期"）的經審計業績。2025年，公司面對市場持續下行壓力，緊緊圍繞高質量發展，迎難而上、實幹擔當，聚焦主責主業，推動全產業鏈協同發力，階段性完成了"十四五"規劃主要目標任務，為新征程加快發展積蓄了強勁動能。截至2025年12月31日止年度，本集團實現收入為人民幣75.27億元。本集團實現淨利潤為人民幣5.36億元，同比上漲1.52%。綜合毛利率19.85%，同比上漲1.77%。核心主業與新興領域協同發力，高端諮詢品牌效應顯現設計、勘察及諮詢板塊為本集團的傳統和主營核心業務，報告期內，本集團軌道交通領域中標成都27號線二期、廈漳泉城際鐵路（廈門段）等重點項目；既有線改造市場成效顯著，中標北京、南京、哈爾濱、長春、瀋陽等一批代表性項目，市場份額保持領先；高端諮詢品牌效應持續顯現，成功承擔了香港鐵路標準、北京三期線網技術標準等標杆項目，專業服務能力穩步提升；境外業務紮實推進，在香港、新加坡、安哥拉、哈薩克斯坦、哥倫比亞持續獲取訂 單，新簽合同額突破人民幣1億元；民建、市政設計走特色化發展之路，在居住建築、大型TOD、校園、道路等傳統領域精耕細作，積極向展陳、城市更新、水環境治理領域延伸佈局。截至2025年12月31日止年度，本集團設計、勘察及諮詢板塊業務收入人民幣40.89億元。其中城市軌道交通工程板塊收入人民幣29.38億元，工業與民用建築和市政工程板塊收入人民幣11.51億元。本集團工程承包業務板塊專注於服務城市軌道交通建設項目和相關基礎設施建設項目，2025年，本集團中標北京軌道交通R4線一期北段01標、03標、M101線05標、市郊鐵路東北環線03標等項目，進一步鞏固了北京核心市場，在手工程承包項目主要集中在北京、廣州、重慶、烏魯木齊及青島等城市。截至2025年12月31日止年度，本集團工程承包業務板塊實現收入人民幣34.38億元。新建項目與存量改造雙線發力，中標額突破81億元，在手訂單儲備充足2025年，軌道交通行業面臨市場持續下行、招標規模顯著縮減、行業競爭加劇及宏觀經濟形勢不確定性增強的局面，公司始終全力以赴力爭中標軌道交通新建項目，尤其注重穩固北京區域市場份額。在守住基本盤的同時，積極佈局既有線改造、城市更新、能源、數字化及智慧等其他高潛力板塊，以應對市場變化並提升抗風險能力。截至2025年12月31日，公司中標金額人民幣81.71億元，其中設計、勘察及諮詢業務板塊中標人民幣26.39億元，工程總承包板塊中標人民幣55.32億元。報告期末公司在手合同額為人民幣251.43億元。2026年展望：錨定"十五五"開局，推動高質量發展2026年是"十五五"開局之年，面對深刻變化的市場形勢和艱巨繁重的發展任務，我們要積極把握戰略機遇，主動適應行業發展新格局，以穩中求進為總基調，以推動高質量發展為主題，以改革創新為根本動力，錨定打造"以設計為引領的城市建設綜合服務商"戰略目標，確保"十五五"開好局、起好步。有關城建設計北京城建設計發展集團股份有限公司（股份代碼：1599.HK）是國內第一家以城市軌道交通設計諮詢為引領的H股上市企業。公司前身是北京城建設計研究總院成立於1958年，是為中國首條地鐵北京地鐵1號線的勘察設計而成立。擁有國內設計勘察行業最高資質—綜合甲級資質。作為行業龍頭和市場規範的制定者，公司由成立至今仍保持市場佔有率第一的位置。基本業務涵蓋投融資、勘察設計諮詢、工程總承包、科技產業化、運營管理的城市軌道交通全產業鏈。公司市場覆蓋了全國已批復軌道交通建設規劃城市的80%，業務拓展到了國內近70個城市，在50多個城市擁有分支機構。新聞垂詢：千里國際顧問有限公司fancywang@maxima.hk Copyright 2026 亞太商訊 via SeaPRwire.com. All rights reserved. www.acnnewswire.com

香港, 2026年3月27日 - (亞太商訊 via SeaPRwire.com) - 2026年3月26日，心瑋醫療（06609.HK）公佈了2025年業績公告。2025度，公司收入4.08億元，同比增長46.9%，淨利潤8334萬元，較上年度虧損約1362萬元實現重大扭虧為盈。這一轉變主要由於公司在缺血性卒中、出血性卒中及介入通路三大業務板塊均實現了收入的快速增長，同時公司的經營效率進一步提升。2025年，公司的缺血性卒中業務收入同比增長31.8%，主要由於：(1)公司具有差異化競爭優勢的顱內血栓抽吸導管得到臨床的廣泛認可，大腔抽吸及級聯抽吸技術(CATCH)被納入《急性缺血性卒中血管內治療技術中國專家共識2025》，產品進入超過450家醫院使用，收入規模快速提升；(2)成熟產品在納入集采後，銷量快速增長。在出血性腦卒業務中，公司已構建完整動脈瘤治療解決方案。公司的顱內支架（獲NMPA創新醫療器械認定）在首個商業化年度累計進入約500家醫院使用，帶動栓塞彈簧圈的市場份額快速提升。同時，公司的血流導向裝置於2025年獲NMPA批准上市，實現臨床推廣和應用。基於前述原因，公司的出血性卒中業務收入在2025年同比增長223.2%。在介入通路業務中，公司的明星產品血管封堵器累計進入超過1800家醫院使用，年終端醫院臨床使用量超過20萬條，在2025年實現單產品收入過億。與此同時，公司正推動第二代血管封堵器的開發和商業化，以繼續擴大市場份額。公司的毛利率從2024年度的65.4%提升至2025年的70.9%，主要由於高毛利創新產品的收入占比提升，以及公司持續推動的生產工藝改進、供應鏈優化等降本措施的有效實施。不斷完善的產品佈局以及持續的降本增效工作，使公司在面臨激烈的市場競爭情況下，仍能保持優質的產品品質及突出盈利能力。公司在業務規模擴大的同時，費用控制效果顯著，銷售及管理費用率較2024年相比從49.6%降至45.8%。報告期內，公司發生研發費用人民幣4076萬元，主要用於神經介入醫療器械及腦機介面等創新產品的開發。截至目前，公司已取得以下各項進展：(1)在缺血性卒中領域，公司已取得顱內血栓抽吸導管、取栓支架及配套通路產品的註冊證。公司的自膨式顱內藥物洗脫支架已完成對照臨床試驗，註冊申請已獲NMPA受理。根據公開信息查詢結果，目前全球未有類似產品獲批上市，公司在此類產品的研發進度上領先業界。在頸動脈狹窄領域，公司正推動開展頸動脈支架的臨床試驗工作；(2)在出血性卒中領域，公司是獲證最全面的國產公司，實現顱內支架（獲NMPA創新醫療器械認定）、血流導向裝置、栓塞彈簧圈、神經血管封堵球囊導管的完整佈局；(3)同時，公司正積極推進創新產品介入式腦機接口的研發工作。該產品在有效提取大腦信號以用於完成人機交互的同時，保障了手術的安全性和產品長期植入的穩定性，有望在2026年開展首例人體臨床試驗。2025年，公司的海外市場收入較2024年增長101.3%，這主要歸功於公司快速推進的海外產品註冊工作及產品推廣工作。海外市場方面，公司的取栓支架、封堵球囊導管、遠端通路導管以及微導管已取得CE或FDA認證，並在其他13個國家或地區取得56項註冊證書。截至目前，公司還在其他29個國家或地區開展超過130個產品註冊工作，擴展銷售管道，為實現海外銷售的長期目標建立基礎。2025年，公司經營性現金流1.55億元，帳面現金及存款7.86億元，整體資金狀況穩健。依託扎實的財務實力，公司已於2025年完成股份回購3936萬港元，並將持續推進股份回購工作，積極維護全體股東利益。此外，公司計劃於2026年提交A股科創板上市申請，借助登陸境內資本市場進一步提升股東回報水平與股份市場流動性。 Copyright 2026 亞太商訊 via SeaPRwire.com. All rights reserved. www.acnnewswire.com

Financial HighlightsRMB 100 millionFor the 12 months ended 31 DecemberChange (%)20252024Revenue1566.111,776.64-11.85% Profit28.4265.53-56.64% Profit before Tax28.1665.95-57.30% Gross Profit194.95222.47-12.37% Gross Profit Margin12.45%12.52%-0.07pct Net Profit13.3741.95-68.12% Net Profit Attributable to Shareholders and Other Equity Holders2.2129.72-92.57% Net cash flows from operating activities 185.1492.6499.86% Dividend per share (RMB/share, tax inclusive)RMB 0.179RMB 0.176N/A Total dividend payout9.399.45-0.60%  Performance Highlights1. Solid operating core segments with resilient high-quality development: In 2025, the Group achieved revenue of RMB 156.611 billion, net profit of RMB 1.337 billion, and maintained a gross profit margin of 12.45%, with a balanced domestic and overseas revenue structure.2. Dual improvement in cash flow and financial quality, with significantly enhanced risk resilience: Net cash flows from operating activities increased substantially by 99.86% to RMB 18.514 billion, while the cash and cash equivalents as of the end of the Year reached RMB 24.3 billion; the scale of interest-bearing debt decreased by RMB 4.7 billion year-on-year (“YoY”) to RMB 34.4 billion, and net interest expenses decreased by approximately RMB 730 million YoY, with the financial structure continuing to be optimized.3. Cash dividends and share buybacks implemented in parallel to reward investors: The Group proposes a cash dividend of RMB 0.179 per share (tax inclusive) for 2025. Together with multiple rounds of H-share and A-share buyback plans launched during the Year, the total proposed dividend and completed buybacks for 2025 amounted to RMB 1.852 billion.4. Significant improvement in profitability of energy-related businesses, becoming a key growth driver of the Group: Net profit of the offshore engineering segment and the financial and asset management segment (primarily drilling platform leasing) increased by approximately RMB 1.212 billion in total, while the energy, chemical and liquid food equipment segment increased by RMB 308 million. Among them, the gross profit margin of the offshore engineering segment increased significantly by 5.72 percentage points to 14.83%. Orders on hand for offshore engineering and energy, chemical and liquid food equipment reached US$5.09 billion and RMB 29.75 billion, respectively, with certain shipyards’ production schedules extending to 2030.5. Logistics-related businesses continued to serve as the Group’s “ballast stone”: During the Year, businesses such as container manufacturing and road transportation vehicles were affected by exchange rate fluctuations and cyclical changes, resulting in pressure on gross profit margins and profitability. However, the core segments remained solid, and the Group’s competitive advantages in the industry continued to be consolidated. Core products such as standard dry containers, reefer containers, tank containers and semi-trailers have maintained the world’s No.1 position for many consecutive years.6. Breakthroughs in both technology and orders in key businesses, with competitiveness highly recognised: In the high-end offshore engineering equipment sector, CIMC Raffles successfully developed the most complex products in the offshore industry, including FPSO/FLNG, becoming the only enterprise in China with dual-project EPCI general contracting capabilities; in the modular data center sector, the Group providing technical and manufacturing delivery services of prefabrication data center to industry customers exceeding 300MW, leading new transformation in computing power infrastructure.HONG KONG, Mar 26, 2026 - (ACN Newswire via SeaPRwire.com) – China International Marine Containers (Group) Co., Ltd. (“CIMC Group” or the “Group”, stock code: 000039.SZ/02039.HK) is pleased to announce the audited annual results for the 12 months ended 31 December 2025 (the “Year”).The Group’s management stated, “In 2025, profound global changes unseen in a century accelerated, and the global economy demonstrated resilience amid volatility. Positioned in an era of both opportunities and challenges, the Group closely adhered to the strategic theme of “accelerating the construction of new growth drivers and focusing on promoting high-quality development”. While stabilising its operating fundamentals, the Group further deepened its forward-looking strategic layout in the energy business and achieved fruitful results. For the year of 2025, the Group recorded revenue of RMB 156.61 billion and net profit of RMB 1.34 billion. Cash flows from operating activities increased significantly by 99.9% to RMB 18.51 billion, with the asset structure continuously optimized and risk resilience further enhanced.”In particular, to sincerely reward investors, CIMC Group proposes to distribute a cash dividend of RMB 0.179 per share (tax inclusive) to all shareholders for 2025, amounting to a total proposed cash dividend of RMB 939 million (tax inclusive). Meanwhile, the Group implemented share buybacks totalling RMB 913 million during 2025, bringing the combined total to RMB 1.852 billion.Segments Results (RMB 100 million)2025 Business indicatorsRevenueAs % of the total revenueGross profitAs % of the gross profitGross profit marginNet profitContainer manufacturing430.0927.46%57.5529.52%13.38%18.82Road transportationvehicles201.7812.88%32.0616.45%15.89%9.27Energy, chemical, and liquid food equipment271.9217.36%40.2420.64%14.80%10.40Offshore engineering179.3811.45%26.6013.65%14.83%10.57Logistics services267.9317.11%16.708.57%6.23%3.64Airport facilities and logistics equipment/fire safety and rescue equipment76.194.86%15.147.76%19.87%2.64Total of major segments1427.2991.12%188.2996.59%13.19%55.34Core Business Performance1. In logistics field:In the container manufacturing business, during the Year, despite negative supply chain factors such as U.S. tariff policies and geopolitical conflicts, global merchandise trade demonstrated strong resilience. Intra-regional trade, Asia-Europe routes and emerging market routes became the main drivers of incremental growth. Meanwhile, factors such as detours around the Red Sea, port congestion, environmental requirements in shipping and increasing complexity of trade routes reduced transportation efficiency, structurally boosting underlying demand and pushing the global container fleet into a new structural phase. As a result, overall demand for new containers in 2025 remained at a relatively high level, exceeding the average of the past decade. During the Year, the production and sales volume of the Group’s container manufacturing business declined YoY, in line with overall industry expectations, but the Group maintained its global No.1 position. Accumulated sales volume of dry cargo containers reached 2,224,900 TEUs (2024: 3,433,600 TEUs), representing a YoY decrease of 35.2%. Accumulated sales volume of reefer containers reached 208,200 TEUs (same period last year: 138,600 TEUs), representing a YoY increase of 50.2%. During the Year, the container manufacturing segment recorded revenue of RMB 43.009 billion, net profit of RMB 1.882 billion, and a slight decline in gross profit margin to 13.38%.In the logistics services business, during the Year, the segment recorded revenue of RMB 26.793 billion, representing a YoY decrease of 14.64%, and net profit of RMB 364 million, representing a YoY decrease of 16.65%, in line with industry trends. CIMC Wetrans actively adjusted its business structure and integrated resources. During the Year, self-sourced cargo volume increased by 6% YoY, while second-hand container trading and warehousing distribution in port logistics reached record highs. The industry logistics business focused on key sectors such as new energy, automotive and engineering projects to consolidate its niche advantages. In 2025, CIMC Wetrans ranked among the top five for three consecutive years in the “Comprehensive List of Freight Forwarding and Logistics Enterprises” published by the China International Logistics and Freight Forwarding Association.In the road transport vehicles business, during the Year, CIMC Vehicles recorded revenue of RMB 20.178 billion, representing a YoY decrease of 3.91%, and net profit of RMB 927 million, representing a YoY decrease of 14.29%. In the domestic market, the “Star-Chained Plan” reshaped the organisational and operational model, with revenue from the China semi-trailer business increasing by 14.65% YoY and gross profit margin increasing by 3.3%YoY. In overseas markets, the Global South markets maintained high-quality growth, with revenue reaching RMB 3.09 billion during the Reporting Period, representing a YoY increase of 17.7%, sales volume increasing by 29.1% YoY, and gross profit margin increasing by 1.3 percentage points YoY.The DTB business achieved steady growth in both sales volume and revenue, with a total of 28,570 units of mounted equipment products delivered, generating total revenue of RMB 3.184 billion, representing a YoY increase of 4.97%, with further improvement in market share of core products. Meanwhile, the Group continued to actively expand R&D and sales of new energy products, comprehensively building the EV-RT ecosystem and advancing the strategic development of pure electric tractors and trailers.In the airport facilities and logistics equipment/fire safety and rescue equipment, benefiting from the release and delivery of high-quality orders, the segment recorded revenue of RMB 7.619 billion during the Year, representing a YoY increase of 5.92%, and net profit of RMB 264 million. Airport equipment successfully delivered smart boarding bridges projects for Xi’an Xianyang International Airport, Antalya Airport in Türkiye and Lanzhou Airport, and secured major projects including Phase II of Nanning Airport and corridor projects at Hangzhou Airport T2 and T4 with its independently-developed innovative prefabricated fixed bridge solutions. Logistics equipment delivered automated three-dimensional warehouse systems for supporting the petrochemical and refining integration project in China. The fire safety and rescue equipment business advanced the overseas expansion of domestically manufactured products while focusing on frontier areas such as smart fire safety and unmanned fire trucks.2. In the Energy FieldIn the energy, chemical, and liquid food equipment business, the segment recorded revenue of RMB 27.192 billion, representing a YoY increase of 6.31%, and net profit increased significantly by 42.15% to RMB 1.040 billion. Among which, CIMC Enric recorded revenue of RMB 26.326 billion, representing a y YoY increase of 6.3%.Specifically, the clean energy segment advanced both offshore and onshore businesses, maintaining leading market share in key equipment such as high-pressure and cryogenic equipment, while capturing growth opportunities in natural gas applications in water and land transportation and power generation, and actively expanding into emerging markets for special industrial gas equipment in high-tech industries. In 2025, the segment secured new orders of RMB 22.229 billion, a record high. Among these, orders on hand for offshore clean energy-related business exceeded RMB 19 billion as of the end of 2025, with shipbuilding schedules extending to 2028. During the Year, the second coke oven gas comprehensive utilisation project — Linggang Phase I project — was successfully put into operation, and China’s first domestic mass-production bio-methanol (green methanol) project of CIMC Enric was completed and commenced operation. The chemical and environmental segment maintained its leading market share, while the medical equipment components and after-sales service businesses achieved steady growth. As of the end of 2025, orders on hand increased by 36.27% YoY to RMB 1.276 billion, providing strong support for future development. The liquid food segment maintained stable profitability, with gross profit margin increasing to 21.7% YoY.In the offshore engineering business, the Group’s core operating entity, CIMC Raffles, successfully achieved a strategic transformation from “manufacturing-led” to integrated “design + construction + integration” services, maintaining a leading position in the domestic market and emerging as an important new force in the international offshore engineering market. During the Reporting Period, the segment recorded revenue of RMB 17.938 billion, representing a YoY increase of 8.35%, and net profit of RMB 1.057 billion, becoming the Group’s second-largest profit contributor. Benefiting from the recovery of the global offshore engineering market, demand for high-end oil and gas equipment represented by FPSO/FLNG remained strong, while the industry accelerated its transition toward green and intelligent development, driving steady growth in new energy equipment orders. During the year, the Group secured new contract orders of US$1.20 billion, including 12+8 container feeder vessels, 2 offshore engineering special vessels and other module orders. As of the end of 2025, the accumulated value of orders on hand reached US$5.09 billion, with orders for oil & gas and special vessel accounting for approximately 70% and 30%, respectively. The Longkou base has scheduled production through to 2030.In the offshore engineering asset operation and management business, the Group continued to leverage its existing project experience and business capabilities, enhancing asset utilisation through its strong offshore platform operation and management capabilities. During the Reporting Period, the sixth-generation semi-submersible drilling platform “Deepsea Yantai” completed lease renewal, the ultra-deepwater semi-submersible drilling platform “Blue Whale No.1” signed a new lease with an international client, and the semi-submersible lifting/life platform “Blue Gretha (formerly Huadian CIMC 01)” also secured a new lease with an international client. Other platforms actively participated in market tenders to explore opportunities for asset disposal and leasing. During the Reporting Period, the average daily lease rate of semi-submersible and jack-up drilling platforms both recorded year-on-year increases.Future Development and ProspectsThe Group’s management stated, “The year 2026 marks the beginning of the ‘15th Five-Year Plan’. Starting from a newly upgraded brand identity, the Group will closely focus on ‘consolidating foundations, driving innovation, improving quality and efficiency’, and adopt a more proactive strategic approach to foster new opportunities and open new horizons amid complex changes, striving to build a ‘“becoming a high quality and trustworthy world-class multimodal transport enterprise.”About China International Marine Containers (Group) Co., Ltd.The CIMC Group is a world-leading equipment and solution provider in the logistics and energy industries, with its industry clusters mainly covering the logistics and energy fields, continuously strengthening its leading market position. In the logistics field, the Group continues to adhere to container manufacturing as its core business, based on which it has incubated the road transportation vehicles business and the airport facilities and logistics equipment / fire safety and rescue equipment business, supplemented by the logistics services business and recycled load business, providing products and services in the professional logistics field. In the energy field, the Group is principally engaged in the energy, chemical and liquid food equipment business and the offshore engineering business. Meanwhile, the Group continues to develop emerging industries and possesses financial and asset management businesses that serve the Group itself. As a diversified multinational industrial group serving the global market, CIMC has over 300 member enterprises across Asia, North America, Europe, and Australia, with a total of four listed companies, and customers and sales networks covering more than 100 countries and regions worldwide. In 2025, the Group recorded revenue of RMB 156.6 billion, ranking 154th on the 2025 Fortune 500 China list. The Group has maintained the world’s No.1 position for many consecutive years in core products such as standard dry containers, reefer containers, tank containers and semi-trailers. For more information, please visit http://www.cimc.com/. Copyright 2026 ACN Newswire via SeaPRwire.com. All rights reserved. www.acnnewswire.com